B5MV62 (B5MV62_SALET) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
L-arabinose isomerase HAMAP MF_00519
EC=5.3.1.4 HAMAP MF_00519

Gene names

Name:	araA HAMAP MF_00519
ORF Names:	SeI_A4427 EMBL EDZ18267.1

Organism

Salmonella enterica subsp. enterica serovar 4,[5],12:i:- str. CVM23701 EMBL EDZ18267.1

Taxonomic identifier

440534 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella enterica subsp. enterica serovar 4,[5],12:i:-

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity. HAMAP MF_00519 SAAS SAAS003762
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519 SAAS SAAS003762
Cofactor	Binds 1 manganese ion per subunit By similarity. HAMAP MF_00519 SAAS SAAS003762
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519 SAAS SAAS003762
Subunit structure	Homohexamer By similarity. HAMAP MF_00519
Sequence similarities	Belongs to the arabinose isomerase family. HAMAP MF_00519
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Ontologies

Keywords
Biological process	Arabinose catabolism HAMAP MF_00519 SAAS SAAS003762 Carbohydrate metabolism
Ligand	Manganese HAMAP MF_00519 SAAS SAAS003762 Metal-binding HAMAP MF_00519 SAAS SAAS003762
Molecular function	Isomerase HAMAP MF_00519 SAAS SAAS003762 EMBL EDZ18267.1
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: HAMAP fucose metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: HAMAP L-fucose isomerase activity Inferred from electronic annotation. Source: InterPro manganese ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	306	1	Manganese By similarity HAMAP MF_00519
	Metal binding	333	1	Manganese By similarity HAMAP MF_00519
	Metal binding	350	1	Manganese By similarity HAMAP MF_00519
	Metal binding	450	1	Manganese By similarity HAMAP MF_00519

Sequences

	Sequence		Length	Mass (Da)
	B5MV62 [UniParc]. Last modified November 4, 2008. Version 1. Checksum: 97112E535F7EC2BF	FASTA	500	55,892
	10 20 30 40 50 60 MTIFDNYEVW FVIGSQHLYG AETLRQVTQH AEHVVNALNT EAKLPCKLVL KPLGTSPDEI 70 80 90 100 110 120 TAICRDANYD DRCAGLVVWL HTFSPAKMWI NGLSILNKPL LQFHTQFNAA LPWDSIDMDF 130 140 150 160 170 180 MNLNQTAHGG REFGFIGARM RQQHAVVTGH WQDKEAHTRI GAWMRQAVSK QDTRQLKVCR 190 200 210 220 230 240 FGDNMREVAV TDGDKVAAQI KFGFSVNTWA VGDLVQVVNS IGDGDINALI DEYESSYTLT 250 260 270 280 290 300 PATQIHGDKR QNVREAARIE LGMKRFLEQG GFHAFTTTFE DLHGLKQLPG LAVQRLMQQG 310 320 330 340 350 360 YGFAGEGDWK TAALLRIMKV MSTGLQGGTS FMEDYTYHFE KGNDLVLGSH MLEVCPSIAV 370 380 390 400 410 420 EEKPILDVQH LGIGGKEDPA RLIFNTQTGP AIVASLIDLG DRYRLLVNCI DTVKTPHSLP 430 440 450 460 470 480 KLPVANALWK AQPDLPTASE AWILAGGAHH TVFSHALDLN DMRQFAEIHD IEIAVIDNDT 490 500 HLPAFKDALR WNEVYYGFKR

References

[1]	"Comparative genomics of 28 Salmonella enterica isolates: evidence for CRISPR-mediated adaptive sublineage evolution." Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G., Leclerc J.E., Ravel J., Cebula T.A. J. Bacteriol. 193:3556-3568(2011) [PubMed: 21602358] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: CVM23701 EMBL EDZ18267.1.
[2]	Rosovitz M.J., McDermott P., White D., LeClerc J.E., Mammel M.K., Cebula T.A., Ravel J. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: CVM23701 EMBL EDZ18267.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ABAO01000001 Genomic DNA. Translation: EDZ18267.1.
3D structure databases
ProteinModelPortal	B5MV62.
SMR	B5MV62. Positions 1-498.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	27920874. VBISalEnt101080_0156.
Family and domain databases
HAMAP	MF_00519. Arabinose_Isome. [Tree]
InterPro	IPR024664. Ara_Isoase_C. IPR004216. Fuc/Ara_isomerase_C. IPR009015. Fucose_isomerase_N/cen. IPR003762. Lara_isomerase. [Graphical view]
Pfam	PF11762. Arabinose_Iso_C. 1 hit. PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF50443. Fuc_isomerase_C. 1 hit. SSF53743. Fuc_isomerase_N. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B5MV62_SALET

Accession

Primary (citable) accession number: B5MV62

Entry history

Integrated into UniProtKB/TrEMBL:	November 4, 2008
Last sequence update:	November 4, 2008
Last modified:	January 25, 2012
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)