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B5F9R6

- GLSA_VIBFM

UniProt

B5F9R6 - GLSA_VIBFM

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Protein
Glutaminase
Gene
glsA, VFMJ11_0423
Organism
Vibrio fischeri (strain MJ11)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei64 – 641Substrate By similarity
Binding sitei115 – 1151Substrate By similarity
Binding sitei159 – 1591Substrate By similarity
Binding sitei166 – 1661Substrate By similarity
Binding sitei190 – 1901Substrate By similarity
Binding sitei242 – 2421Substrate By similarity
Binding sitei260 – 2601Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:VFMJ11_0423
OrganismiVibrio fischeri (strain MJ11)
Taxonomic identifieri388396 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
ProteomesiUP000001857: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306GlutaminaseUniRule annotation
PRO_1000115711Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi388396.VFMJ11_0423.

Structurei

3D structure databases

ProteinModelPortaliB5F9R6.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

B5F9R6-1 [UniParc]FASTAAdd to Basket

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MKPTKQILED ILDEVRPLIG QGKVADYIPA LACVPNDKLG IAVFTNDGEM    50
LTAGDATECF SIQSISKALS LTLAMELYQP EELWQRVGKE PSGQAFNSLI 100
QLEMEQGVPR NPFINAGAIV ISDMLYSRFS APKHRLLEFV RKLSGNEHII 150
YDRVVANSEM DHSDRNASIA YLMRSFGNFD NEVMPVLKNY FHACALSMNC 200
VDLARTFGYL ANKGIQPGIS EPIVTPMQCK QINALMATCG LYDGAGEFAY 250
RVGMPGKSGV GGGIIAIVPG EMTIAVWSPE LDPSGNSLAG TKALELLSER 300
IGRSIF 306
Length:306
Mass (Da):33,328
Last modified:October 14, 2008 - v1
Checksum:i12EF588A611B08BB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001139 Genomic DNA. Translation: ACH66312.1.
RefSeqiWP_012533640.1. NC_011184.1.
YP_002155179.1. NC_011184.1.

Genome annotation databases

EnsemblBacteriaiACH66312; ACH66312; VFMJ11_0423.
GeneIDi6806114.
KEGGivfm:VFMJ11_0423.
PATRICi20119307. VBIVibFis37164_0408.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001139 Genomic DNA. Translation: ACH66312.1 .
RefSeqi WP_012533640.1. NC_011184.1.
YP_002155179.1. NC_011184.1.

3D structure databases

ProteinModelPortali B5F9R6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 388396.VFMJ11_0423.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACH66312 ; ACH66312 ; VFMJ11_0423 .
GeneIDi 6806114.
KEGGi vfm:VFMJ11_0423.
PATRICi 20119307. VBIVibFis37164_0408.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Vibrio fischeri strain MJ11."
    Mandel M.J., Stabb E.V., Ruby E.G., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.
    Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MJ11.

Entry informationi

Entry nameiGLSA_VIBFM
AccessioniPrimary (citable) accession number: B5F9R6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: October 14, 2008
Last modified: September 3, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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