Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

UvrABC system protein C

Gene

uvrC

Organism
Salmonella gallinarum (strain 287/91 / NCTC 13346)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:SG1107
OrganismiSalmonella gallinarum (strain 287/91 / NCTC 13346)
Taxonomic identifieri550538 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000008321 Componenti: Chromosome

Subcellular locationi

B5R896:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000995141 – 610UvrABC system protein CAdd BLAST610

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Structurei

3D structure databases

SMRiB5R896.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 94GIY-YIGUniRule annotationAdd BLAST79
Domaini204 – 239UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

KOiK03703.
OMAiLFPIRQC.
OrthoDBiPOG091H01BS.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC. 1 hit.
InterProiView protein in InterPro
IPR000305. GIY-YIG_endonuc.
IPR035901. GIY-YIG_endonuc_sf.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR036876. UVR_dom_sf.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
PfamiView protein in Pfam
PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
SMARTiView protein in SMART
SM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiView protein in PROSITE
PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.

Sequencei

Sequence statusi: Complete.

B5R896-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEIFDAKAF LKTVTSQPGV YRMYDAGGTV IYVGKAKDLK KRLSSYFRSN
60 70 80 90 100
LASRKTEALV AQIQHIDVTV THTETEALLL EHNYIKLYQP RYNVLLRDDK
110 120 130 140 150
SYPFIFLSGD THPRLAMHRG AKHAKGEYFG PFPNGYAVRE TLALLQKIFP
160 170 180 190 200
IRQCENSVYR NRSRPCLQYQ IGRCLGPCVA GLVSEEEYAQ QVEYVRLFLS
210 220 230 240 250
GKDDQVLTQL IARMEKASQD LAFEEAARIR DQIQAVRRVT EKQFVSNAGD
260 270 280 290 300
DLDVIGVAFD AGMACVHVLF IRQGKVLGSR SYFPKVPGGT ELGEVVETFV
310 320 330 340 350
GQFYLQGSQM RTLPGEILLD FNLSDKTLLA DSLSELAGRS IHVQTKPRGD
360 370 380 390 400
RARYLKLART NAATALITKL SQQSTITQRL TALAAVLKLP AIKRMECFDI
410 420 430 440 450
SHTMGEQTVA SCVVFDANGP LRAEYRRYNI AGITPGDDYA AMNQVLRRRY
460 470 480 490 500
GKAIEESKIP DVILIDGGKG QLAQAKAVFA ELDVPWDKHR PLLLGVAKGA
510 520 530 540 550
DRKAGLEILF FEPEGEGFSL PPDSPALHVI QHIRDESHDH AIGGHRKKRA
560 570 580 590 600
KVKNTSTLET IEGVGPKRRQ MLLKYMGGLQ GLRNASVEEI AKVPGISQGL
610
AEKIFWSLKH
Length:610
Mass (Da):67,991
Last modified:November 4, 2008 - v1
Checksum:i3EB0A5A0D668C8CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM933173 Genomic DNA. Translation: CAR36992.1.
RefSeqiWP_001289466.1. NC_011274.1.

Genome annotation databases

KEGGiseg:SG1107.

Similar proteinsi

Entry informationi

Entry nameiUVRC_SALG2
AccessioniPrimary (citable) accession number: B5R896
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 4, 2008
Last modified: October 25, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families