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Protein

Small heat shock protein IbpB

Gene

ibpB

Organism
Salmonella dublin (strain CT_02021853)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Enzyme and pathway databases

BioCyciSENT439851:GH2Z-4147-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Small heat shock protein IbpBUniRule annotation
Alternative name(s):
16 kDa heat shock protein BUniRule annotation
Gene namesi
Name:ibpBUniRule annotation
Ordered Locus Names:SeD_A4197
OrganismiSalmonella dublin (strain CT_02021853)
Taxonomic identifieri439851 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 142142Small heat shock protein IbpBPRO_1000189108Add
BLAST

Proteomic databases

PRIDEiB5FMC8.

Interactioni

Subunit structurei

Homodimer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to oligomers at high temperatures or high ionic concentrations. The decrease in size of the multimers is accompanied by an increase in chaperone activity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB5FMC8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

The N- and C-terminal flexible termini are involved in oligomerization and in the binding of non-native substrate proteins, and are essential for chaperone activity.UniRule annotation

Sequence similaritiesi

Belongs to the small heat shock protein (HSP20) family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000251750.
KOiK04081.
OMAiRQFQRSF.
OrthoDBiEOG65TRT6.

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
HAMAPiMF_02001. HSP20_IbpB.
InterProiIPR002068. A-crystallin/Hsp20_dom.
IPR031107. HSP20.
IPR008978. HSP20-like_chaperone.
IPR022848. HSP20_IbpB.
[Graphical view]
PANTHERiPTHR11527. PTHR11527. 1 hit.
PfamiPF00011. HSP20. 1 hit.
[Graphical view]
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS01031. HSP20. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5FMC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNYDLSPLL RQWIGFDKLA NALQNSGESQ SFPPYNIEKS DDNHYRITLA
60 70 80 90 100
LAGFRQEDLD IQLEGTRLTV KGTPEQPENE PKWLHQGLVM QPFSLSFTLA
110 120 130 140
ENMEVSGATF TNGLLHIDLT RNEPETIAPQ RIAINERSAL NS
Length:142
Mass (Da):16,084
Last modified:October 14, 2008 - v1
Checksum:i6F7375C7CB2AE157
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001144 Genomic DNA. Translation: ACH75601.1.
RefSeqiWP_001246919.1. NC_011205.1.

Genome annotation databases

EnsemblBacteriaiACH75601; ACH75601; SeD_A4197.
KEGGised:SeD_A4197.
PATRICi18496460. VBISalEnt111443_4132.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001144 Genomic DNA. Translation: ACH75601.1.
RefSeqiWP_001246919.1. NC_011205.1.

3D structure databases

ProteinModelPortaliB5FMC8.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiB5FMC8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACH75601; ACH75601; SeD_A4197.
KEGGised:SeD_A4197.
PATRICi18496460. VBISalEnt111443_4132.

Phylogenomic databases

HOGENOMiHOG000251750.
KOiK04081.
OMAiRQFQRSF.
OrthoDBiEOG65TRT6.

Enzyme and pathway databases

BioCyciSENT439851:GH2Z-4147-MONOMER.

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
HAMAPiMF_02001. HSP20_IbpB.
InterProiIPR002068. A-crystallin/Hsp20_dom.
IPR031107. HSP20.
IPR008978. HSP20-like_chaperone.
IPR022848. HSP20_IbpB.
[Graphical view]
PANTHERiPTHR11527. PTHR11527. 1 hit.
PfamiPF00011. HSP20. 1 hit.
[Graphical view]
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS01031. HSP20. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative genomics of 28 Salmonella enterica isolates: evidence for CRISPR-mediated adaptive sublineage evolution."
    Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G., Leclerc J.E., Ravel J., Cebula T.A.
    J. Bacteriol. 193:3556-3568(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CT_02021853.

Entry informationi

Entry nameiIBPB_SALDC
AccessioniPrimary (citable) accession number: B5FMC8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: October 14, 2008
Last modified: November 11, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.