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B5EQR0 (B5EQR0_ACIF5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase HAMAP MF_00387
Short name=UDP-N-acetylglucosamine acyltransferase HAMAP MF_00387
EC=2.3.1.129 HAMAP MF_00387
Gene names
Name:lpxA HAMAP MF_00387
Ordered Locus Names:Lferr_1172
OrganismAcidithiobacillus ferrooxidans (strain ATCC 53993) (Leptospirillum ferrooxidans (ATCC 53993)) [Complete proteome] [HAMAP]
Taxonomic identifier380394 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Acidithiobacillales › Acidithiobacillaceae › Acidithiobacillus

Protein attributes

Sequence length260 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00387 SAAS SAAS010137

Catalytic activity

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. HAMAP MF_00387 SAAS SAAS010137

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. HAMAP MF_00387 SAAS SAAS010137

Subunit structure

Homotrimer By similarity. HAMAP MF_00387 SAAS SAAS010137

Subcellular location

Cytoplasm By similarity HAMAP MF_00387 SAAS SAAS010137.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxA subfamily. HAMAP MF_00387

Sequences

Sequence LengthMass (Da)Tools
B5EQR0 [UniParc].

Last modified October 14, 2008. Version 1.
Checksum: AE3849DDF055ED3F

FASTA26027,586
        10         20         30         40         50         60 
MTVQIHPLAI VDSSVQIGEG CTIGPFAVIG AGVEIGDHCR IGANTVIEGP CRLGAHNQIF 

        70         80         90        100        110        120 
QFASVGTAPQ DLGYAGEPTT LEIGSHNTIR EFVTINRGTV KGGGTTRIGH HNLLMAYCHV 

       130        140        150        160        170        180 
AHDCSIGDQV VMANAATLAG HVSVEDHAIL GGLSAVHQYA RVGAHAILGG GTMAPLDIPP 

       190        200        210        220        230        240 
FMMAAGNHAS LHGINVRGLA RRGIPRETIL QIKRAYRLLF RSGLRLEDAM DEVSQRGLNA 

       250        260 
PEVAYLLDFI RNSRRGITRP

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References

[1]"Complete sequence of Acidithiobacillus ferrooxidans ATCC 53993."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Kuske C.R., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Borole A.P.
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 53993.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001132 Genomic DNA. Translation: ACH83410.1.
RefSeqYP_002219617.1. NC_011206.1.

3D structure databases

ProteinModelPortalB5EQR0.
ModBaseSearch...

Protein-protein interaction databases

STRINGB5EQR0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6877145.
GenomeReviewsGene locus Lferr_1172 in contig CP001132_GR.
KEGGafe:Lferr_1172.
PATRIC20659956. VBIAciFer6930_1183.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG659295.
OMAREFCTFN.

Family and domain databases

HAMAPMF_00387. LpxA.
[Tree]
InterProIPR001451. Hexapep_transf.
IPR010137. Lipid_A_lpxA.
IPR011004. Trimer_LpxA-like.
[Graphical view]
KOK00677.
PfamPF00132. Hexapep. 4 hits.
[Graphical view]
PIRSFPIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR01852. Lipid_A_lpxA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB5EQR0_ACIF5
AccessionPrimary (citable) accession number: B5EQR0
Entry history
Integrated into UniProtKB/TrEMBL: October 14, 2008
Last sequence update: October 14, 2008
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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