Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B5R6T3

- PHNX_SALG2

UniProt

B5R6T3 - PHNX_SALG2

Protein

Phosphonoacetaldehyde hydrolase

Gene

phnX

Organism
Salmonella gallinarum (strain 287/91 / NCTC 13346)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (04 Nov 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Involved in phosphonate degradation.UniRule annotation

    Catalytic activityi

    Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotation

    Cofactori

    Binds 1 Mg2+ ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei11 – 111NucleophileUniRule annotation
    Metal bindingi11 – 111MagnesiumUniRule annotation
    Metal bindingi13 – 131Magnesium; via carbonyl oxygenUniRule annotation
    Active sitei53 – 531Schiff-base intermediate with substrateUniRule annotation
    Metal bindingi187 – 1871MagnesiumUniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphonoacetaldehyde hydrolase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. organic phosphonate catabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Ligandi

    Magnesium, Metal-binding, Schiff base

    Enzyme and pathway databases

    BioCyciSENT550538:GJ93-440-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphonoacetaldehyde hydrolaseUniRule annotation (EC:3.11.1.1UniRule annotation)
    Short name:
    PhosphonataseUniRule annotation
    Alternative name(s):
    Phosphonoacetaldehyde phosphonohydrolaseUniRule annotation
    Gene namesi
    Name:phnXUniRule annotation
    Ordered Locus Names:SG0443
    OrganismiSalmonella gallinarum (strain 287/91 / NCTC 13346)
    Taxonomic identifieri550538 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000008321: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 270270Phosphonoacetaldehyde hydrolasePRO_1000144839Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi550538.SG0443.

    Structurei

    3D structure databases

    ProteinModelPortaliB5R6T3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the HAD-like hydrolase superfamily. PhnX family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0637.
    HOGENOMiHOG000049554.
    OMAiGATWEEY.
    OrthoDBiEOG6ZH2FH.

    Family and domain databases

    Gene3Di1.10.150.240. 1 hit.
    3.40.50.1000. 2 hits.
    HAMAPiMF_01375. PhnX.
    InterProiIPR023214. HAD-like_dom.
    IPR006439. HAD-SF_hydro_IA.
    IPR023198. PGP_dom2.
    IPR006323. Phosphonoacetald_hydro.
    [Graphical view]
    PfamiPF13419. HAD_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF56784. SSF56784. 1 hit.
    TIGRFAMsiTIGR01509. HAD-SF-IA-v3. 1 hit.
    TIGR01422. phosphonatase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B5R6T3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMNRIHAVIL DWAGTTVDFG SFAPTQIFVE AFRQAFDVEI TLAEARVPMG    50
    LGKWQHIEAL GKLPAVDARW QAKFGRSMSA ADIDAIYAAF MPLQIAKVVD 100
    FSSPIAGVID TIAALRAEGI KIGSCSGYPR AVMERLVPAA AEHGYRPDHW 150
    VATDDLAAGG RPGPWMALQN VIALGIDAVA HCVKVDDAAL GISEGLNAGM 200
    WTVGLAVSGN EFGATWDAYQ TMSKEDVAVR REHAASKLYA AGAHYVVDSL 250
    ADLSGVIAHI NARLAQGERP 270
    Length:270
    Mass (Da):28,783
    Last modified:November 4, 2008 - v1
    Checksum:i14FC0778071D940E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM933173 Genomic DNA. Translation: CAR36342.1.
    RefSeqiYP_002225544.1. NC_011274.1.

    Genome annotation databases

    EnsemblBacteriaiCAR36342; CAR36342; EBG00000234412.
    PATRICi18499055. VBISalEnt1629_0480.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM933173 Genomic DNA. Translation: CAR36342.1 .
    RefSeqi YP_002225544.1. NC_011274.1.

    3D structure databases

    ProteinModelPortali B5R6T3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 550538.SG0443.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAR36342 ; CAR36342 ; EBG00000234412 .
    PATRICi 18499055. VBISalEnt1629_0480.

    Phylogenomic databases

    eggNOGi COG0637.
    HOGENOMi HOG000049554.
    OMAi GATWEEY.
    OrthoDBi EOG6ZH2FH.

    Enzyme and pathway databases

    BioCyci SENT550538:GJ93-440-MONOMER.

    Family and domain databases

    Gene3Di 1.10.150.240. 1 hit.
    3.40.50.1000. 2 hits.
    HAMAPi MF_01375. PhnX.
    InterProi IPR023214. HAD-like_dom.
    IPR006439. HAD-SF_hydro_IA.
    IPR023198. PGP_dom2.
    IPR006323. Phosphonoacetald_hydro.
    [Graphical view ]
    Pfami PF13419. HAD_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56784. SSF56784. 1 hit.
    TIGRFAMsi TIGR01509. HAD-SF-IA-v3. 1 hit.
    TIGR01422. phosphonatase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 287/91 / NCTC 13346.

    Entry informationi

    Entry nameiPHNX_SALG2
    AccessioniPrimary (citable) accession number: B5R6T3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: November 4, 2008
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3