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B5R6T3

- PHNX_SALG2

UniProt

B5R6T3 - PHNX_SALG2

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Protein

Phosphonoacetaldehyde hydrolase

Gene
phnX, SG0443
Organism
Salmonella gallinarum (strain 287/91 / NCTC 13346)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in phosphonate degradation By similarity.UniRule annotation

Catalytic activityi

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotation

Cofactori

Binds 1 Mg2+ ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei11 – 111Nucleophile By similarity
Metal bindingi11 – 111Magnesium By similarity
Metal bindingi13 – 131Magnesium; via carbonyl oxygen By similarity
Active sitei53 – 531Schiff-base intermediate with substrate By similarity
Metal bindingi187 – 1871Magnesium By similarity

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphonoacetaldehyde hydrolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. organic phosphonate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium, Metal-binding, Schiff base

Enzyme and pathway databases

BioCyciSENT550538:GJ93-440-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphonoacetaldehyde hydrolase (EC:3.11.1.1)
Short name:
Phosphonatase
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolase
Gene namesi
Name:phnX
Ordered Locus Names:SG0443
OrganismiSalmonella gallinarum (strain 287/91 / NCTC 13346)
Taxonomic identifieri550538 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000008321: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 270270Phosphonoacetaldehyde hydrolaseUniRule annotationPRO_1000144839Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi550538.SG0443.

Structurei

3D structure databases

ProteinModelPortaliB5R6T3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0637.
HOGENOMiHOG000049554.
OMAiGATWEEY.
OrthoDBiEOG6ZH2FH.

Family and domain databases

Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPiMF_01375. PhnX.
InterProiIPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view]
PfamiPF13419. HAD_2. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01509. HAD-SF-IA-v3. 1 hit.
TIGR01422. phosphonatase. 1 hit.

Sequencei

Sequence statusi: Complete.

B5R6T3-1 [UniParc]FASTAAdd to Basket

« Hide

MMNRIHAVIL DWAGTTVDFG SFAPTQIFVE AFRQAFDVEI TLAEARVPMG    50
LGKWQHIEAL GKLPAVDARW QAKFGRSMSA ADIDAIYAAF MPLQIAKVVD 100
FSSPIAGVID TIAALRAEGI KIGSCSGYPR AVMERLVPAA AEHGYRPDHW 150
VATDDLAAGG RPGPWMALQN VIALGIDAVA HCVKVDDAAL GISEGLNAGM 200
WTVGLAVSGN EFGATWDAYQ TMSKEDVAVR REHAASKLYA AGAHYVVDSL 250
ADLSGVIAHI NARLAQGERP 270
Length:270
Mass (Da):28,783
Last modified:November 4, 2008 - v1
Checksum:i14FC0778071D940E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM933173 Genomic DNA. Translation: CAR36342.1.
RefSeqiYP_002225544.1. NC_011274.1.

Genome annotation databases

EnsemblBacteriaiCAR36342; CAR36342; EBG00000234412.
PATRICi18499055. VBISalEnt1629_0480.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM933173 Genomic DNA. Translation: CAR36342.1 .
RefSeqi YP_002225544.1. NC_011274.1.

3D structure databases

ProteinModelPortali B5R6T3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 550538.SG0443.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR36342 ; CAR36342 ; EBG00000234412 .
PATRICi 18499055. VBISalEnt1629_0480.

Phylogenomic databases

eggNOGi COG0637.
HOGENOMi HOG000049554.
OMAi GATWEEY.
OrthoDBi EOG6ZH2FH.

Enzyme and pathway databases

BioCyci SENT550538:GJ93-440-MONOMER.

Family and domain databases

Gene3Di 1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPi MF_01375. PhnX.
InterProi IPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view ]
Pfami PF13419. HAD_2. 1 hit.
[Graphical view ]
SUPFAMi SSF56784. SSF56784. 1 hit.
TIGRFAMsi TIGR01509. HAD-SF-IA-v3. 1 hit.
TIGR01422. phosphonatase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 287/91 / NCTC 13346.

Entry informationi

Entry nameiPHNX_SALG2
AccessioniPrimary (citable) accession number: B5R6T3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 4, 2008
Last modified: June 11, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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