B5R6Q5 (ACPH_SALG2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acyl carrier protein phosphodiesterase
Short name=ACP phosphodiesterase
EC=3.1.4.14

Gene names

Name:	acpH
Ordered Locus Names:	SG0415

Organism

Salmonella gallinarum (strain 287/91 / NCTC 13346) [Complete proteome] [HAMAP]

Taxonomic identifier

550538 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica I › Salmonella gallinarum

Protein attributes

Sequence length	193 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP By similarity. HAMAP-Rule MF_01950
Catalytic activity	Holo-[acyl-carrier-protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier-protein]. HAMAP-Rule MF_01950
Sequence similarities	Belongs to the AcpH family.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	fatty acid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	[acyl-carrier-protein] phosphodiesterase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 193	193	Acyl carrier protein phosphodiesterase HAMAP-Rule MF_01950		PRO_1000188813

Sequences

	Sequence		Length	Mass (Da)
	B5R6Q5 [UniParc]. Last modified November 4, 2008. Version 1. Checksum: DAC36DC0FA32B84B	FASTA	193	22,917
	10 20 30 40 50 60 MNFLAHLHLA HLADSSLSGN LLADFVRGNP ATHYPPDVVE GIYMHRRIDV MTDNLPEVRE 70 80 90 100 110 120 AREWFRHETR RVAPITLDVM WDHFLSRHWT QISPDFPLQA FVGYAHAQVA TILPDSPPRF 130 140 150 160 170 180 VNLNDYLWSE KWLERYRDMD FIQNVLNGMA NRRPRLDALR DSWYDLDAHY DALEERFWHF 190 YPRMMAQAAR KAL

References

[1]

"Comparative genome analysis of Salmonella enteritidis PT4 and Salmonella gallinarum 287/91 provides insights into evolutionary and host adaptation pathways." Thomson N.R., Clayton D.J., Windhorst D., Vernikos G., Davidson S., Churcher C., Quail M.A., Stevens M., Jones M.A., Watson M., Barron A., Layton A., Pickard D., Kingsley R.A., Bignell A., Clark L., Harris B., Ormond D. , Abdellah Z., Brooks K., Cherevach I., Chillingworth T., Woodward J., Norberczak H., Lord A., Arrowsmith C., Jagels K., Moule S., Mungall K., Saunders M., Whitehead S., Chabalgoity J.A., Maskell D., Humphreys T., Roberts M., Barrow P.A., Dougan G., Parkhill J. Genome Res. 18:1624-1637(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 287/91 / NCTC 13346.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM933173 Genomic DNA. Translation: CAR36314.1.
RefSeq	YP_002225516.1. NC_011274.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	550538.SG0415.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAR36314; CAR36314; SG0415.
GeneID	6922081.
KEGG	seg:SG0415.
PATRIC	18498993. VBISalEnt1629_0449.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG310732.
HOGENOM	HOG000096993.
KO	K08682.
OMA	WLHRQID.
ProtClustDB	PRK10045.
Enzyme and pathway databases
BioCyc	SENT550538:GJ93-412-MONOMER.
Family and domain databases
HAMAP	MF_01950. AcpH.
InterPro	IPR007431. ACP_phosphodiesterase. IPR023491. ACP_phosphodiesterase_gpbac. [Graphical view]
Pfam	PF04336. DUF479. 1 hit. [Graphical view]
PIRSF	PIRSF011489. DUF479. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ACPH_SALG2

Accession

Primary (citable) accession number: B5R6Q5

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	November 4, 2008
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program