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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Salmonella agona (strain SL483)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciSENT454166:GHBA-2637-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:SeAg_B2661
OrganismiSalmonella agona (strain SL483)
Taxonomic identifieri454166 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000008819 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 449449Exodeoxyribonuclease 7 large subunitPRO_1000122080Add
BLAST

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229265.
KOiK03601.
OMAiENAQVRC.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

B5F187-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSSQTSSIF TVSRLNQTVR LLLEQEMGQV WISGEISNFT QPASGHWYFT
60 70 80 90 100
LKDDTAQVRC AMFRNSNRRV TFRPQHGQQV LVRANITLYE PRGDYQIIAE
110 120 130 140 150
SMQPAGEGLL QQKYEQLKAK LHSEGLFDQQ HKQPLPSPAH CVGVITSKTG
160 170 180 190 200
AALHDILHVL KRRDPSLPVI IYPTAVQGDD APGQIVRAIE LANARGECDV
210 220 230 240 250
LIVGRGGGSL EDLWSFNDER VARAIFASRI PVVSAVGHET DVTIADFVAD
260 270 280 290 300
LRAPTPSAAA EIVSRNQQEL LRRIQSAQQR LGMAMDYYLA NRSRRFTQIF
310 320 330 340 350
HRLQQQHPQL RLARQQTALE RLRQRMGFAL EARIKQATQR QQRVSQRLSQ
360 370 380 390 400
QNPQPRIHRA QSRIQQLEYR LTENIRSRLS EQRERFGNAV THLEAVSPLA
410 420 430 440
TLARGYTVST TTNGKVLKKI KQVKAGDIMT TRLEDGWLES EVKSVTPGT
Length:449
Mass (Da):50,706
Last modified:October 14, 2008 - v1
Checksum:i5AC3AA22314D4447
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001138 Genomic DNA. Translation: ACH51839.1.
RefSeqiWP_000953158.1. NC_011149.1.

Genome annotation databases

EnsemblBacteriaiACH51839; ACH51839; SeAg_B2661.
KEGGisea:SeAg_B2661.
PATRICi18483610. VBISalEnt65316_2604.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001138 Genomic DNA. Translation: ACH51839.1.
RefSeqiWP_000953158.1. NC_011149.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACH51839; ACH51839; SeAg_B2661.
KEGGisea:SeAg_B2661.
PATRICi18483610. VBISalEnt65316_2604.

Phylogenomic databases

HOGENOMiHOG000229265.
KOiK03601.
OMAiENAQVRC.

Enzyme and pathway databases

BioCyciSENT454166:GHBA-2637-MONOMER.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiEX7L_SALA4
AccessioniPrimary (citable) accession number: B5F187
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 14, 2008
Last modified: September 7, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.