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Protein

Chaperone protein HscA homolog

Gene

hscA

Organism
Acidithiobacillus ferrooxidans (strain ATCC 53993) (Leptospirillum ferrooxidans (ATCC 53993))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein HscA homologUniRule annotation
Gene namesi
Name:hscAUniRule annotation
Ordered Locus Names:Lferr_0826
OrganismiAcidithiobacillus ferrooxidans (strain ATCC 53993) (Leptospirillum ferrooxidans (ATCC 53993))
Taxonomic identifieri380394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAcidithiobacilliaAcidithiobacillalesAcidithiobacillaceaeAcidithiobacillus
Proteomesi
  • UP000001856 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001316611 – 621Chaperone protein HscA homologAdd BLAST621

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi380394.Lferr_0826.

Structurei

3D structure databases

ProteinModelPortaliB5ENY5.
SMRiB5ENY5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C9I. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04044.
OMAiLRGIPAM.
OrthoDBiPOG091H067B.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00679. HscA. 1 hit.
InterProiView protein in InterPro
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
IPR010236. ISC_FeS_clus_asmbl_HscA.
PfamiView protein in Pfam
PF00012. HSP70. 1 hit.
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR01991. HscA. 1 hit.
PROSITEiView protein in PROSITE
PS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.

Sequencei

Sequence statusi: Complete.

B5ENY5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALMQIAEPG TAADPHQRRL AIGIDLGTTH SLVASVLSAV PTVMRDHDGK
60 70 80 90 100
YLLPSVVRYL GGGGIHVGYP AVAAAGQDPH NTIASAKRLM GRGHGDVQTL
110 120 130 140 150
AGHLPYDLVP GEGMVRLRTV AGEKSPVEVS AEILRVLKER AVETLGGEPE
160 170 180 190 200
GAVITVPAYF DEAQRQATKD AARLAGLNVL RLLAEPTAAA VAYGLDKGSE
210 220 230 240 250
GIFAIYDLGG GTFDISILRL QAGVFEVLAT AGDSALGGDD MDHALAEWLM
260 270 280 290 300
QEEGGDASDP LWRRQVLQQA RTAKEALSAV AETMIVLTPS GRAAREIKLS
310 320 330 340 350
RGRLESLIQP VIQRSLPACR RALRDAGLKL DEIEGVVLVG GATRVPAVRA
360 370 380 390 400
MVEEFFRQKP LTDIDPDQVV AIGAAIQADA LVGNQREDLL LMDVLPLSLG
410 420 430 440 450
LETMGGLVEK IIPRNTPIPV ARAQEFTTFK DGQTAMSIHV VQGERDLVQD
460 470 480 490 500
CRSLARFSLR GIPPMVAGAA RIRVTFQVDA DGLLAVRAEE TSTGVRSEVV
510 520 530 540 550
VKPSYGLNDE EIARMLQDSF IHGAEDVVRR RLSEAKVEGE RVREALRTAL
560 570 580 590 600
AADADLLDPA EREALDKAGT ALTNALSGDD AGVITAAAEA VETAAEPLVQ
610 620
RRMDSALRRA ITGRSIDELG D
Length:621
Mass (Da):66,063
Last modified:October 14, 2008 - v1
Checksum:i8E866632ABE54A01
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001132 Genomic DNA. Translation: ACH83076.1.
RefSeqiWP_012536278.1. NC_011206.1.

Genome annotation databases

EnsemblBacteriaiACH83076; ACH83076; Lferr_0826.
KEGGiafe:Lferr_0826.

Similar proteinsi

Entry informationi

Entry nameiHSCA_ACIF5
AccessioniPrimary (citable) accession number: B5ENY5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 14, 2008
Last modified: June 7, 2017
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families