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Protein

UDP-glucuronosyltransferase

Gene

UGT1A6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucuronosyltransferaseUniRule annotation (EC:2.4.1.17UniRule annotation)
Gene namesi
Name:UGT1A6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000167165.18.
HGNCiHGNC:12538. UGT1A6.

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000167165.

PTM / Processingi

Proteomic databases

MaxQBiB5MCT4.

Expressioni

Gene expression databases

BgeeiENSG00000167165.
ExpressionAtlasiB5MCT4. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini86 – 129UDPGTInterPro annotationAdd BLAST44

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili145 – 172Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1192. Eukaryota.
COG1819. LUCA.
GeneTreeiENSGT00760000118949.
HOVERGENiHBG104751.

Family and domain databases

InterProiView protein in InterPro
IPR002213. UDP_glucos_trans.
IPR035595. UDP_glycos_trans_CS.
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiView protein in Pfam
PF00201. UDPGT. 1 hit.
PROSITEiView protein in PROSITE
PS00375. UDPGT. 1 hit.

Sequencei

Sequence statusi: Complete.

B5MCT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPNMVFIGGI NCKKRKDLSQ EFEAYINASG EHGIVVFSLG SMVSEIPEKK
60 70 80 90 100
AMAIADALGK IPQTVLWRYT GTRPSNLANN TILVKWLPQN DLLGHPMTRA
110 120 130 140 150
FITHAGSHGV YESICNGVPM VMMPLFGDQM DNAKRMETKG AGVTLNVLEM
160 170
TSEDLENALK AVINDKRKKQ QSGRQM
Length:176
Mass (Da):19,424
Last modified:October 14, 2008 - v1
Checksum:iAB6A151DE978D7D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006985 Genomic DNA. No translation available.
AC114812 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000406651; ENSP00000386107; ENSG00000167165.
ENST00000446481; ENSP00000401541; ENSG00000167165.
UCSCiuc061tvn.1. human.

Similar proteinsi

Entry informationi

Entry nameiB5MCT4_HUMAN
AccessioniPrimary (citable) accession number: B5MCT4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 14, 2008
Last sequence update: October 14, 2008
Last modified: October 25, 2017
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported