B5ET96THIM_ALIFMHydroxyethylthiazole kinase2.7.1.504-methyl-5-beta-hydroxyethylthiazole kinaseTH kinaseThz kinasethiMVFMJ11_A0359Aliivibrio fischeri (strain MJ11)Vibrio fischeriBacteriaPseudomonadotaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrioComplete sequence of Vibrio fischeri strain MJ11.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+)Mg(2+)Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1.Belongs to the Thz kinase family.ATP-bindingKinaseMagnesiumMetal-bindingNucleotide-bindingThiamine biosynthesisTransferasesubstrateATPATPsubstrateMNIQYIVECLALLREKKPLVVNITNYVVMNNTANALLALGASPIMAHSQQEMAEMMSFSGALVINIGTLDSVWTPRMHFAVEQANLNNKVVVLDPVGCGASQLRTQVARQIAEAANKLIIRANASEVIALAGENAQSKGVDALDSSDSAVGAACYVAQKYQCSVVISGETDYIVTQDAQYKLNNGHAMMPFVTGMGCTHTALTGAFAAIGDESGVVATAVLGVAGEIAAEQSAGPGSLQMNLLDTLYQLDEETLTRRLKLTVNA
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