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Protein

Uronate isomerase

Gene

uxaC

Organism
Salmonella dublin (strain CT_02021853)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciSENT439851:GH2Z-3442-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:SeD_A3482
OrganismiSalmonella dublin (strain CT_02021853)
Taxonomic identifieri439851 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 470470Uronate isomerasePRO_1000131601Add
BLAST

Proteomic databases

PRIDEiB5FV01.

Structurei

3D structure databases

ProteinModelPortaliB5FV01.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiEOG6J1D95.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

B5FV01-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATFMTEDFL LKNDIARTLY HKYAAPMPIY DFHCHLSPQE IADDRRFDNL
60 70 80 90 100
GQIWLEGDHY KWRALRSAGV DESLITGKET SDYEKYMAWA NTVPKTLGNP
110 120 130 140 150
LYHWTHLELR RPFGITGTLF GPDTAESIWT QCNEKLATPA FSARGIMQQM
160 170 180 190 200
NVRMVGTTDD PIDSLEYHRQ IAADDSIDIE VAPSWRPDKV FKIELDGFVD
210 220 230 240 250
YLRKLEAAAD VSITRFDDLR QALTRRLDHF AACGCRASDH GIETLRFAPV
260 270 280 290 300
PDDAQLDAIL GKRLAGETLS ELEIAQFTTA VLVWLGRQYA ARGWVMQLHI
310 320 330 340 350
GAIRNNNTRM FRLLGPDTGF DSIGDNNISW ALSRLLDSMD VTNELPKTIL
360 370 380 390 400
YCLNPRDNEV LATMIGNFQG PGIAGKVQFG SGWWFNDQKD GMLRQLEQLS
410 420 430 440 450
QMGLLSQFVG MLTDSRSFLS YTRHEYFRRI LCNLLGQWAQ DGEIPDDEAM
460 470
LSRMVQDICF NNAQRYFTIK
Length:470
Mass (Da):53,610
Last modified:October 14, 2008 - v1
Checksum:i78D5EE0CB2B11218
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001144 Genomic DNA. Translation: ACH75486.1.
RefSeqiWP_000190182.1. NC_011205.1.

Genome annotation databases

EnsemblBacteriaiACH75486; ACH75486; SeD_A3482.
KEGGised:SeD_A3482.
PATRICi18495053. VBISalEnt111443_3441.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001144 Genomic DNA. Translation: ACH75486.1.
RefSeqiWP_000190182.1. NC_011205.1.

3D structure databases

ProteinModelPortaliB5FV01.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB5FV01.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACH75486; ACH75486; SeD_A3482.
KEGGised:SeD_A3482.
PATRICi18495053. VBISalEnt111443_3441.

Phylogenomic databases

HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiEOG6J1D95.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciSENT439851:GH2Z-3442-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Comparative genomics of 28 Salmonella enterica isolates: evidence for CRISPR-mediated adaptive sublineage evolution."
    Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G., Leclerc J.E., Ravel J., Cebula T.A.
    J. Bacteriol. 193:3556-3568(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CT_02021853.

Entry informationi

Entry nameiUXAC_SALDC
AccessioniPrimary (citable) accession number: B5FV01
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 14, 2008
Last modified: November 11, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.