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Protein
Submitted name:

Prolactin regulatory element-binding protein

Gene

PREB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

SignaLinkiB5MC98.

Names & Taxonomyi

Protein namesi
Submitted name:
Prolactin regulatory element-binding proteinImported
Gene namesi
Name:PREBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000138073.13.
HGNCiHGNC:9356. PREB.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei256 – 280HelicalSequence analysisAdd BLAST25
Transmembranei333 – 355HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000138073.

PTM / Processingi

Proteomic databases

MaxQBiB5MC98.
PeptideAtlasiB5MC98.
PRIDEiB5MC98.

Expressioni

Gene expression databases

BgeeiENSG00000138073.
ExpressionAtlasiB5MC98. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliB5MC98.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini160 – 232WD_REPEATS_REGIONInterPro annotationAdd BLAST73
Repeati160 – 191WDPROSITE-ProRule annotationAdd BLAST32

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis, WD repeatPROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000018031.
HOGENOMiHOG000045302.
HOVERGENiHBG002027.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiView protein in InterPro
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
PfamiView protein in Pfam
PF00400. WD40. 1 hit.
SMARTiView protein in SMART
SM00320. WD40. 3 hits.
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiView protein in PROSITE
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

B5MC98-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRRRAPELY RAPFPLYALQ VDPSTGLLIA AGGGGAAKTG IKNGVHFLQL
60 70 80 90 100
ELINGRLSAS LLHSHDTETR ATMNLALAGD ILAAGQDAHC QLLRFQAHQQ
110 120 130 140 150
QGNKAEKAGS KEQGPRQRKG AAPAEKKCGA ETQHEGLELR VENLQAVQTD
160 170 180 190 200
FSSDPLQKVV CFNHDNTLLA TGGTDGYVRV WKVPSLEKVL EFKAHEGEIE
210 220 230 240 250
DLALGPDGKL VTVGRDLKAS VWQKDQLVTQ LHWQENGPTF SSTPYRYQAC
260 270 280 290 300
SESGTFLGLG TVTGSVAIYI AFSLQCLYYV REAHGIVVTD VAFLPEKGRG
310 320 330 340 350
PELLGSHETA LFSVAVDSRC QLHLLPSRRS VPVWLLLLLC VGLIIVTILL

LQSAFPGFL
Length:359
Mass (Da):38,940
Last modified:October 14, 2008 - v1
Checksum:iF34D9518422A1218
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013403 Genomic DNA. No translation available.
RefSeqiNP_001317414.1. NM_001330485.1.
UniGeneiHs.279784.

Genome annotation databases

EnsembliENST00000406567; ENSP00000384032; ENSG00000138073.
GeneIDi10113.
UCSCiuc061hkq.1. human.

Similar proteinsi

Entry informationi

Entry nameiB5MC98_HUMAN
AccessioniPrimary (citable) accession number: B5MC98
Entry historyiIntegrated into UniProtKB/TrEMBL: October 14, 2008
Last sequence update: October 14, 2008
Last modified: September 27, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported