Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chorismate pyruvate-lyase

Gene

ubiC

Organism
Salmonella enteritidis PT4 (strain P125109)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.UniRule annotation

Catalytic activityi

Chorismate = 4-hydroxybenzoate + pyruvate.UniRule annotation

Pathwayi: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei35 – 351Substrate; via amide nitrogenUniRule annotation
Binding sitei77 – 771SubstrateUniRule annotation
Binding sitei115 – 1151Substrate; via amide nitrogenUniRule annotation
Binding sitei156 – 1561SubstrateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Ubiquinone biosynthesis

Keywords - Ligandi

Pyruvate

Enzyme and pathway databases

BioCyciSENT550537:GJFI-4069-MONOMER.
UniPathwayiUPA00232.

Names & Taxonomyi

Protein namesi
Recommended name:
Chorismate pyruvate-lyaseUniRule annotation (EC:4.1.3.40UniRule annotation)
Short name:
CLUniRule annotation
Short name:
CPLUniRule annotation
Gene namesi
Name:ubiCUniRule annotation
Ordered Locus Names:SEN4002
OrganismiSalmonella enteritidis PT4 (strain P125109)
Taxonomic identifieri550537 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 165165Chorismate pyruvate-lyasePRO_1000186533Add
BLAST

Proteomic databases

PRIDEiB5QZ58.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB5QZ58.
SMRiB5QZ58. Positions 2-165.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UbiC family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000137785.
KOiK03181.
OMAiELWGRRS.

Family and domain databases

Gene3Di3.40.1410.10. 1 hit.
HAMAPiMF_01632. UbiC. 1 hit.
InterProiIPR007440. Chorismate--pyruvate_lyase.
IPR028978. Chorismate_lyase_/UTRA_dom.
[Graphical view]
PfamiPF04345. Chor_lyase. 1 hit.
[Graphical view]
SUPFAMiSSF64288. SSF64288. 1 hit.

Sequencei

Sequence statusi: Complete.

B5QZ58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHPALTQLR ALRYFDAIPA LEPHLLDWLL LEDSMTKRFE QQGKRVSVTL
60 70 80 90 100
IREAFVGQSE VEEASGLLPS ESRYWLREIL LCADGEPWLA GRTVVPESTL
110 120 130 140 150
CGPEQVLQHL GKTPLGRYLF TSSTLTRDFI EIGRDATLWG RRSRLRLSGK
160
PLLLTELFLP ASPLY
Length:165
Mass (Da):18,720
Last modified:November 4, 2008 - v1
Checksum:i98658AEEC6EF54D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM933172 Genomic DNA. Translation: CAR35566.1.
RefSeqiWP_000019219.1. NC_011294.1.

Genome annotation databases

EnsemblBacteriaiCAR35566; CAR35566; SEN4002.
KEGGiset:SEN4002.
PATRICi32338727. VBISalEnt14964_4079.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM933172 Genomic DNA. Translation: CAR35566.1.
RefSeqiWP_000019219.1. NC_011294.1.

3D structure databases

ProteinModelPortaliB5QZ58.
SMRiB5QZ58. Positions 2-165.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB5QZ58.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAR35566; CAR35566; SEN4002.
KEGGiset:SEN4002.
PATRICi32338727. VBISalEnt14964_4079.

Phylogenomic databases

HOGENOMiHOG000137785.
KOiK03181.
OMAiELWGRRS.

Enzyme and pathway databases

UniPathwayiUPA00232.
BioCyciSENT550537:GJFI-4069-MONOMER.

Family and domain databases

Gene3Di3.40.1410.10. 1 hit.
HAMAPiMF_01632. UbiC. 1 hit.
InterProiIPR007440. Chorismate--pyruvate_lyase.
IPR028978. Chorismate_lyase_/UTRA_dom.
[Graphical view]
PfamiPF04345. Chor_lyase. 1 hit.
[Graphical view]
SUPFAMiSSF64288. SSF64288. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUBIC_SALEP
AccessioniPrimary (citable) accession number: B5QZ58
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: November 4, 2008
Last modified: September 7, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.