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B5F610

- GLSA_SALA4

UniProt

B5F610 - GLSA_SALA4

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Protein

Glutaminase

Gene

glsA

Organism
Salmonella agona (strain SL483)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei66 – 661SubstrateUniRule annotation
Binding sitei117 – 1171SubstrateUniRule annotation
Binding sitei161 – 1611SubstrateUniRule annotation
Binding sitei168 – 1681SubstrateUniRule annotation
Binding sitei192 – 1921SubstrateUniRule annotation
Binding sitei244 – 2441SubstrateUniRule annotation
Binding sitei262 – 2621Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciSENT454166:GHBA-1632-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:SeAg_B1645
OrganismiSalmonella agona (strain SL483)
Taxonomic identifieri454166 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000008819: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 308308GlutaminasePRO_1000115704Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi454166.SeAg_B1645.

Structurei

3D structure databases

ProteinModelPortaliB5F610.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

B5F610-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MARAMDNAIL ETILQRVRPL IGQGKVADYI PALASVEGSK LGIAICTVDG
60 70 80 90 100
QHYQAGDAHE RFSIQSISKV LSLVVAMRHY PEEEIWQRVG KDPSGSPFNS
110 120 130 140 150
LVQLEMEQGI PRNPFINAGA LVVCDMLQGR LSAPRQRMLE VVRALCGVSD
160 170 180 190 200
ITYDVTVARS EFEHSARNAA IAWLMKSFGN FHHDVPTVLQ NYFHYCALKM
210 220 230 240 250
SCMELARTFV FLANQGEAFH LDEPVVTPMQ ARQINALMAT SGMYQNAGEF
260 270 280 290 300
AWRVGLPAKS GVGGGIVAIV PHEMAIAVWS PELDPAGNSL AGIAALEQLT

QTLGRSVY
Length:308
Mass (Da):33,625
Last modified:October 14, 2008 - v1
Checksum:i02BF79CA7FB64129
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001138 Genomic DNA. Translation: ACH50241.1.
RefSeqiYP_002146516.1. NC_011149.1.

Genome annotation databases

EnsemblBacteriaiACH50241; ACH50241; SeAg_B1645.
PATRICi18481578. VBISalEnt65316_1605.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001138 Genomic DNA. Translation: ACH50241.1 .
RefSeqi YP_002146516.1. NC_011149.1.

3D structure databases

ProteinModelPortali B5F610.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 454166.SeAg_B1645.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACH50241 ; ACH50241 ; SeAg_B1645 .
PATRICi 18481578. VBISalEnt65316_1605.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci SENT454166:GHBA-1632-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Comparative genomics of 28 Salmonella enterica isolates: evidence for CRISPR-mediated adaptive sublineage evolution."
    Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G., Leclerc J.E., Ravel J., Cebula T.A.
    J. Bacteriol. 193:3556-3568(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SL483.

Entry informationi

Entry nameiGLSA_SALA4
AccessioniPrimary (citable) accession number: B5F610
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: October 14, 2008
Last modified: October 1, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3