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B5IH56

- B5IH56_ACIB4

UniProt

B5IH56 - B5IH56_ACIB4

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Protein

Ribulose bisphosphate carboxylase

Gene
rbcL, Aboo_1084, ABOONEI_952
Organism
Aciduliprofundum boonei (strain DSM 19572 / T469)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the addition of molecular CO2 and H2O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase By similarity.UniRule annotation

Catalytic activityi

2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

Cofactori

Binds 1 magnesium ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei149 – 1491Proton acceptor By similarityUniRule annotation
Binding sitei151 – 1511Substrate By similarityUniRule annotation
Metal bindingi175 – 1751Magnesium; via carbamate group By similarityUniRule annotation
Metal bindingi177 – 1771Magnesium By similarityUniRule annotation
Metal bindingi178 – 1781Magnesium By similarityUniRule annotation
Active sitei265 – 2651Proton acceptor By similarityUniRule annotation
Binding sitei266 – 2661Substrate By similarityUniRule annotation
Binding sitei298 – 2981Substrate By similarityUniRule annotation
Sitei305 – 3051Transition state stabilizer By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: InterPro
  2. ribulose-bisphosphate carboxylase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbon fixation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported, OxidoreductaseUniRule annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciABOO439481:GJNL-1119-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribulose bisphosphate carboxylaseUniRule annotation (EC:4.1.1.39UniRule annotation)
Short name:
RuBisCOUniRule annotation
Gene namesi
Name:rbcLUniRule annotation
Ordered Locus Names:Aboo_1084Imported
ORF Names:ABOONEI_952Imported
OrganismiAciduliprofundum boonei (strain DSM 19572 / T469)
Taxonomic identifieri439481 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaAciduliprofundum
ProteomesiUP000001400: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei175 – 1751N6-carboxylysine By similarityUniRule annotation

Interactioni

Subunit structurei

Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB5IH56.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni347 – 3493Substrate binding By similarityUniRule annotation
Regioni369 – 3724Substrate binding By similarityUniRule annotation

Sequence similaritiesi

Belongs to the RuBisCO large chain family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000230831.
KOiK01601.
OMAiFTQDWAS.

Family and domain databases

Gene3Di3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
InterProiIPR017712. RuBisCO_III.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view]
PfamiPF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view]
SUPFAMiSSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
TIGRFAMsiTIGR03326. rubisco_III. 1 hit.

Sequencei

Sequence statusi: Complete.

B5IH56-1 [UniParc]FASTAAdd to Basket

« Hide

MTYIDLNYQP RESDLLVWFR AEPPAGKDMK YVADRIAEES SIGTWTDLKT    50
LLPEIWEKLR ARVYEIDEKN KYVKIAYPLH LFEIKNMPAI LASVAGNVFG 100
MKSVEALRVL DIRFPKELIQ GYLGPKYGVQ GVREMTKVYD RPFLGTIIKP 150
KIGLPAKMHA EVAYEAWVGG LDIVKDDENL ASQEFNRFEE RLALTLEKKD 200
IAEEETGEKK IYLVNITAPY KEMIRRAELV QDSGNEFVMI DVFISGFSAV 250
QSYREEGFKM AIHAHRAMHA AITRNPEHGI NMLTLAKVYR LLGVDNLHIG 300
TAVGKMEGSA KEVSEIREEI QLENVPANES RFEQKWYEIK PVLAVASGGL 350
HPGHVPAVVD ILGKDIVIQA GGGVHGHPEG TRAGAKAMRE ALEAKMQGIP 400
LEEYAKEHKE LREALEKFLH 420
Length:420
Mass (Da):47,364
Last modified:October 14, 2008 - v1
Checksum:iC8667540053F3B77
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001941 Genomic DNA. Translation: ADD08893.1.
DS990535 Genomic DNA. Translation: EDY34409.1.
RefSeqiWP_008086508.1. NZ_DS990535.1.
YP_003483455.1. NC_013926.1.

Genome annotation databases

EnsemblBacteriaiADD08893; ADD08893; Aboo_1084.
EDY34409; EDY34409; ABOONEI_952.
GeneIDi8828042.
KEGGiabi:Aboo_1084.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001941 Genomic DNA. Translation: ADD08893.1 .
DS990535 Genomic DNA. Translation: EDY34409.1 .
RefSeqi WP_008086508.1. NZ_DS990535.1.
YP_003483455.1. NC_013926.1.

3D structure databases

ProteinModelPortali B5IH56.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADD08893 ; ADD08893 ; Aboo_1084 .
EDY34409 ; EDY34409 ; ABOONEI_952 .
GeneIDi 8828042.
KEGGi abi:Aboo_1084.

Phylogenomic databases

HOGENOMi HOG000230831.
KOi K01601.
OMAi FTQDWAS.

Enzyme and pathway databases

BioCyci ABOO439481:GJNL-1119-MONOMER.

Family and domain databases

Gene3Di 3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
InterProi IPR017712. RuBisCO_III.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view ]
Pfami PF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view ]
SUPFAMi SSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
TIGRFAMsi TIGR03326. rubisco_III. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Electron microscopy encounters with unusual thermophiles helps direct genomic analysis of Aciduliprofundum boonei."
    Reysenbach A.L., Flores G.E.
    Geobiology 6:331-336(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: T469Imported.
  2. "Complete sequence of Aciduliprofundum boonei T469."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Saunders E., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Mikhailova N., Flores G., Reysenbach A.-L., Woyke T.
    Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: T469Imported.
  3. "Complete sequence of Aciduliprofundum boonei T469."
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Saunders E., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Mikhailova N., Flores G., Reysenbach A.-L., Woyke T.
    Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 19572 / T469.

Entry informationi

Entry nameiB5IH56_ACIB4
AccessioniPrimary (citable) accession number: B5IH56
Entry historyi
Integrated into UniProtKB/TrEMBL: October 14, 2008
Last sequence update: October 14, 2008
Last modified: September 3, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O2 to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains By similarity.UniRule annotation

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi