Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B5FQL1 (NUDC_SALDC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
NADH pyrophosphatase

EC=3.6.1.22
Gene names
Name:nudC
Ordered Locus Names:SeD_A4573
OrganismSalmonella dublin (strain CT_02021853) [Complete proteome] [HAMAP]
Taxonomic identifier439851 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Protein attributes

Sequence length257 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

NAD+ + H2O = AMP + NMN. HAMAP-Rule MF_00297

Cofactor

Divalent metal cations. Magnesium or manganese By similarity.

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00297

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00297

Sequence similarities

Belongs to the Nudix hydrolase family. NudC subfamily.

Contains 1 nudix hydrolase domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 257257NADH pyrophosphatase HAMAP-Rule MF_00297
PRO_1000115247

Regions

Domain125 – 248124Nudix hydrolase
Motif159 – 18022Nudix box HAMAP-Rule MF_00297

Sites

Metal binding981Zinc By similarity
Metal binding1011Zinc By similarity
Metal binding1161Zinc By similarity
Metal binding1191Zinc By similarity
Metal binding1741Divalent metal cation By similarity
Metal binding1781Divalent metal cation By similarity

Sequences

Sequence LengthMass (Da)Tools
B5FQL1 [UniParc].

Last modified October 14, 2008. Version 1.
Checksum: 19B99052BD428C78

FASTA25729,607
        10         20         30         40         50         60 
MDRIIEKLES GWWIVSHEQK LWLPYGELPH GLAANFDLVG QRALRIGEWQ GEPVWLVLQH 

        70         80         90        100        110        120 
RRHDMGSVRQ VIDQDAGLFQ LAGRGVQLAE FYRSHKFCGY CGHPMHPSKT EWAMLCSHCR 

       130        140        150        160        170        180 
ERYYPQIAPC IIVAIRREDS ILLAQHVRHR NGVHTVLAGF VEVGETLEQA VAREVMEESG 

       190        200        210        220        230        240 
IKVKNLRYVT SQPWPFPQSL MTAFMAEYDS GEIVIDPKEL LEANWYRYDD LPLLPPPGTV 

       250 
ARRLIEDTVA MCRAEYD 

« Hide

References

[1]"Complete genome of Salmonella dublin strain CT_02021853."
Ravel J., Fricke W.F., White D., McDermott P., Mammel M., Rosovitz M., Leclerc J., Cebula T., Sebastian Y.
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CT_02021853.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001144 Genomic DNA. Translation: ACH74052.1.
RefSeqYP_002218082.1. NC_011205.1.

3D structure databases

ProteinModelPortalB5FQL1.
SMRB5FQL1. Positions 1-257.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING439851.SeD_A4573.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACH74052; ACH74052; SeD_A4573.
PATRIC18497188. VBISalEnt111443_4472.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2816.
HOGENOMHOG000247937.
OMAACLCHHC.
OrthoDBEOG6S26JD.
ProtClustDBPRK00241.

Enzyme and pathway databases

BioCycSENT439851:GH2Z-4516-MONOMER.

Family and domain databases

Gene3D3.90.79.10. 1 hit.
HAMAPMF_00297. Nudix_NudC.
InterProIPR022925. NADH_pyroPase_NudC.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
IPR015376. Znr_NADH_PPase.
[Graphical view]
PfamPF00293. NUDIX. 1 hit.
PF09297. zf-NADH-PPase. 1 hit.
[Graphical view]
SUPFAMSSF55811. SSF55811. 2 hits.
PROSITEPS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNUDC_SALDC
AccessionPrimary (citable) accession number: B5FQL1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: October 14, 2008
Last modified: April 16, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families