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B5MEF5

- B5MEF5_HUMAN

UniProt

B5MEF5 - B5MEF5_HUMAN

Protein
Submitted name:

Sushi, nidogen and EGF-like domain-containing protein 1

Gene

SNED1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 2 (03 Nov 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro

    GO - Biological processi

    1. cell-matrix adhesion Source: InterPro

    Keywords - Ligandi

    CalciumSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Sushi, nidogen and EGF-like domain-containing protein 1Imported
    Gene namesi
    Name:SNED1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:24696. SNED1.

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Proteomic databases

    PRIDEiB5MEF5.

    Expressioni

    Gene expression databases

    ArrayExpressiB5MEF5.
    BgeeiB5MEF5.

    Structurei

    3D structure databases

    ProteinModelPortaliB5MEF5.
    SMRiB5MEF5. Positions 273-696, 753-1191.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    EGF-like domainUniRule annotationSAAS annotation, RepeatSAAS annotation, SushiSAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000081748.
    HOVERGENiHBG108495.

    Family and domain databases

    Gene3Di2.60.40.10. 3 hits.
    InterProiIPR000742. EG-like_dom.
    IPR001881. EGF-like_Ca-bd_dom.
    IPR013032. EGF-like_CS.
    IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
    IPR018097. EGF_Ca-bd_CS.
    IPR003961. Fibronectin_type3.
    IPR003645. Fol_N.
    IPR009030. Growth_fac_rcpt_N_dom.
    IPR013783. Ig-like_fold.
    IPR003886. Nidogen_extracell_dom.
    IPR000436. Sushi_SCR_CCP.
    [Graphical view]
    PfamiPF00008. EGF. 11 hits.
    PF00041. fn3. 3 hits.
    PF12661. hEGF. 2 hits.
    PF06119. NIDO. 1 hit.
    [Graphical view]
    SMARTiSM00032. CCP. 1 hit.
    SM00181. EGF. 10 hits.
    SM00179. EGF_CA. 5 hits.
    SM00060. FN3. 3 hits.
    SM00274. FOLN. 2 hits.
    SM00539. NIDO. 1 hit.
    [Graphical view]
    SUPFAMiSSF49265. SSF49265. 2 hits.
    SSF57184. SSF57184. 1 hit.
    SSF57535. SSF57535. 1 hit.
    PROSITEiPS00010. ASX_HYDROXYL. 5 hits.
    PS00022. EGF_1. 15 hits.
    PS01186. EGF_2. 13 hits.
    PS50026. EGF_3. 15 hits.
    PS01187. EGF_CA. 3 hits.
    PS50853. FN3. 3 hits.
    PS51220. NIDO. 1 hit.
    PS50923. SUSHI. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B5MEF5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRHGVAWALL VAAALGLGAR GVRGAVALAD FYPFGAERGD AVTPKQDDGG     50
    SGLRPLSVPF PFFGAEHSGL YVNNNGIISF LKEVSQFTPV AFPIAKDRCV 100
    VAAFWADVDN RRAGDVYYRE ATDPAMLRRA TEDVRHYFPE LLDFNATWVF 150
    VATWYRVTFF GGSSSSPVNT FQTVLITDGK LSFTIFNYES IVWTTGTHAS 200
    SGGNATGLGG IAAQAGFNAG DGQRYFSIPG SRTADMAEVE TTTNVGVPGR 250
    WAFRIDDAQV RVGGCGHTTS VCLALRPCLN GGKCIDDCVT GNPSYTCSCL 300
    SGFTGRRCHL DVNECASQPC QNGGTCTHGI NSFRCQCPAG FGGPTCETAQ 350
    SPCDTKECQH GGQCQVENGS AVCVCQAGYT GAACEMDVDD CSPDPCLNGG 400
    SCVDLVGNYT CLCAEPFKGL RCETGDHPVP DACLSAPCHN GGTCVDADQG 450
    YVCECPEGFM GLDCRERVPD DCECRNGGRC LGANTTLCQC PLGFFGLLCE 500
    FEITAMPCNM NTQCPDGGYC MEHGGSYLCV CHTDHNASHS LPSPCDSDPC 550
    FNGGSCDAHD DSYTCECPRG FHGKHCEKAR PHLCSSGPCR NGGTCKEAGG 600
    EYHCSCPYRF TGRHCEIGKP DSCASGPCHN GGTCFHYIGK YKCDCPPGFS 650
    GRHCEIAPSP CFRSPCVNGG TCEDRDTDFF CHCQAGYMGR RCQAEVDCGP 700
    PEEVKHATLR FNGTRLGAVA LYACDRGYSL SAPSRIRVCQ PHGVWSEPPQ 750
    CLEIDECRSQ PCLHGGSCQD RVAGYLCLCS TGYEGAHCEL ERDECRAHPC 800
    RNGGSCRNLP GAYVCRCPAG FVGVHCETEV DACDSSPCQH GGRCESGGGA 850
    YLCVCPESFF GYHCETVSDP CFSSPCGGRG YCLASNGSHS CTCKVGYTGE 900
    DCAKELFPPT ALKMERVEES GVSISWNPPN GPAARQMLDG YAVTYVSSDG 950
    SYRRTDFVDR TRSSHQLQAL AAGRAYNISV FSVKRNSNNK NDISRPAVLL 1000
    ARTRPRPVEG FEVTNVTAST ISVQWALHRI RHATVSGVRV SIRHPEALRD 1050
    QATDVDRSVD RFTFRALLPG KRYTIQLTTL SGLRGEEHPT ESLATAPTHV 1100
    WTRPLPPANL TAARVTATSA HVVWDAPTPG SLLEAYVINV TTSQSTKSRY 1150
    VPNGKLASYT VRDLLPGRRY QLSVIAVQST ELGPQHSEPA HLYIITSPRD 1200
    GADRRWHQGG HHPRVLKNRP PPARLPELRL LNDHSAPETP TQPPRFSELV 1250
    DGRGRVSARF GGSPSKAATV RSHVPGNCSE NPCQNGGTCV PGADAHSCDC 1300
    GPGFKGRRCE LACIKVSRPC TRLFSETKAF PVWEGGVCHH VYKRVYRVHQ 1350
    DICFKESCES TSLKKTPNRK QSKSQTLEKS 1380
    Length:1,380
    Mass (Da):148,699
    Last modified:November 3, 2009 - v2
    Checksum:i2F18B76D79C7D295
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC005237 Genomic DNA. No translation available.
    AC093585 Genomic DNA. No translation available.
    AC104809 Genomic DNA. No translation available.
    KF510803 Genomic DNA. No translation available.
    KF510805 Genomic DNA. No translation available.
    RefSeqiXP_006712469.1. XM_006712406.1.
    UniGeneiHs.471834.

    Genome annotation databases

    EnsembliENST00000342631; ENSP00000342992; ENSG00000162804.
    GeneIDi25992.
    KEGGihsa:25992.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC005237 Genomic DNA. No translation available.
    AC093585 Genomic DNA. No translation available.
    AC104809 Genomic DNA. No translation available.
    KF510803 Genomic DNA. No translation available.
    KF510805 Genomic DNA. No translation available.
    RefSeqi XP_006712469.1. XM_006712406.1.
    UniGenei Hs.471834.

    3D structure databases

    ProteinModelPortali B5MEF5.
    SMRi B5MEF5. Positions 273-696, 753-1191.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi B5MEF5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000342631 ; ENSP00000342992 ; ENSG00000162804 .
    GeneIDi 25992.
    KEGGi hsa:25992.

    Organism-specific databases

    CTDi 25992.
    HGNCi HGNC:24696. SNED1.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000081748.
    HOVERGENi HBG108495.

    Miscellaneous databases

    GenomeRNAii 25992.
    NextBioi 35478263.

    Gene expression databases

    ArrayExpressi B5MEF5.
    Bgeei B5MEF5.

    Family and domain databases

    Gene3Di 2.60.40.10. 3 hits.
    InterProi IPR000742. EG-like_dom.
    IPR001881. EGF-like_Ca-bd_dom.
    IPR013032. EGF-like_CS.
    IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
    IPR018097. EGF_Ca-bd_CS.
    IPR003961. Fibronectin_type3.
    IPR003645. Fol_N.
    IPR009030. Growth_fac_rcpt_N_dom.
    IPR013783. Ig-like_fold.
    IPR003886. Nidogen_extracell_dom.
    IPR000436. Sushi_SCR_CCP.
    [Graphical view ]
    Pfami PF00008. EGF. 11 hits.
    PF00041. fn3. 3 hits.
    PF12661. hEGF. 2 hits.
    PF06119. NIDO. 1 hit.
    [Graphical view ]
    SMARTi SM00032. CCP. 1 hit.
    SM00181. EGF. 10 hits.
    SM00179. EGF_CA. 5 hits.
    SM00060. FN3. 3 hits.
    SM00274. FOLN. 2 hits.
    SM00539. NIDO. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49265. SSF49265. 2 hits.
    SSF57184. SSF57184. 1 hit.
    SSF57535. SSF57535. 1 hit.
    PROSITEi PS00010. ASX_HYDROXYL. 5 hits.
    PS00022. EGF_1. 15 hits.
    PS01186. EGF_2. 13 hits.
    PS50026. EGF_3. 15 hits.
    PS01187. EGF_CA. 3 hits.
    PS50853. FN3. 3 hits.
    PS51220. NIDO. 1 hit.
    PS50923. SUSHI. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiB5MEF5_HUMAN
    AccessioniPrimary (citable) accession number: B5MEF5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 14, 2008
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 54 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3