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Protein
Submitted name:

Sushi, nidogen and EGF-like domain-containing protein 1

Gene

SNED1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Sushi, nidogen and EGF-like domain-containing protein 1Imported
Gene namesi
Name:SNED1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000162804.13
HGNCiHGNC:24696 SNED1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000162804

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi52 ↔ 61PROSITE-ProRule annotation
Disulfide bondi90 ↔ 99PROSITE-ProRule annotation
Disulfide bondi128 ↔ 137PROSITE-ProRule annotation
Disulfide bondi535 ↔ 544PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PeptideAtlasiB5MEF5
PRIDEiB5MEF5

Expressioni

Gene expression databases

BgeeiENSG00000162804
ExpressionAtlasiB5MEF5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliB5MEF5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 62EGF-likeInterPro annotationAdd BLAST37
Domaini64 – 100EGF-likeInterPro annotationAdd BLAST37
Domaini102 – 138EGF-likeInterPro annotationAdd BLAST37
Domaini143 – 241Fibronectin type-IIIInterPro annotationAdd BLAST99
Domaini242 – 340Fibronectin type-IIIInterPro annotationAdd BLAST99
Domaini341 – 435Fibronectin type-IIIInterPro annotationAdd BLAST95
Domaini509 – 545EGF-likeInterPro annotationAdd BLAST37

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00810000125346
HOGENOMiHOG000081748
HOVERGENiHBG108495

Family and domain databases

CDDicd00063 FN3, 3 hits
Gene3Di2.60.40.10, 3 hits
InterProiView protein in InterPro
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR009030 Growth_fac_rcpt_cys_sf
IPR013783 Ig-like_fold
PfamiView protein in Pfam
PF00008 EGF, 3 hits
PF00041 fn3, 3 hits
SMARTiView protein in SMART
SM00181 EGF, 4 hits
SM00179 EGF_CA, 4 hits
SM00060 FN3, 3 hits
SUPFAMiSSF49265 SSF49265, 2 hits
SSF57184 SSF57184, 1 hit
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 1 hit
PS00022 EGF_1, 4 hits
PS01186 EGF_2, 2 hits
PS50026 EGF_3, 4 hits
PS50853 FN3, 3 hits

Sequencei

Sequence statusi: Complete.

B5MEF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHGILGACGR LRLEPATPLT PLLCAERDEC RAHPCRNGGS CRNLPGAYVC
60 70 80 90 100
RCPAGFVGVH CETEVDACDS SPCQHGGRCE SGGGAYLCVC PESFFGYHCE
110 120 130 140 150
TVSDPCFSSP CGGRGYCLAS NGSHSCTCKV GYTGEDCAKE LFPPTALKME
160 170 180 190 200
RVEESGVSIS WNPPNGPAAR QMLDGYAVTY VSSDGSYRRT DFVDRTRSSH
210 220 230 240 250
QLQALAAGRA YNISVFSVKR NSNNKNDISR PAVLLARTRP RPVEGFEVTN
260 270 280 290 300
VTASTISVQW ALHRIRHATV SGVRVSIRHP EALRDQATDV DRSVDRFTFR
310 320 330 340 350
ALLPGKRYTI QLTTLSGLRG EEHPTESLAT APTHVWTRPL PPANLTAARV
360 370 380 390 400
TATSAHVVWD APTPGSLLEA YVINVTTSQS TKSRYVPNGK LASYTVRDLL
410 420 430 440 450
PGRRYQLSVI AVQSTELGPQ HSEPAHLYII TSPRDGADRR WHQGGHHPRV
460 470 480 490 500
LKNRPPPARL PELRLLNDHS APETPTQPPR FSELVDGRGR VSARFGGSPS
510 520 530 540 550
KAATVRSHVP GNCSENPCQN GGTCVPGADA HSCDCGPGFK GRRCELACIK
560 570 580 590
VSRPCTRLFS ETKAFPVWEG GVCHHVYKRV YRVHQDICFK ESCESTSLK
Length:599
Mass (Da):65,224
Last modified:October 29, 2014 - v3
Checksum:iEED0CE8128FFE0BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005237 Genomic DNA No translation available.
AC093585 Genomic DNA No translation available.
AC104809 Genomic DNA No translation available.
KF510803 Genomic DNA No translation available.
KF510805 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000342631; ENSP00000342992; ENSG00000162804
UCSCiuc061ukp.1 human

Similar proteinsi

Entry informationi

Entry nameiB5MEF5_HUMAN
AccessioniPrimary (citable) accession number: B5MEF5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 14, 2008
Last sequence update: October 29, 2014
Last modified: March 28, 2018
This is version 85 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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