B5FCP7 (CMOB_VIBFM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
tRNA (mo5U34)-methyltransferase
EC=2.1.1.-

Gene names

Name:	cmoB
Ordered Locus Names:	VFMJ11_0988

Organism

Vibrio fischeri (strain MJ11) [Complete proteome] [HAMAP]

Taxonomic identifier

388396 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Aliivibrio › Vibrio fischeri

Protein attributes

Sequence length	324 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA By similarity. HAMAP-Rule MF_01590
Sequence similarities	Belongs to the methyltransferase superfamily. CmoB family.

Ontologies

Keywords
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tRNA wobble uridine modification Inferred from electronic annotation. Source: InterPro
Molecular_function	S-adenosylmethionine-dependent methyltransferase activity Inferred from electronic annotation. Source: HAMAP tRNA (uracil) methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 324	324	tRNA (mo5U34)-methyltransferase HAMAP-Rule MF_01590		PRO_1000201315

Sequences

	Sequence		Length	Mass (Da)
	B5FCP7 [UniParc]. Last modified October 14, 2008. Version 1. Checksum: BDD28AE32F4388E7	FASTA	324	37,249
	10 20 30 40 50 60 MFNFANFYQL LAQDTVLQPW LNTLPQQLTD WQNAEHGDIE RWIKALKKIP EGCADNIDLK 70 80 90 100 110 120 SSVTLSNNTP LIDGERKKLE NLLQTFHPWR KGPFTVHDIH IDTEWRSDWK WDRLLPHITP 130 140 150 160 170 180 LKNRSVLDVG CGNGYHMWRM LGEEARLCVG IDPSHLFLIQ FEAIRKLMGN DQRAHLLPLG 190 200 210 220 230 240 IEQLPELNAF DTVFSMGVLY HRRSPLDHLI QLKNQLVAGG ELVLETLVID GDENAVLMPV 250 260 270 280 290 300 DRYAQMRNVY FFPSARALKV WLESVGFVDV KIVDECVTTT GEQRSTEWMK HNSLPEYLDP 310 320 NDSTKTIEGH PAPKRAILIA KKPD

References

[1]

"Complete sequence of Vibrio fischeri strain MJ11." Mandel M.J., Stabb E.V., Ruby E.G., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C. Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MJ11.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001139 Genomic DNA. Translation: ACH65286.1.
RefSeq	YP_002155710.1. NC_011184.1.
3D structure databases
ProteinModelPortal	B5FCP7.
ModBase	Search...
Protein-protein interaction databases
STRING	388396.VFMJ11_0988.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACH65286; ACH65286; VFMJ11_0988.
GeneID	6806458.
KEGG	vfm:VFMJ11_0988.
PATRIC	20120439. VBIVibFis37164_0938.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0500.
HOGENOM	HOG000218456.
KO	K15257.
OMA	WRKGPFE.
ProtClustDB	PRK15068.
Family and domain databases
HAMAP	MF_01590. tRNA_methyltr_CmoB.
InterPro	IPR010017. tRNA_mo5U34_MeTrfase. [Graphical view]
Pfam	PF08003. Methyltransf_9. 1 hit. [Graphical view]
TIGRFAMs	TIGR00452. TIGR00452. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CMOB_VIBFM

Accession

Primary (citable) accession number: B5FCP7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	October 14, 2008
Last modified:	May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program