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Protein
Submitted name:

Bromodomain-containing protein 8

Gene

BRD8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Bromodomain-containing protein 8Imported
Gene namesi
Name:BRD8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

HGNCiHGNC:19874. BRD8.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000112983.

PTM / Processingi

Proteomic databases

EPDiB5MCW3.
MaxQBiB5MCW3.
PaxDbiB5MCW3.
PeptideAtlasiB5MCW3.
PRIDEiB5MCW3.

Expressioni

Gene expression databases

BgeeiENSG00000112983.
ExpressionAtlasiB5MCW3. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000254900.

Structurei

3D structure databases

ProteinModelPortaliB5MCW3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini724 – 794BromoInterPro annotationAdd BLAST71

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili98 – 132Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IF07. Eukaryota.
ENOG410Y97J. LUCA.
GeneTreeiENSGT00530000064262.
HOGENOMiHOG000074125.
HOVERGENiHBG050732.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
InterProiIPR001487. Bromodomain.
[Graphical view]
PfamiPF00439. Bromodomain. 1 hit.
[Graphical view]
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 1 hit.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 1 hit.
PROSITEiPS50014. BROMODOMAIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5MCW3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATGTGKHKL LSTGPTEPWS IREKLCLASS VMRSGDQNWV SVSRAIKPFA
60 70 80 90 100
EPGRPPDWFS QKHCASQYSE LLETTETPKR KRGEKGEVVE TVEDVIVRKL
110 120 130 140 150
TAERVEELKK VIKETQERYR RLKRDAELIQ AGHMDSRLDE LCNDIATKKK
160 170 180 190 200
LEEEEAEVKR KATDAAYQAR QAVKTPPRRL PTVMVRSPID SASPGGDYPL
210 220 230 240 250
GDLTPTTMEE ATSGVNESEM AVASGHLNST GVLLEVGGVL PMIHGGEIQQ
260 270 280 290 300
TPNTVAASPA ASGAPTLSRL LEAGPTQFTT PLASFTTVAS EPPVKLVPPP
310 320 330 340 350
VESVSQATIV MMPALPAPSS APAVSTTESV APVSQPDNCV PMEAVGDPHT
360 370 380 390 400
VTVSMDSSEI SMIINSIKEE CFRSGVAEAP VGSKAPSIDG KEELDLAEKM
410 420 430 440 450
DIAVSYTGEE LDFETVGDII AIIEDKVDDH PEVLDVAAVE AALSFCEEND
460 470 480 490 500
DPQSLPGPWE HPIQQERDKP VPLPAPEMTV KQERLDFEET ENKGIHELVD
510 520 530 540 550
IREPSAEIKV EPAEPEPVIS GAEIVAGVVP ATSMEPPELR SQDLDEELGS
560 570 580 590 600
TAAGEIVEAD VAIGKGDETP LTNVKTEASP ESMLSPSHGS NPIEDPLEAE
610 620 630 640 650
TQHKFEMSDS LKEESGTIFG SQIKDAPGED EEEDGVSEAA SLEEPKEEDQ
660 670 680 690 700
GEGYLSEMDN EPPVSESDDG FSIHNATLQS HTLADSIPSS PASSQFSVCS
710 720 730 740 750
EDQEAIQAQK IWKKAIMLVW RAAANHRYAN VFLQPVTDDI APGYHSIVQR
760 770 780 790 800
PMDLSTIKKN IENGLIRSTA EFQRDIMLMF QNAVMYNSSD HDVYHMAVEM
810 820 830 840 850
QRDVLEQIQQ FLATQLIMQT SESGISAKSL RGRDSTRKQD ASEKDSVPMG
860 870
SPAFLLSLFD GGTRGRRCAI EADMKMKK
Length:878
Mass (Da):95,362
Last modified:October 14, 2008 - v1
Checksum:iB032EA0F741656F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC106752 Genomic DNA. No translation available.
AC109442 Genomic DNA. No translation available.
AC113382 Genomic DNA. No translation available.
RefSeqiXP_005271918.1. XM_005271861.3.
UniGeneiHs.519337.

Genome annotation databases

EnsembliENST00000402931; ENSP00000384845; ENSG00000112983.
GeneIDi10902.
UCSCiuc063hjf.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC106752 Genomic DNA. No translation available.
AC109442 Genomic DNA. No translation available.
AC113382 Genomic DNA. No translation available.
RefSeqiXP_005271918.1. XM_005271861.3.
UniGeneiHs.519337.

3D structure databases

ProteinModelPortaliB5MCW3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000254900.

Proteomic databases

EPDiB5MCW3.
MaxQBiB5MCW3.
PaxDbiB5MCW3.
PeptideAtlasiB5MCW3.
PRIDEiB5MCW3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000402931; ENSP00000384845; ENSG00000112983.
GeneIDi10902.
UCSCiuc063hjf.1. human.

Organism-specific databases

CTDi10902.
HGNCiHGNC:19874. BRD8.
OpenTargetsiENSG00000112983.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IF07. Eukaryota.
ENOG410Y97J. LUCA.
GeneTreeiENSGT00530000064262.
HOGENOMiHOG000074125.
HOVERGENiHBG050732.

Miscellaneous databases

ChiTaRSiBRD8. human.
GenomeRNAii10902.

Gene expression databases

BgeeiENSG00000112983.
ExpressionAtlasiB5MCW3. baseline and differential.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
InterProiIPR001487. Bromodomain.
[Graphical view]
PfamiPF00439. Bromodomain. 1 hit.
[Graphical view]
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 1 hit.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 1 hit.
PROSITEiPS50014. BROMODOMAIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB5MCW3_HUMAN
AccessioniPrimary (citable) accession number: B5MCW3
Entry historyi
Integrated into UniProtKB/TrEMBL: October 14, 2008
Last sequence update: October 14, 2008
Last modified: November 30, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.