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Protein

Phosphonoacetaldehyde hydrolase

Gene

phnX

Organism
Salmonella gallinarum (strain 287/91 / NCTC 13346)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in phosphonate degradation.UniRule annotation

Catalytic activityi

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei11NucleophileUniRule annotation1
Metal bindingi11MagnesiumUniRule annotation1
Metal bindingi13Magnesium; via carbonyl oxygenUniRule annotation1
Active sitei53Schiff-base intermediate with substrateUniRule annotation1
Metal bindingi187MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandMagnesium, Metal-binding, Schiff base

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphonoacetaldehyde hydrolaseUniRule annotation (EC:3.11.1.1UniRule annotation)
Short name:
PhosphonataseUniRule annotation
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolaseUniRule annotation
Gene namesi
Name:phnXUniRule annotation
Ordered Locus Names:SG0443
OrganismiSalmonella gallinarum (strain 287/91 / NCTC 13346)
Taxonomic identifieri550538 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000008321 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001448391 – 270Phosphonoacetaldehyde hydrolaseAdd BLAST270

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB5R6T3
SMRiB5R6T3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. PhnX family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000049554
KOiK05306
OMAiKAVIFDW
OrthoDBiPOG091H05HY

Family and domain databases

CDDicd02586 HAD_PHN, 1 hit
Gene3Di1.10.150.240, 1 hit
3.40.50.1000, 2 hits
HAMAPiMF_01375 PhnX, 1 hit
InterProiView protein in InterPro
IPR036412 HAD-like_sf
IPR006439 HAD-SF_hydro_IA
IPR023214 HAD_sf
IPR023198 PGP-like_dom2
IPR006323 Phosphonoacetald_hydro
SUPFAMiSSF56784 SSF56784, 1 hit
TIGRFAMsiTIGR01509 HAD-SF-IA-v3, 1 hit
TIGR01422 phosphonatase, 1 hit

Sequencei

Sequence statusi: Complete.

B5R6T3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMNRIHAVIL DWAGTTVDFG SFAPTQIFVE AFRQAFDVEI TLAEARVPMG
60 70 80 90 100
LGKWQHIEAL GKLPAVDARW QAKFGRSMSA ADIDAIYAAF MPLQIAKVVD
110 120 130 140 150
FSSPIAGVID TIAALRAEGI KIGSCSGYPR AVMERLVPAA AEHGYRPDHW
160 170 180 190 200
VATDDLAAGG RPGPWMALQN VIALGIDAVA HCVKVDDAAL GISEGLNAGM
210 220 230 240 250
WTVGLAVSGN EFGATWDAYQ TMSKEDVAVR REHAASKLYA AGAHYVVDSL
260 270
ADLSGVIAHI NARLAQGERP
Length:270
Mass (Da):28,783
Last modified:November 4, 2008 - v1
Checksum:i14FC0778071D940E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM933173 Genomic DNA Translation: CAR36342.1

Genome annotation databases

KEGGiseg:SG0443

Similar proteinsi

Entry informationi

Entry nameiPHNX_SALG2
AccessioniPrimary (citable) accession number: B5R6T3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 4, 2008
Last modified: March 28, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health