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B5I9H4 (RIBL_ACIB4) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
FAD synthase

EC=2.7.7.2
Alternative name(s):
FMN adenylyltransferase
Flavin adenine dinucleotide synthase
Gene names
Name:ribL
Ordered Locus Names:Aboo_0747
ORF Names:ABOONEI_1934, ABOONEI_2228
OrganismAciduliprofundum boonei (strain DSM 19572 / T469) [Complete proteome] [HAMAP]
Taxonomic identifier439481 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaAciduliprofundum

Protein attributes

Sequence length149 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme By similarity. HAMAP-Rule MF_02115

Catalytic activity

ATP + FMN = diphosphate + FAD. HAMAP-Rule MF_02115

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_02115

Pathway

Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1. HAMAP-Rule MF_02115

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_02115

Sequence similarities

Belongs to the archaeal FAD synthase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 149149FAD synthase HAMAP-Rule MF_02115
PRO_0000406231

Regions

Nucleotide binding9 – 102ATP By similarity
Nucleotide binding14 – 174ATP By similarity
Nucleotide binding91 – 944ATP By similarity

Sites

Binding site1201ATP; via amide nitrogen By similarity

Experimental info

Sequence conflict251R → K in EDY36241. Ref.1
Sequence conflict531D → E in EDY36241. Ref.1

Sequences

Sequence LengthMass (Da)Tools
B5I9H4 [UniParc].

Last modified October 14, 2008. Version 1.
Checksum: F820A8DD1EC44056

FASTA14917,380
        10         20         30         40         50         60 
MVRVMATGVF DILHPGHVLF LREARKLGDE LVVVVARDST VERLKHKPIM NEDIRRFMVE 

        70         80         90        100        110        120 
SLKPVDRAVL GHKDDMYKTV EDVRPDIIVL GYDQKFDEKE IEEECRKRGI KVKVVRLKKY 

       130        140 
GDSDLNGTRK IIFKIVDRVD DLYAKDRNS 

« Hide

References

[1]"Electron microscopy encounters with unusual thermophiles helps direct genomic analysis of Aciduliprofundum boonei."
Reysenbach A.L., Flores G.E.
Geobiology 6:331-336(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 19572 / T469.
[2]"Complete sequence of Aciduliprofundum boonei T469."
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Saunders E., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Mikhailova N., Flores G., Reysenbach A.-L., Woyke T.
Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 19572 / T469.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS990515 Genomic DNA. Translation: EDY37013.1.
DS990517 Genomic DNA. Translation: EDY36241.1.
CP001941 Genomic DNA. Translation: ADD08556.1.
RefSeqYP_003483118.1. NC_013926.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADD08556; ADD08556; Aboo_0747.
EDY36241; EDY36241; ABOONEI_2228.
EDY37013; EDY37013; ABOONEI_1934.
GeneID8827694.
KEGGabi:Aboo_0747.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000284153.
KOK14656.
OMAIVLGHDQ.

Enzyme and pathway databases

BioCycABOO439481:GJNL-767-MONOMER.
UniPathwayUPA00277; UER00407.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_02115. FAD_synth_arch.
InterProIPR004821. Cyt_trans-like.
IPR024902. FAD_synth_RibL.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR00125. cyt_tran_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRIBL_ACIB4
AccessionPrimary (citable) accession number: B5I9H4
Secondary accession number(s): B5IC32
Entry history
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: October 14, 2008
Last modified: May 14, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways