B5FTB3 (RSMC_SALDC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase C
EC=2.1.1.172

Alternative name(s):
16S rRNA m2G1207 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RsmC

Gene names

Name:	rsmC
Ordered Locus Names:	SeD_A4970

Organism

Salmonella dublin (strain CT_02021853) [Complete proteome] [HAMAP]

Taxonomic identifier

439851 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella dublin

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle By similarity. HAMAP MF_01862
Catalytic activity	S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1207) in 16S rRNA. HAMAP MF_01862
Subunit structure	Monomer By similarity. HAMAP MF_01862
Subcellular location	Cytoplasm Potential HAMAP MF_01862.
Sequence similarities	Belongs to the methyltransferase superfamily. RsmC family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nucleic acid binding Inferred from electronic annotation. Source: InterPro rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 342	342	Ribosomal RNA small subunit methyltransferase C HAMAP MF_01862		PRO_0000369754

Sequences

	Sequence		Length	Mass (Da)
	B5FTB3 [UniParc]. Last modified October 14, 2008. Version 1. Checksum: F034BFD4CBEBE00F	FASTA	342	37,616
	10 20 30 40 50 60 MSAFTPASEV LLRHSDDFEQ SRILFAGDLQ DDLPARFECA ASRAHTQQFH HWQVLSRQMG 70 80 90 100 110 120 DNVRFSLVAQ ASDVADCDTL IYYWPKNKPE AQFQLMNILS LMPSGVDVFV VGENRSGVRS 130 140 150 160 170 180 AEPMLADYAP LNKVDSARRC GLYHGRLEKQ PQFSLESWWA EYNIDGLTIK TLPGVFSRDG 190 200 210 220 230 240 LDVGSQLLLS TLTPHTKGKV LDVGCGAGVL SAALASHSPK VRLTLCDVSA PAVEASRATL 250 260 270 280 290 300 AANGLEGEVF ASNVFSEVKG RFDMIISNPP FHDGMQTSLD AAQTLIRGAV RHLNSGGELR 310 320 330 340 IVANAFLPYP KILDETFGFH EVIAQTGRFK VYRTVMTRQA KK

References

[1]

"Complete genome of Salmonella dublin strain CT_02021853." Ravel J., Fricke W.F., White D., McDermott P., Mammel M., Rosovitz M., Leclerc J., Cebula T., Sebastian Y. Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CT_02021853.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001144 Genomic DNA. Translation: ACH73924.1.
RefSeq	YP_002218430.1. NC_011205.1.
3D structure databases
ProteinModelPortal	B5FTB3.
SMR	B5FTB3. Positions 3-336.
ModBase	Search...
Protein-protein interaction databases
STRING	B5FTB3.
Proteomic databases
PRIDE	B5FTB3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6875850.
GenomeReviews	Gene locus SeD_A4970 in contig CP001144_GR.
KEGG	sed:SeD_A4970.
PATRIC	18497986. VBISalEnt111443_4857.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG296757.
OMA	TGKFKVY.
ProtClustDB	PRK09489.
Family and domain databases
HAMAP	MF_01862. 16SrRNA_methyltr_C. [Tree]
InterPro	IPR002052. DNA_methylase_N6_adenine_CS. IPR013675. Mtase_sm_N. IPR023543. rRNA_ssu_MeTfrase_C. IPR007848. Small_mtfrase. [Graphical view]
KO	K00564.
Pfam	PF05175. MTS. 1 hit. PF08468. MTS_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RSMC_SALDC

Accession

Primary (citable) accession number: B5FTB3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	October 14, 2008
Last modified:	January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program