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B5MCN3

- S14L6_HUMAN

UniProt

B5MCN3 - S14L6_HUMAN

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Protein

Putative SEC14-like protein 6

Gene
SEC14L6
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Protein uncertaini

Functioni

GO - Molecular functioni

  1. transporter activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Putative SEC14-like protein 6
Gene namesi
Name:SEC14L6
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 22

Organism-specific databases

HGNCiHGNC:40047. SEC14L6.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
  2. intracellular Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 397397Putative SEC14-like protein 6PRO_0000410725Add
BLAST

Proteomic databases

PaxDbiB5MCN3.
PRIDEiB5MCN3.

Expressioni

Gene expression databases

BgeeiB5MCN3.

Structurei

3D structure databases

ProteinModelPortaliB5MCN3.
SMRiB5MCN3. Positions 1-397.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini76 – 249174CRAL-TRIOAdd
BLAST
Domaini252 – 383132GOLDAdd
BLAST

Sequence similaritiesi

Contains 1 CRAL-TRIO domain.
Contains 1 GOLD domain.

Phylogenomic databases

eggNOGiNOG309458.
HOGENOMiHOG000232201.
HOVERGENiHBG055336.
OMAiANILAWQ.
OrthoDBiEOG7N8ZVD.
PhylomeDBiB5MCN3.
TreeFamiTF313988.

Family and domain databases

Gene3Di3.40.525.10. 1 hit.
InterProiIPR001071. CRAL-bd_toc_tran.
IPR001251. CRAL-TRIO_dom.
IPR011074. CRAL/TRIO_N_dom.
IPR009038. GOLD.
[Graphical view]
PfamiPF00650. CRAL_TRIO. 1 hit.
PF03765. CRAL_TRIO_N. 1 hit.
[Graphical view]
PRINTSiPR00180. CRETINALDHBP.
SMARTiSM01100. CRAL_TRIO_N. 1 hit.
SM00516. SEC14. 1 hit.
[Graphical view]
SUPFAMiSSF101576. SSF101576. 1 hit.
SSF46938. SSF46938. 1 hit.
SSF52087. SSF52087. 1 hit.
PROSITEiPS50191. CRAL_TRIO. 1 hit.
PS50866. GOLD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5MCN3-1 [UniParc]FASTAAdd to Basket

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MSGQVGDLSP SQEKSLAQFR ENIQDVLSAL PNPDDYFLLR WLQARSFDLQ    50
KSEDMLRKHM EFRKQQDLAN ILAWQPPEVV RLYNANGICG HDGEGSPVWY 100
HIVGSLDPKG LLLSASKQEL LRDSFRSCEL LLRECELQSQ KLGKRVEKII 150
AIFGLEGLGL RDLWKPGIEL LQEFFSALEA NYPEILKSLI VVRAPKLFAV 200
AFNLVKSYMS EETRRKVVIL GDNWKQELTK FISPDQLPVE FGGTMTDPDG 250
NPKCLTKINY GGEVPKSYYL CKQVRLQYEH TRSVGRGSSL QVENEILFPG 300
CVLRWQFASD GGDIGFGVFL KTKMGERQRA REMTEVLPSQ RYNAHMVPED 350
GILTCLQAGS YVLRFYNTYS LVHSKRISYT VEVLLPDQTF MEKMEKF 397
Length:397
Mass (Da):45,364
Last modified:October 14, 2008 - v1
Checksum:iBB45CFE2EA9CBB81
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC004832 Genomic DNA. No translation available.
CCDSiCCDS54518.1.
RefSeqiNP_001180265.2. NM_001193336.2.
UniGeneiHs.505605.

Genome annotation databases

EnsembliENST00000402034; ENSP00000385695; ENSG00000214491.
GeneIDi730005.
KEGGihsa:730005.
UCSCiuc021wnu.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC004832 Genomic DNA. No translation available.
CCDSi CCDS54518.1.
RefSeqi NP_001180265.2. NM_001193336.2.
UniGenei Hs.505605.

3D structure databases

ProteinModelPortali B5MCN3.
SMRi B5MCN3. Positions 1-397.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi B5MCN3.
PRIDEi B5MCN3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000402034 ; ENSP00000385695 ; ENSG00000214491 .
GeneIDi 730005.
KEGGi hsa:730005.
UCSCi uc021wnu.1. human.

Organism-specific databases

CTDi 730005.
GeneCardsi GC22M030921.
HGNCi HGNC:40047. SEC14L6.
neXtProti NX_B5MCN3.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG309458.
HOGENOMi HOG000232201.
HOVERGENi HBG055336.
OMAi ANILAWQ.
OrthoDBi EOG7N8ZVD.
PhylomeDBi B5MCN3.
TreeFami TF313988.

Miscellaneous databases

ChiTaRSi SEC14L6. human.
GenomeRNAii 730005.
NextBioi 132011.

Gene expression databases

Bgeei B5MCN3.

Family and domain databases

Gene3Di 3.40.525.10. 1 hit.
InterProi IPR001071. CRAL-bd_toc_tran.
IPR001251. CRAL-TRIO_dom.
IPR011074. CRAL/TRIO_N_dom.
IPR009038. GOLD.
[Graphical view ]
Pfami PF00650. CRAL_TRIO. 1 hit.
PF03765. CRAL_TRIO_N. 1 hit.
[Graphical view ]
PRINTSi PR00180. CRETINALDHBP.
SMARTi SM01100. CRAL_TRIO_N. 1 hit.
SM00516. SEC14. 1 hit.
[Graphical view ]
SUPFAMi SSF101576. SSF101576. 1 hit.
SSF46938. SSF46938. 1 hit.
SSF52087. SSF52087. 1 hit.
PROSITEi PS50191. CRAL_TRIO. 1 hit.
PS50866. GOLD. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The DNA sequence of human chromosome 22."
    Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M.
    , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H.
    Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiS14L6_HUMAN
AccessioniPrimary (citable) accession number: B5MCN3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 28, 2011
Last sequence update: October 14, 2008
Last modified: July 9, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Product of a dubious gene prediction.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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