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B5FJD4 (ASTE_SALDC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Succinylglutamate desuccinylase

EC=3.5.1.96
Gene names
Name:astE
Ordered Locus Names:SeD_A2039
OrganismSalmonella dublin (strain CT_02021853) [Complete proteome] [HAMAP]
Taxonomic identifier439851 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Protein attributes

Sequence length322 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transforms N(2)-succinylglutamate into succinate and glutamate By similarity. HAMAP-Rule MF_00767

Catalytic activity

N-succinyl-L-glutamate + H2O = succinate + L-glutamate. HAMAP-Rule MF_00767

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00767

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 5/5. HAMAP-Rule MF_00767

Sequence similarities

Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 322322Succinylglutamate desuccinylase HAMAP-Rule MF_00767
PRO_1000133639

Sites

Active site2101 Potential
Metal binding531Zinc By similarity
Metal binding561Zinc By similarity
Metal binding1471Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
B5FJD4 [UniParc].

Last modified October 14, 2008. Version 1.
Checksum: E2884FC6C1C232C2

FASTA32235,634
        10         20         30         40         50         60 
MDNFLALTLS GTTPRVTQGK SAGFRWRWLG HGLLELTPDA PVDRALILSA GIHGNETAPV 

        70         80         90        100        110        120 
EMLDKLLSAL FSGSLTLTWR VLVVLGNPQA LAAGIRYCHS DMNRMFGGRW QSFAESDETR 

       130        140        150        160        170        180 
RARELELSLE TFFSSGHARV RWHLDLHTAI RGSHHLRFGV LPQRDRPWET DFLAWLGAAG 

       190        200        210        220        230        240 
LEALVFHQAP GGTFTHFSSE HFGALSCALE LGKALPFRQN DLTQFNVTSQ ALSALLSGVE 

       250        260        270        280        290        300 
TSTSFSPPLR YRVVSQITRH SDKFALYMDA QTLNFTAFAK GTLLAEEGDK RVTVTHDVEY 

       310        320 
VLFPNPSVAC GLRAGLMLER LP 

« Hide

References

[1]"Complete genome of Salmonella dublin strain CT_02021853."
Ravel J., Fricke W.F., White D., McDermott P., Mammel M., Rosovitz M., Leclerc J., Cebula T., Sebastian Y.
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CT_02021853.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001144 Genomic DNA. Translation: ACH74276.1.
RefSeqYP_002215819.1. NC_011205.1.

3D structure databases

ProteinModelPortalB5FJD4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING439851.SeD_A2039.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACH74276; ACH74276; SeD_A2039.
PATRIC18492240. VBISalEnt111443_2064.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2988.
HOGENOMHOG000280300.
OMATAPIEIC.
OrthoDBEOG613070.
ProtClustDBPRK05324.

Enzyme and pathway databases

BioCycSENT439851:GH2Z-2022-MONOMER.
UniPathwayUPA00185; UER00283.

Family and domain databases

HAMAPMF_00767. Arg_catab_AstE.
InterProIPR007036. Aste_AspA.
IPR016681. SuccinylGlu_desuccinylase.
[Graphical view]
PfamPF04952. AstE_AspA. 1 hit.
[Graphical view]
TIGRFAMsTIGR03242. arg_catab_astE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameASTE_SALDC
AccessionPrimary (citable) accession number: B5FJD4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 14, 2008
Last modified: February 19, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways