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Protein

Ribose-5-phosphate isomerase A

Gene

rpiA

Organism
Salmonella enteritidis PT4 (strain P125109)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.UniRule annotation

Catalytic activityi

D-ribose 5-phosphate = D-ribulose 5-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei103 – 1031Proton acceptorUniRule annotation
Binding sitei121 – 1211SubstrateUniRule annotation

GO - Molecular functioni

  1. ribose-5-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt, non-oxidative branch Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciSENT550537:GJFI-2947-MONOMER.
UniPathwayiUPA00115; UER00412.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribose-5-phosphate isomerase AUniRule annotation (EC:5.3.1.6UniRule annotation)
Alternative name(s):
Phosphoriboisomerase AUniRule annotation
Short name:
PRIUniRule annotation
Gene namesi
Name:rpiAUniRule annotation
Ordered Locus Names:SEN2906
OrganismiSalmonella enteritidis PT4 (strain P125109)
Taxonomic identifieri550537 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000000613: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 219219Ribose-5-phosphate isomerase APRO_1000097690Add
BLAST

Proteomic databases

PRIDEiB5QXJ0.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi550537.SEN2906.

Structurei

3D structure databases

ProteinModelPortaliB5QXJ0.
SMRiB5QXJ0. Positions 1-219.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni28 – 314Substrate bindingUniRule annotation
Regioni81 – 844Substrate bindingUniRule annotation
Regioni94 – 974Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the ribose 5-phosphate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0120.
HOGENOMiHOG000276368.
OMAiGACHVQE.
OrthoDBiEOG67MF61.

Family and domain databases

HAMAPiMF_00170. Rib_5P_isom_A.
InterProiIPR004788. Ribose5P_isomerase_typA.
IPR020672. Ribose5P_isomerase_typA_subgr.
[Graphical view]
PANTHERiPTHR11934. PTHR11934. 1 hit.
PfamiPF06026. Rib_5-P_isom_A. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00021. rpiA. 1 hit.

Sequencei

Sequence statusi: Complete.

B5QXJ0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTQDELKKAV GWAALQYVQP GTIVGVGTGS TAAHFIDALG TMKGQIEGAV
60 70 80 90 100
SSSDASTEKL KGLGIHVFDL NEVDSLGIYV DGADEINGHM QMIKGGGAAL
110 120 130 140 150
TREKIIASVA EKFICIADAS KQVDILGKFP LPVEVIPMAR SAVARQLVKL
160 170 180 190 200
GGRPEYRQNV VTDNGNVILD VYGMEILDPI ALENAINAIP GVVTVGLFAN
210
RGADVALIGT PDGVKTIVK
Length:219
Mass (Da):22,895
Last modified:November 4, 2008 - v1
Checksum:iFEA022A02971BF3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM933172 Genomic DNA. Translation: CAR34484.1.
RefSeqiYP_002244977.1. NC_011294.1.

Genome annotation databases

EnsemblBacteriaiCAR34484; CAR34484; SEN2906.
PATRICi32336409. VBISalEnt14964_2961.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM933172 Genomic DNA. Translation: CAR34484.1.
RefSeqiYP_002244977.1. NC_011294.1.

3D structure databases

ProteinModelPortaliB5QXJ0.
SMRiB5QXJ0. Positions 1-219.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi550537.SEN2906.

Proteomic databases

PRIDEiB5QXJ0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAR34484; CAR34484; SEN2906.
PATRICi32336409. VBISalEnt14964_2961.

Phylogenomic databases

eggNOGiCOG0120.
HOGENOMiHOG000276368.
OMAiGACHVQE.
OrthoDBiEOG67MF61.

Enzyme and pathway databases

UniPathwayiUPA00115; UER00412.
BioCyciSENT550537:GJFI-2947-MONOMER.

Family and domain databases

HAMAPiMF_00170. Rib_5P_isom_A.
InterProiIPR004788. Ribose5P_isomerase_typA.
IPR020672. Ribose5P_isomerase_typA_subgr.
[Graphical view]
PANTHERiPTHR11934. PTHR11934. 1 hit.
PfamiPF06026. Rib_5-P_isom_A. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00021. rpiA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: P125109.

Entry informationi

Entry nameiRPIA_SALEP
AccessioniPrimary (citable) accession number: B5QXJ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 4, 2008
Last modified: January 7, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.