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B5QXN6

- B5QXN6_SALEP

UniProt

B5QXN6 - B5QXN6_SALEP

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Protein
Alanine racemase
Gene
SEN3897
Organism
Salmonella enteritidis PT4 (strain P125109)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei42 – 421Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei141 – 1411Substrate By similarityUniRule annotation
Active sitei262 – 2621Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei310 – 3101Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotations

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciSENT550537:GJFI-3961-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:SEN3897Imported
OrganismiSalmonella enteritidis PT4 (strain P125109)Imported
Taxonomic identifieri550537 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000000613: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei42 – 421N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi550537.SEN3897.

Structurei

3D structure databases

ProteinModelPortaliB5QXN6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031445.
OMAiPAGVCWR.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5QXN6-1 [UniParc]FASTAAdd to Basket

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MMKLAEIQAA CGVLCVDLAA VVDNYQTLAR HVAPAQCGAV LKANGYGLGA    50
EAIAPALYAA NCRIFFVAQL SEGVALRKIL SADAMVVLLN GVMPQAMPLC 100
CAQQITPLLN SVDQVMAWLA LQEARSQRRP VLIQLDSGMS RLGVTPEQLA 150
RLAAIFRQRG WAAPDYIISH LANADRPDHA LNVYQHTLLQ QAKEAFPTSR 200
YSLANSCGMF LHPAWREDLC RPGVALFGVA QPWFSTPLKP AFTLTLSILR 250
VQDVPVGTPI GYGSTVTTTR PLRIATVSAG YADGIPRNLR PPAGVCWRGV 300
RLPVLGRVCM DSFMVDASAI MPTPGDVVEF IGVSQTLEEV AAACDTIPYE 350
IMTRLGGRFR RIMQPAEA 368
Length:368
Mass (Da):39,741
Last modified:November 4, 2008 - v1
Checksum:i70B464CD639C7DEC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM933172 Genomic DNA. Translation: CAR35471.1.
RefSeqiYP_002245945.1. NC_011294.1.

Genome annotation databases

EnsemblBacteriaiCAR35471; CAR35471; SEN3897.
PATRICi32338508. VBISalEnt14964_3983.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM933172 Genomic DNA. Translation: CAR35471.1 .
RefSeqi YP_002245945.1. NC_011294.1.

3D structure databases

ProteinModelPortali B5QXN6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 550537.SEN3897.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR35471 ; CAR35471 ; SEN3897 .
PATRICi 32338508. VBISalEnt14964_3983.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031445.
OMAi PAGVCWR.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci SENT550537:GJFI-3961-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: P125109Imported.

Entry informationi

Entry nameiB5QXN6_SALEP
AccessioniPrimary (citable) accession number: B5QXN6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 4, 2008
Last sequence update: November 4, 2008
Last modified: July 9, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi