ID   B5FYR4_TAEGU            Unreviewed;       147 AA.
AC   B5FYR4;
DT   14-OCT-2008, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2008, sequence version 1.
DT   27-MAR-2024, entry version 89.
DE   SubName: Full=Microsomal glutathione S-transferase 3 {ECO:0000313|EMBL:ACH44175.1, ECO:0000313|Ensembl:ENSTGUP00000017602.1};
GN   Name=MGST3 {ECO:0000313|Ensembl:ENSTGUP00000017602.1};
OS   Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC   Estrildinae; Taeniopygia.
OX   NCBI_TaxID=59729 {ECO:0000313|EMBL:ACH44175.1};
RN   [1] {ECO:0000313|EMBL:ACH44175.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Whole brain {ECO:0000313|EMBL:ACH44175.1};
RX   PubMed=17018643; DOI=10.1073/pnas.0607098103;
RA   Wada K., Howard J.T., McConnell P., Whitney O., Lints T., Rivas M.V.,
RA   Horita H., Patterson M.A., White S.A., Scharff C., Haesler S., Zhao S.,
RA   Sakaguchi H., Hagiwara M., Shiraki T., Hirozane-Kishikawa T., Skene P.,
RA   Hayashizaki Y., Carninci P., Jarvis E.D.;
RT   "A molecular neuroethological approach for identifying and characterizing a
RT   cascade of behaviorally regulated genes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15212-15217(2006).
RN   [2] {ECO:0000313|Ensembl:ENSTGUP00000017602.1, ECO:0000313|Proteomes:UP000007754}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20360741; DOI=10.1038/nature08819;
RA   Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA   Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA   Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA   Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA   Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA   Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA   Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA   McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA   Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA   Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA   Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA   Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA   Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA   Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT   "The genome of a songbird.";
RL   Nature 464:757-762(2010).
RN   [3] {ECO:0000313|Ensembl:ENSTGUP00000017602.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; DQ214111; ACH44175.1; -; mRNA.
DR   EMBL; DQ214112; ACH44176.1; -; mRNA.
DR   RefSeq; NP_001232611.1; NM_001245682.1.
DR   STRING; 59729.ENSTGUP00000017602; -.
DR   Ensembl; ENSTGUT00000018004.2; ENSTGUP00000017602.1; ENSTGUG00000017321.2.
DR   GeneID; 100190664; -.
DR   KEGG; tgu:100190664; -.
DR   CTD; 4259; -.
DR   GeneTree; ENSGT00390000008608; -.
DR   HOGENOM; CLU_110291_1_0_1; -.
DR   OMA; ACQHLGW; -.
DR   OrthoDB; 5487436at2759; -.
DR   TreeFam; TF105328; -.
DR   Proteomes; UP000007754; Chromosome 8.
DR   GO; GO:0005741; C:mitochondrial outer membrane; IEA:Ensembl.
DR   GO; GO:0004602; F:glutathione peroxidase activity; IEA:Ensembl.
DR   GO; GO:0004364; F:glutathione transferase activity; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0004464; F:leukotriene-C4 synthase activity; IEA:Ensembl.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006692; P:prostanoid metabolic process; IEA:Ensembl.
DR   Gene3D; 1.20.120.550; Membrane associated eicosanoid/glutathione metabolism-like domain; 1.
DR   InterPro; IPR023352; MAPEG-like_dom_sf.
DR   InterPro; IPR001129; Membr-assoc_MAPEG.
DR   PANTHER; PTHR10250; MICROSOMAL GLUTATHIONE S-TRANSFERASE; 1.
DR   PANTHER; PTHR10250:SF27; MICROSOMAL GLUTATHIONE S-TRANSFERASE 3; 1.
DR   Pfam; PF01124; MAPEG; 1.
DR   SUPFAM; SSF161084; MAPEG domain-like; 1.
PE   2: Evidence at transcript level;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW   Transferase {ECO:0000313|EMBL:ACH44175.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        117..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   147 AA;  16158 MW;  1B258E4C29BA5503 CRC64;
     MAVLSKEYGY VMLTGAASFV LVMHLAINVG KARKKYRVEY PAMYSTDPEH GQIFNCIQRA
     HQNTLEVYPA FLFFLGTGGL HHPRVATGLG IAWIVGRLLY AYGYYTGDPK NRRRGALGSV
     ALLGLVGTGI YSACQHLGWV SQQGCRS
//