B5FAS8 (ARGA_VIBFM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Amino-acid acetyltransferase
EC=2.3.1.1

Alternative name(s):
N-acetylglutamate synthase
Short name=AGS
Short name=NAGS

Gene names

Name:	argA
Ordered Locus Names:	VFMJ11_0599

Organism

Vibrio fischeri (strain MJ11) [Complete proteome] [HAMAP]

Taxonomic identifier

388396 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Aliivibrio

Protein attributes

Sequence length	446 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate. HAMAP MF_01105
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4. HAMAP MF_01105
Subcellular location	Cytoplasm By similarity HAMAP MF_01105.
Sequence similarities	Belongs to the acetyltransferase family. ArgA subfamily. Contains 1 N-acetyltransferase domain.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	acetyl-CoA:L-glutamate N-acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 446	446	Amino-acid acetyltransferase HAMAP MF_01105		PRO_1000137054
Regions
	Domain	299 – 431	133	N-acetyltransferase

Sequences

	Sequence		Length	Mass (Da)
	B5FAS8 [UniParc]. Last modified October 14, 2008. Version 1. Checksum: 96BCA559C0F9FD69	FASTA	446	49,518
	10 20 30 40 50 60 MKFRSTALVK GFRQSAPYVN AHRDKTVVIM LGGEAIADPN FANIVNDIAL LNSLGLRIVI 70 80 90 100 110 120 VYGTRPQMRS LLKQTEHHAP FHKGIRITDE QTLELVKQIA GQLQLDITAR LSMSLNNTPM 130 140 150 160 170 180 AGAQINVISG NFVIAQPLGV DDGIDYCHSG RVRRIDTQGI NRMLDQQSIV LLGPVASSVT 190 200 210 220 230 240 GECFNLLSED VATQLAIRLN ADKLIGFCSE QGVLNEKGQI LAELFPSEAE EILQRLEKEL 250 260 270 280 290 300 TPENGKLTGT MRFLKGAISA CKAGVPRSHL ISYKEDGALI QELFSFDGIG TQVVMASSEQ 310 320 330 340 350 360 VRDAEIDDIG GILDLIRPLE EEGILVRRSR EQLEQEIAQF TIIEKDGLVI ACAALYPFPE 370 380 390 400 410 420 EGMAEMGCVA VHPDYRDGDR GVILLNRLRA KAKQYKLSQL FVLTTRSLHW FREQGFIEVD 430 440 VSHLPMKKQK LYNFQRKSKI LVLKGL

References

[1]

"Complete sequence of Vibrio fischeri strain MJ11." Mandel M.J., Stabb E.V., Ruby E.G., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C. Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MJ11.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001139 Genomic DNA. Translation: ACH66226.1.
RefSeq	YP_002155342.1. NC_011184.1.
3D structure databases
ProteinModelPortal	B5FAS8.
ModBase	Search...
Protein-protein interaction databases
STRING	B5FAS8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6805414.
GenomeReviews	Gene locus VFMJ11_0599 in contig CP001139_GR.
KEGG	vfm:VFMJ11_0599.
PATRIC	20119663. VBIVibFis37164_0571.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG545264.
OMA	AFNLAME.
ProtClustDB	PRK05279.
Family and domain databases
HAMAP	MF_01105. N-acetyl_glu_synth. [Tree]
InterPro	IPR000182. AcTrfase_GCN5-related_dom. IPR016181. Acyl_CoA_acyltransferase. IPR001048. Asp/Glu/Uridylate_kinase. IPR010167. NH2A_AcTrfase_ArgA. [Graphical view]
Gene3D	G3DSA:3.40.1160.10. Aa_kinase. 1 hit. G3DSA:3.40.630.30. Acyl_CoA_acyltransferase. 1 hit.
KO	K14682.
Pfam	PF00696. AA_kinase. 1 hit. PF00583. Acetyltransf_1. 1 hit. [Graphical view]
PIRSF	PIRSF000423. ArgA. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit. SSF55729. Acyl_CoA_acyltransferase. 1 hit.
TIGRFAMs	TIGR01890. N-Ac-Glu-synth. 1 hit.
PROSITE	PS51186. GNAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ARGA_VIBFM

Accession

Primary (citable) accession number: B5FAS8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	October 14, 2008
Last modified:	January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program