B5MEF5 (B5MEF5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Sushi, nidogen and EGF-like domain-containing protein 1 Ensembl ENSP00000342992

Gene names

Name:

SNED1 Ensembl ENSP00000342992

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000342992

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1380 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000342992

Ontologies

Keywords
Domain	EGF-like domain RuleBase RU000459 SAAS SAAS000436 Sushi SAAS SAAS000436
PTM	Disulfide bond SAAS SAAS000436
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell-matrix adhesion Inferred from electronic annotation. Source: InterPro
Molecular_function	calcium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B5MEF5 [UniParc]. Last modified November 3, 2009. Version 2. Checksum: 2F18B76D79C7D295	FASTA	1,380	148,699
	10 20 30 40 50 60 MRHGVAWALL VAAALGLGAR GVRGAVALAD FYPFGAERGD AVTPKQDDGG SGLRPLSVPF 70 80 90 100 110 120 PFFGAEHSGL YVNNNGIISF LKEVSQFTPV AFPIAKDRCV VAAFWADVDN RRAGDVYYRE 130 140 150 160 170 180 ATDPAMLRRA TEDVRHYFPE LLDFNATWVF VATWYRVTFF GGSSSSPVNT FQTVLITDGK 190 200 210 220 230 240 LSFTIFNYES IVWTTGTHAS SGGNATGLGG IAAQAGFNAG DGQRYFSIPG SRTADMAEVE 250 260 270 280 290 300 TTTNVGVPGR WAFRIDDAQV RVGGCGHTTS VCLALRPCLN GGKCIDDCVT GNPSYTCSCL 310 320 330 340 350 360 SGFTGRRCHL DVNECASQPC QNGGTCTHGI NSFRCQCPAG FGGPTCETAQ SPCDTKECQH 370 380 390 400 410 420 GGQCQVENGS AVCVCQAGYT GAACEMDVDD CSPDPCLNGG SCVDLVGNYT CLCAEPFKGL 430 440 450 460 470 480 RCETGDHPVP DACLSAPCHN GGTCVDADQG YVCECPEGFM GLDCRERVPD DCECRNGGRC 490 500 510 520 530 540 LGANTTLCQC PLGFFGLLCE FEITAMPCNM NTQCPDGGYC MEHGGSYLCV CHTDHNASHS 550 560 570 580 590 600 LPSPCDSDPC FNGGSCDAHD DSYTCECPRG FHGKHCEKAR PHLCSSGPCR NGGTCKEAGG 610 620 630 640 650 660 EYHCSCPYRF TGRHCEIGKP DSCASGPCHN GGTCFHYIGK YKCDCPPGFS GRHCEIAPSP 670 680 690 700 710 720 CFRSPCVNGG TCEDRDTDFF CHCQAGYMGR RCQAEVDCGP PEEVKHATLR FNGTRLGAVA 730 740 750 760 770 780 LYACDRGYSL SAPSRIRVCQ PHGVWSEPPQ CLEIDECRSQ PCLHGGSCQD RVAGYLCLCS 790 800 810 820 830 840 TGYEGAHCEL ERDECRAHPC RNGGSCRNLP GAYVCRCPAG FVGVHCETEV DACDSSPCQH 850 860 870 880 890 900 GGRCESGGGA YLCVCPESFF GYHCETVSDP CFSSPCGGRG YCLASNGSHS CTCKVGYTGE 910 920 930 940 950 960 DCAKELFPPT ALKMERVEES GVSISWNPPN GPAARQMLDG YAVTYVSSDG SYRRTDFVDR 970 980 990 1000 1010 1020 TRSSHQLQAL AAGRAYNISV FSVKRNSNNK NDISRPAVLL ARTRPRPVEG FEVTNVTAST 1030 1040 1050 1060 1070 1080 ISVQWALHRI RHATVSGVRV SIRHPEALRD QATDVDRSVD RFTFRALLPG KRYTIQLTTL 1090 1100 1110 1120 1130 1140 SGLRGEEHPT ESLATAPTHV WTRPLPPANL TAARVTATSA HVVWDAPTPG SLLEAYVINV 1150 1160 1170 1180 1190 1200 TTSQSTKSRY VPNGKLASYT VRDLLPGRRY QLSVIAVQST ELGPQHSEPA HLYIITSPRD 1210 1220 1230 1240 1250 1260 GADRRWHQGG HHPRVLKNRP PPARLPELRL LNDHSAPETP TQPPRFSELV DGRGRVSARF 1270 1280 1290 1300 1310 1320 GGSPSKAATV RSHVPGNCSE NPCQNGGTCV PGADAHSCDC GPGFKGRRCE LACIKVSRPC 1330 1340 1350 1360 1370 1380 TRLFSETKAF PVWEGGVCHH VYKRVYRVHQ DICFKESCES TSLKKTPNRK QSKSQTLEKS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K. Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC005237 Genomic DNA. No translation available. AC093585 Genomic DNA. No translation available. AC104809 Genomic DNA. No translation available.
IPI	IPI00152789.
3D structure databases
ProteinModelPortal	B5MEF5.
SMR	B5MEF5. Positions 275-696, 753-1226, 1276-1310.
ModBase	Search...
Protein-protein interaction databases
STRING	B5MEF5.
Proteomic databases
PRIDE	B5MEF5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000342631; ENSP00000342992; ENSG00000162804.
Organism-specific databases
HGNC	HGNC:24696. SNED1.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000081748.
HOVERGEN	HBG108495.
Gene expression databases
ArrayExpress	B5MEF5.
Bgee	B5MEF5.
Family and domain databases
Gene3D	2.60.40.10. 3 hits.
InterPro	IPR000742. EG-like_dom. IPR001881. EGF-like_Ca-bd. IPR013032. EGF-like_CS. IPR000152. EGF-type_Asp/Asn_hydroxyl_site. IPR018097. EGF_Ca-bd_CS. IPR003961. Fibronectin_type3. IPR003645. Fol_N. IPR013783. Ig-like_fold. IPR003886. Nidogen_extracell_dom. IPR000436. Sushi_SCR_CCP. [Graphical view]
Pfam	PF00008. EGF. 11 hits. PF00041. fn3. 3 hits. PF12661. hEGF. 2 hits. PF06119. NIDO. 1 hit. [Graphical view]
SMART	SM00032. CCP. 1 hit. SM00181. EGF. 10 hits. SM00179. EGF_CA. 5 hits. SM00060. FN3. 3 hits. SM00274. FOLN. 2 hits. SM00539. NIDO. 1 hit. [Graphical view]
SUPFAM	SSF57535. Complement_control_module. 1 hit. SSF49265. FN_III-like. 3 hits.
PROSITE	PS00010. ASX_HYDROXYL. 5 hits. PS00022. EGF_1. 15 hits. PS01186. EGF_2. 13 hits. PS50026. EGF_3. 15 hits. PS01187. EGF_CA. 3 hits. PS50853. FN3. 3 hits. PS51220. NIDO. 1 hit. PS50923. SUSHI. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35478263.

Entry information

Entry name

B5MEF5_HUMAN

Accession

Primary (citable) accession number: B5MEF5

Entry history

Integrated into UniProtKB/TrEMBL:	October 14, 2008
Last sequence update:	November 3, 2009
Last modified:	May 1, 2013
This is version 42 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.