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Protein

Glutaminase

Gene

glsA

Organism
Salmonella dublin (strain CT_02021853)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei66SubstrateUniRule annotation1
Binding sitei117SubstrateUniRule annotation1
Binding sitei161SubstrateUniRule annotation1
Binding sitei168SubstrateUniRule annotation1
Binding sitei192SubstrateUniRule annotation1
Binding sitei244SubstrateUniRule annotation1
Binding sitei262Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:SeD_A1810
OrganismiSalmonella dublin (strain CT_02021853)
Taxonomic identifieri439851 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001157051 – 308GlutaminaseAdd BLAST308

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB5FHM8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000216890.
KOiK01425.
OMAiVNSIMAT.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

B5FHM8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAWAMDNAIL ETILQRVRPL IGQGKVAAYI PALASVEGSK LGIAICTVDG
60 70 80 90 100
QHYQAGDAHE RFSIQSISKV LSLVVTMRHY PEEEIWQRVG KDPSGSPFNS
110 120 130 140 150
LVQLEMEQGI PRNPFINAGA LVVCDMLQGR LSAPRQRMLE VVRALCGVSD
160 170 180 190 200
ITYDATVARS EFEHSARNAA IAWLMKSFGN FHHDVPTVLQ NYFHYCALKM
210 220 230 240 250
SCMELARTFV FLANQGEAFH LDEPVVTPMQ ARQINALMAT SGMYQNAGEF
260 270 280 290 300
AWRVGLPAKS GVGGGIVAIV PHEMAIAVWS PELDPAGNSL AGIAALEQLT

QTLGRSVY
Length:308
Mass (Da):33,613
Last modified:October 14, 2008 - v1
Checksum:i057F37C3DCE86653
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001144 Genomic DNA. Translation: ACH73720.1.
RefSeqiWP_000312239.1. NC_011205.1.

Genome annotation databases

EnsemblBacteriaiACH73720; ACH73720; SeD_A1810.
KEGGised:SeD_A1810.
PATRICi18491783. VBISalEnt111443_1838.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001144 Genomic DNA. Translation: ACH73720.1.
RefSeqiWP_000312239.1. NC_011205.1.

3D structure databases

ProteinModelPortaliB5FHM8.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACH73720; ACH73720; SeD_A1810.
KEGGised:SeD_A1810.
PATRICi18491783. VBISalEnt111443_1838.

Phylogenomic databases

HOGENOMiHOG000216890.
KOiK01425.
OMAiVNSIMAT.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLSA_SALDC
AccessioniPrimary (citable) accession number: B5FHM8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: October 14, 2008
Last modified: November 2, 2016
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.