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Protein

Ribosomal RNA large subunit methyltransferase F

Gene

rlmF

Organism
Vibrio fischeri (strain MJ11)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 1618 of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase FUniRule annotation (EC:2.1.1.181UniRule annotation)
Alternative name(s):
23S rRNA mA1618 methyltransferaseUniRule annotation
rRNA adenine N-6-methyltransferaseUniRule annotation
Gene namesi
Name:rlmFUniRule annotation
Ordered Locus Names:VFMJ11_A1248
OrganismiVibrio fischeri (strain MJ11)
Taxonomic identifieri388396 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
Proteomesi
  • UP000001857 Componenti: Chromosome II

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 319319Ribosomal RNA large subunit methyltransferase FPRO_1000188538Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliB5EVS5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. METTL16/RlmF family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.
OrthoDBiEOG6742SX.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 2 hits.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

B5EVS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNIKSNVTK KSLHPRNKHT GNYDFPALIK ACAELKPFVE TNQYGNESIN
60 70 80 90 100
FSDPQAVKAL NKALLAHFYN VPFWDIPQGY LCPPIPGRAD YIHNIADLLA
110 120 130 140 150
ITNEGTIPTG KKVKGLDVGV GANCVYPIIG NREYQWSFVG SDIDPQSIKM
160 170 180 190 200
ASFIANNNPS LKGIECRLQK NEENIFKGII KPTEFFDFTM CNPPFHASEA
210 220 230 240 250
EATAGTERKQ KNLAANKAKK GHSFQEMQNA KALNFGGQKA ELWCEGGELA
260 270 280 290 300
FILKMAQQSR EFSLQVQWFT TLISKKENVA ELYKELEKIG VKTIKTIEMA
310
QGQKISRFVA WTYQANVNL
Length:319
Mass (Da):35,714
Last modified:October 14, 2008 - v1
Checksum:i35F5C60D32F9EE4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001133 Genomic DNA. Translation: ACH64154.1.
RefSeqiWP_012535278.1. NC_011186.1.

Genome annotation databases

EnsemblBacteriaiACH64154; ACH64154; VFMJ11_A1248.
KEGGivfm:VFMJ11_A1248.
PATRICi20126700. VBIVibFis37164_3970.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001133 Genomic DNA. Translation: ACH64154.1.
RefSeqiWP_012535278.1. NC_011186.1.

3D structure databases

ProteinModelPortaliB5EVS5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACH64154; ACH64154; VFMJ11_A1248.
KEGGivfm:VFMJ11_A1248.
PATRICi20126700. VBIVibFis37164_3970.

Phylogenomic databases

HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.
OrthoDBiEOG6742SX.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 2 hits.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Vibrio fischeri strain MJ11."
    Mandel M.J., Stabb E.V., Ruby E.G., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.
    Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MJ11.

Entry informationi

Entry nameiRLMF_VIBFM
AccessioniPrimary (citable) accession number: B5EVS5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: October 14, 2008
Last modified: November 11, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.