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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Salmonella enteritidis PT4 (strain P125109)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciSENT550537:GJFI-85-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:SEN0090
OrganismiSalmonella enteritidis PT4 (strain P125109)
Taxonomic identifieri550537 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 282282Bis(5'-nucleosyl)-tetraphosphatase, symmetricalPRO_1000099332Add
BLAST

Proteomic databases

PRIDEiB5R1S6.

Structurei

3D structure databases

ProteinModelPortaliB5R1S6.
SMRiB5R1S6. Positions 2-268.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000251871.
KOiK01525.
OMAiINAFTRM.
OrthoDBiEOG66B3WP.

Family and domain databases

Gene3Di3.60.21.10. 2 hits.
HAMAPiMF_00199. ApaH.
InterProiIPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFiPIRSF000903. B5n-ttraPtase_sm. 1 hit.
SUPFAMiSSF56300. SSF56300. 1 hit.
TIGRFAMsiTIGR00668. apaH. 1 hit.

Sequencei

Sequence statusi: Complete.

B5R1S6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATYLIGDVH GCYDELIALL QQVEFTPDTD TLWLTGDLVA RGPGSLDVLR
60 70 80 90 100
YVKSLGNSVR LVLGNHDLHL LAVFAGISRN KPKDRLTPLL EAPDADELLN
110 120 130 140 150
WLRRQPLLQV DEEKKLVMAH AGITPQWDLQ TAKECARDVE AVLSSDSYPF
160 170 180 190 200
FLDAMYGDMP NNWSPELSGL ARLRFITNAF TRMRYCFPNG QLDMYSKASP
210 220 230 240 250
ENAPAPLKPW FAIPGPVSEA YSIAFGHWAS LEGKGTPEGI YALDTGCCWG
260 270 280
GELTCLRWED KQYFVQPSNR QMDMGEGEAV NA
Length:282
Mass (Da):31,431
Last modified:November 4, 2008 - v1
Checksum:iB5B701E39CA7869E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM933172 Genomic DNA. Translation: CAR31677.1.
RefSeqiWP_000257211.1. NC_011294.1.

Genome annotation databases

EnsemblBacteriaiCAR31677; CAR31677; SEN0090.
KEGGiset:SEN0090.
PATRICi32330555. VBISalEnt14964_0089.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM933172 Genomic DNA. Translation: CAR31677.1.
RefSeqiWP_000257211.1. NC_011294.1.

3D structure databases

ProteinModelPortaliB5R1S6.
SMRiB5R1S6. Positions 2-268.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB5R1S6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAR31677; CAR31677; SEN0090.
KEGGiset:SEN0090.
PATRICi32330555. VBISalEnt14964_0089.

Phylogenomic databases

HOGENOMiHOG000251871.
KOiK01525.
OMAiINAFTRM.
OrthoDBiEOG66B3WP.

Enzyme and pathway databases

BioCyciSENT550537:GJFI-85-MONOMER.

Family and domain databases

Gene3Di3.60.21.10. 2 hits.
HAMAPiMF_00199. ApaH.
InterProiIPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFiPIRSF000903. B5n-ttraPtase_sm. 1 hit.
SUPFAMiSSF56300. SSF56300. 1 hit.
TIGRFAMsiTIGR00668. apaH. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: P125109.

Entry informationi

Entry nameiAPAH_SALEP
AccessioniPrimary (citable) accession number: B5R1S6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 4, 2008
Last modified: November 11, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.