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B5MEF5

- B5MEF5_HUMAN

UniProt

B5MEF5 - B5MEF5_HUMAN

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Protein
Submitted name: Sushi, nidogen and EGF-like domain-containing protein 1
Gene
SNED1
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro

GO - Biological processi

  1. cell-matrix adhesion Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Sushi, nidogen and EGF-like domain-containing protein 1Imported
Gene namesi
Name:SNED1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:24696. SNED1.

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Proteomic databases

PRIDEiB5MEF5.

Expressioni

Gene expression databases

ArrayExpressiB5MEF5.
BgeeiB5MEF5.

Structurei

3D structure databases

ProteinModelPortaliB5MEF5.
SMRiB5MEF5. Positions 273-696, 753-1191, 1278-1311.

Family & Domainsi

Keywords - Domaini

EGF-like domainUniRule annotationSAAS annotations, RepeatSAAS annotations, SushiSAAS annotations

Phylogenomic databases

HOGENOMiHOG000081748.
HOVERGENiHBG108495.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
InterProiIPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR003961. Fibronectin_type3.
IPR003645. Fol_N.
IPR009030. Growth_fac_rcpt_N_dom.
IPR013783. Ig-like_fold.
IPR003886. Nidogen_extracell_dom.
IPR000436. Sushi_SCR_CCP.
[Graphical view]
PfamiPF00008. EGF. 11 hits.
PF00041. fn3. 3 hits.
PF12661. hEGF. 2 hits.
PF06119. NIDO. 1 hit.
[Graphical view]
SMARTiSM00032. CCP. 1 hit.
SM00181. EGF. 10 hits.
SM00179. EGF_CA. 5 hits.
SM00060. FN3. 3 hits.
SM00274. FOLN. 2 hits.
SM00539. NIDO. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 2 hits.
SSF57184. SSF57184. 1 hit.
SSF57535. SSF57535. 1 hit.
PROSITEiPS00010. ASX_HYDROXYL. 5 hits.
PS00022. EGF_1. 15 hits.
PS01186. EGF_2. 13 hits.
PS50026. EGF_3. 15 hits.
PS01187. EGF_CA. 3 hits.
PS50853. FN3. 3 hits.
PS51220. NIDO. 1 hit.
PS50923. SUSHI. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5MEF5-1 [UniParc]FASTAAdd to Basket

« Hide

MRHGVAWALL VAAALGLGAR GVRGAVALAD FYPFGAERGD AVTPKQDDGG     50
SGLRPLSVPF PFFGAEHSGL YVNNNGIISF LKEVSQFTPV AFPIAKDRCV 100
VAAFWADVDN RRAGDVYYRE ATDPAMLRRA TEDVRHYFPE LLDFNATWVF 150
VATWYRVTFF GGSSSSPVNT FQTVLITDGK LSFTIFNYES IVWTTGTHAS 200
SGGNATGLGG IAAQAGFNAG DGQRYFSIPG SRTADMAEVE TTTNVGVPGR 250
WAFRIDDAQV RVGGCGHTTS VCLALRPCLN GGKCIDDCVT GNPSYTCSCL 300
SGFTGRRCHL DVNECASQPC QNGGTCTHGI NSFRCQCPAG FGGPTCETAQ 350
SPCDTKECQH GGQCQVENGS AVCVCQAGYT GAACEMDVDD CSPDPCLNGG 400
SCVDLVGNYT CLCAEPFKGL RCETGDHPVP DACLSAPCHN GGTCVDADQG 450
YVCECPEGFM GLDCRERVPD DCECRNGGRC LGANTTLCQC PLGFFGLLCE 500
FEITAMPCNM NTQCPDGGYC MEHGGSYLCV CHTDHNASHS LPSPCDSDPC 550
FNGGSCDAHD DSYTCECPRG FHGKHCEKAR PHLCSSGPCR NGGTCKEAGG 600
EYHCSCPYRF TGRHCEIGKP DSCASGPCHN GGTCFHYIGK YKCDCPPGFS 650
GRHCEIAPSP CFRSPCVNGG TCEDRDTDFF CHCQAGYMGR RCQAEVDCGP 700
PEEVKHATLR FNGTRLGAVA LYACDRGYSL SAPSRIRVCQ PHGVWSEPPQ 750
CLEIDECRSQ PCLHGGSCQD RVAGYLCLCS TGYEGAHCEL ERDECRAHPC 800
RNGGSCRNLP GAYVCRCPAG FVGVHCETEV DACDSSPCQH GGRCESGGGA 850
YLCVCPESFF GYHCETVSDP CFSSPCGGRG YCLASNGSHS CTCKVGYTGE 900
DCAKELFPPT ALKMERVEES GVSISWNPPN GPAARQMLDG YAVTYVSSDG 950
SYRRTDFVDR TRSSHQLQAL AAGRAYNISV FSVKRNSNNK NDISRPAVLL 1000
ARTRPRPVEG FEVTNVTAST ISVQWALHRI RHATVSGVRV SIRHPEALRD 1050
QATDVDRSVD RFTFRALLPG KRYTIQLTTL SGLRGEEHPT ESLATAPTHV 1100
WTRPLPPANL TAARVTATSA HVVWDAPTPG SLLEAYVINV TTSQSTKSRY 1150
VPNGKLASYT VRDLLPGRRY QLSVIAVQST ELGPQHSEPA HLYIITSPRD 1200
GADRRWHQGG HHPRVLKNRP PPARLPELRL LNDHSAPETP TQPPRFSELV 1250
DGRGRVSARF GGSPSKAATV RSHVPGNCSE NPCQNGGTCV PGADAHSCDC 1300
GPGFKGRRCE LACIKVSRPC TRLFSETKAF PVWEGGVCHH VYKRVYRVHQ 1350
DICFKESCES TSLKKTPNRK QSKSQTLEKS 1380
Length:1,380
Mass (Da):148,699
Last modified:November 3, 2009 - v2
Checksum:i2F18B76D79C7D295
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005237 Genomic DNA. No translation available.
AC093585 Genomic DNA. No translation available.
AC104809 Genomic DNA. No translation available.
RefSeqiXP_006712469.1. XM_006712406.1.
UniGeneiHs.471834.

Genome annotation databases

EnsembliENST00000342631; ENSP00000342992; ENSG00000162804.
GeneIDi25992.
KEGGihsa:25992.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005237 Genomic DNA. No translation available.
AC093585 Genomic DNA. No translation available.
AC104809 Genomic DNA. No translation available.
RefSeqi XP_006712469.1. XM_006712406.1.
UniGenei Hs.471834.

3D structure databases

ProteinModelPortali B5MEF5.
SMRi B5MEF5. Positions 273-696, 753-1191, 1278-1311.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B5MEF5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000342631 ; ENSP00000342992 ; ENSG00000162804 .
GeneIDi 25992.
KEGGi hsa:25992.

Organism-specific databases

CTDi 25992.
HGNCi HGNC:24696. SNED1.
GenAtlasi Search...

Phylogenomic databases

HOGENOMi HOG000081748.
HOVERGENi HBG108495.

Miscellaneous databases

NextBioi 35478263.

Gene expression databases

ArrayExpressi B5MEF5.
Bgeei B5MEF5.

Family and domain databases

Gene3Di 2.60.40.10. 3 hits.
InterProi IPR000742. EG-like_dom.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR003961. Fibronectin_type3.
IPR003645. Fol_N.
IPR009030. Growth_fac_rcpt_N_dom.
IPR013783. Ig-like_fold.
IPR003886. Nidogen_extracell_dom.
IPR000436. Sushi_SCR_CCP.
[Graphical view ]
Pfami PF00008. EGF. 11 hits.
PF00041. fn3. 3 hits.
PF12661. hEGF. 2 hits.
PF06119. NIDO. 1 hit.
[Graphical view ]
SMARTi SM00032. CCP. 1 hit.
SM00181. EGF. 10 hits.
SM00179. EGF_CA. 5 hits.
SM00060. FN3. 3 hits.
SM00274. FOLN. 2 hits.
SM00539. NIDO. 1 hit.
[Graphical view ]
SUPFAMi SSF49265. SSF49265. 2 hits.
SSF57184. SSF57184. 1 hit.
SSF57535. SSF57535. 1 hit.
PROSITEi PS00010. ASX_HYDROXYL. 5 hits.
PS00022. EGF_1. 15 hits.
PS01186. EGF_2. 13 hits.
PS50026. EGF_3. 15 hits.
PS01187. EGF_CA. 3 hits.
PS50853. FN3. 3 hits.
PS51220. NIDO. 1 hit.
PS50923. SUSHI. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiB5MEF5_HUMAN
AccessioniPrimary (citable) accession number: B5MEF5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 14, 2008
Last sequence update: November 3, 2009
Last modified: September 3, 2014
This is version 53 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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