true2009-03-242024-03-2774LUXS_SALDCComparative genomics of 28 Salmonella enterica isolates: evidence for CRISPR-mediated adaptive sublineage evolution.Fricke W.F.Mammel M.K.McDermott P.F.Tartera C.White D.G.Leclerc J.E.Ravel J.Cebula T.A.doi:10.1128/jb.00297-112011J. Bacteriol.1933556-3568NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]CT_02021853S-ribosylhomocysteinase (LuxS)LuxSLuxS_sfMetalloenz_LuxS/M16S-ribosylhomocysteinaseS-RIBOSYLHOMOCYSTEINE LYASES-RIBOSYLHOMOCYSTEINE LYASELuxSAI2LUXSPROTEINLuxS/MPP-like metallohydrolaseS-ribosylhomocysteine lyase4.4.1.21AI-2 synthesis proteinAutoinducer-2 production protein LuxSluxSSeD_A3125Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).Binds 1 Fe cation per subunit.Homodimer.Belongs to the LuxS family.S-ribosylhomocysteine lyase19308117154581282008-10-14119308d1058295cfbac316c936edfffa37f5d3MPLLDSFAVDHTRMQAPAVRVAKTMNTPHGDAITVFDLRFCIPNKEVMPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVQDQNQIPELNVYQCGTYQMHSLSEAQDIARHILERDVRVNSNKELALPKEKLQELHItrue