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Protein
Submitted name:

Pyrroline-5-carboxylate reductase 3

Gene

PYCR3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Pyrroline-5-carboxylate reductase 3Imported
Gene namesi
Name:PYCR3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

HGNCiHGNC:25846. PYCR3.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000104524.

Expressioni

Gene expression databases

BgeeiENSG00000104524.

Interactioni

Protein-protein interaction databases

IntActiB5MD87. 2 interactors.
STRINGi9606.ENSP00000220966.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 134P5CR_dimerInterPro annotationAdd BLAST105

Phylogenomic databases

eggNOGiKOG3124. Eukaryota.
COG0345. LUCA.
GeneTreeiENSGT00390000007443.
HOGENOMiHOG000230247.
HOVERGENiHBG053399.

Family and domain databases

InterProiView protein in InterPro
IPR008927. 6-PGluconate_DH_C-like.
IPR029036. P5CR_dimer.
IPR000304. Pyrroline-COOH_reductase.
PANTHERiPTHR11645. PTHR11645. 1 hit.
PfamiView protein in Pfam
PF14748. P5CR_dimer. 1 hit.
SUPFAMiSSF48179. SSF48179. 1 hit.
PROSITEiView protein in PROSITE
PS00521. P5CR. 1 hit.

Sequencei

Sequence statusi: Complete.

B5MD87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARGRHVGSS ETKLLQHLLE ACGRCEEVPE AYVDIHTGLS GSGVAFVCAF
60 70 80 90 100
SEALAEGAVK MGMPSSLAHR IAAQTLLGTA KMLLHEGQHP AQLRSDVCTP
110 120 130
GGTTIYGLHA LEQGGLRAAT MSAVEAATCR AKELSRK
Length:137
Mass (Da):14,341
Last modified:June 28, 2011 - v2
Checksum:i39A022047966FB6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC067930 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000377579; ENSP00000366802; ENSG00000104524.
ENST00000634183; ENSP00000487676; ENSG00000276657.
UCSCiuc064rcj.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC067930 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiB5MD87. 2 interactors.
STRINGi9606.ENSP00000220966.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000377579; ENSP00000366802; ENSG00000104524.
ENST00000634183; ENSP00000487676; ENSG00000276657.
UCSCiuc064rcj.1. human.

Organism-specific databases

HGNCiHGNC:25846. PYCR3.
OpenTargetsiENSG00000104524.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3124. Eukaryota.
COG0345. LUCA.
GeneTreeiENSGT00390000007443.
HOGENOMiHOG000230247.
HOVERGENiHBG053399.

Gene expression databases

BgeeiENSG00000104524.

Family and domain databases

InterProiView protein in InterPro
IPR008927. 6-PGluconate_DH_C-like.
IPR029036. P5CR_dimer.
IPR000304. Pyrroline-COOH_reductase.
PANTHERiPTHR11645. PTHR11645. 1 hit.
PfamiView protein in Pfam
PF14748. P5CR_dimer. 1 hit.
SUPFAMiSSF48179. SSF48179. 1 hit.
PROSITEiView protein in PROSITE
PS00521. P5CR. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB5MD87_HUMAN
AccessioniPrimary (citable) accession number: B5MD87
Entry historyiIntegrated into UniProtKB/TrEMBL: October 14, 2008
Last sequence update: June 28, 2011
Last modified: June 7, 2017
This is version 67 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.