Reviewed, UniProtKB/Swiss-Prot B5F621 (UXUA_SALA4)

Names and origin

Protein names

Recommended name:
    Mannonate dehydratase
    EC=4.2.1.8
Alternative name(s):
    D-mannonate hydrolase

Gene names

Name:	uxuA
Ordered Locus Names:	SeAg_B3307

Organism

Salmonella agona (strain SL483) [Complete proteome] [HAMAP]

Taxonomic identifier

454166 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella enterica subsp. enterica serovar Agona

Protein attributes

Sequence length	394 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106
Sequence similarities	Belongs to the mannonate dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	mannonate dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 394	394	Mannonate dehydratase HAMAP MF_00106		PRO_1000094217

Sequences

	Sequence		Length	Mass (Da)
	B5F621-1 [UniParc]. Last modified October 14, 2008. Version 1. Checksum: CA690041E17D119F	FASTA	394	44,937
	10 20 30 40 50 60 MKQTWRWYGP NDPVTLSDVR QAGATGVVTA LHHIPNGEIW SVDEIQKRKA IVEEAGLEWS 70 80 90 100 110 120 VVESVPIHED IKTHTGQYDL WIKNYQQTLR NLAQCGIYTV CYNFMPVLDW TRTDLEYVLP 130 140 150 160 170 180 DGSKALRFDQ IEFAAFELHI LKRPGAEADY TAEEIAQAER RFATMSEEDK ARLTRNIIAG 190 200 210 220 230 240 LPGAEEGYTL DQFRQHLATY KDIDKAKLRE HFAYFLKAII PVADEVGVRM AVHPDDPPRP 250 260 270 280 290 300 ILGLPRIVST IEDMQWMVET VNSMANGFTM CTGSYGVRAD NDLVDMIKQF GPRIYFTHLR 310 320 330 340 350 360 STLREENPKT FHEAAHLHGD VDMYEVVKAI VEEEHRRKAE GSDDLIPMRP DHGHQMLDDL 370 380 390 KKKTNPGYSA IGRLKGLAEV RGVELAIQRA FFSK

References

[1]	"Complete genome of Salmonella agona strain SL483." Ravel J., Fricke W.F., White D., McDermott P., Mammel M., Rosovitz M., Leclerc J., Cebula T., Sebastian Y. Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001138 Genomic DNA. Translation: ACH49973.1.
RefSeq	YP_002148055.1.
3D structure databases
SMR	B5F621. Positions 1-389.
ModBase	Search...
Proteomic databases
PRIDE	B5F621.
Genome annotation databases
GeneID	6796879.
GenomeReviews	Gene locus SeAg_B3307 in contig CP001138_GR.
KEGG	sea:SeAg_B3307.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG585927.
OMA	VHEEIKT.
Family and domain databases
HAMAP	MF_00106. UxuA. [Tree]
InterPro	IPR004628. Man_deHydtase. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Gene3D	G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
Pfam	PF03786. UxuA. 1 hit. [Graphical view]
PIRSF	PIRSF016049. Man_dehyd. 1 hit.
TIGRFAMs	TIGR00695. uxuA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UXUA_SALA4

Accession

Primary (citable) accession number: B5F621

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	October 14, 2008
Last modified:	February 9, 2010
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)