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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Acidithiobacillus ferrooxidans (strain ATCC 53993) (Leptospirillum ferrooxidans (ATCC 53993))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Acts as a chaperone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaKUniRule annotation
Alternative name(s):
HSP70UniRule annotation
Heat shock 70 kDa proteinUniRule annotation
Heat shock protein 70UniRule annotation
Gene namesi
Name:dnaKUniRule annotation
Ordered Locus Names:Lferr_2291
OrganismiAcidithiobacillus ferrooxidans (strain ATCC 53993) (Leptospirillum ferrooxidans (ATCC 53993))
Taxonomic identifieri380394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAcidithiobacilliaAcidithiobacillalesAcidithiobacillaceaeAcidithiobacillus
Proteomesi
  • UP000001856 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001196571 – 634Chaperone protein DnaKAdd BLAST634

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei199Phosphothreonine; by autocatalysisUniRule annotation1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiB5ENA3

Expressioni

Inductioni

By stress conditions e.g. heat shock.UniRule annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi380394.Lferr_2291

Structurei

3D structure databases

ProteinModelPortaliB5ENA3
SMRiB5ENA3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CFG Bacteria
COG0443 LUCA
HOGENOMiHOG000228136
KOiK04043
OMAiISIKRHM
OrthoDBiPOG091H01UE

Family and domain databases

Gene3Di1.20.1270.10, 1 hit
2.60.34.10, 1 hit
HAMAPiMF_00332 DnaK, 1 hit
InterProiView protein in InterPro
IPR012725 Chaperone_DnaK
IPR018181 Heat_shock_70_CS
IPR029048 HSP70_C_sf
IPR029047 HSP70_peptide-bd_sf
IPR013126 Hsp_70_fam
PANTHERiPTHR19375 PTHR19375, 1 hit
PfamiView protein in Pfam
PF00012 HSP70, 1 hit
PRINTSiPR00301 HEATSHOCK70
SUPFAMiSSF100920 SSF100920, 1 hit
SSF100934 SSF100934, 1 hit
TIGRFAMsiTIGR02350 prok_dnaK, 1 hit
PROSITEiView protein in PROSITE
PS00297 HSP70_1, 1 hit
PS00329 HSP70_2, 1 hit
PS01036 HSP70_3, 1 hit

Sequencei

Sequence statusi: Complete.

B5ENA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKVIGIDLG TTNSCVAVME GDKVKVIENS EGKRTTPSIV AITEEGEVLV
60 70 80 90 100
GEAAKRQAVT NPENTVYEVK RLIGRKFDDA EVQKDLKHVP YKVIKADNGD
110 120 130 140 150
AWVEVRDKKY SAQQISAFIL QKMKKTAEDY LGEKVTEAVI TVPAYFNDAQ
160 170 180 190 200
RQATKDAGRI AGLEVKRIIN EPTAAALAFG EDKKPGDSKI AVYDLGGGTF
210 220 230 240 250
DISIIEIAEM EGEHQFEVLS TNGDTFLGGG DFDSRVINYL ADSFKAESGI
260 270 280 290 300
DLRGDRLAMQ RLKEAAEKAK IELSSAQQTD VNLPFITADQ SGPKHLNMKL
310 320 330 340 350
TRAKLESLVE DLIDRSMAPC RVAMKDANLA TSRITDVILV GGQSRMPKVQ
360 370 380 390 400
EKVKDFFGQD PRKDVNPDEA VAIGAAIQGA VLSGEKKDVL LMDVTPLSLG
410 420 430 440 450
IETLGGVMTK LIEKNTTIPT RKSQIFSTAE DNQSAVTVHV LQGERELARD
460 470 480 490 500
NKSLARFDLT DIANAPRGMP QIEVTFDIDA NGILHVSAKD NQTGKEQSIK
510 520 530 540 550
ITASSGLSEE EIKRMIQEAE AHAADDKKAR ALIEARNEAD ASVHGARKAV
560 570 580 590 600
EEHAAAPEHD KTKVTEAISA VENAAKGEDV EAIKGAVATL MAAMSALLQS
610 620 630
AAAGQAQAES GAGAQGNAKP DDVVDAEFEE VDKK
Length:634
Mass (Da):68,222
Last modified:October 14, 2008 - v1
Checksum:i888BB47971ADD4C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001132 Genomic DNA Translation: ACH84492.1
RefSeqiWP_009563301.1, NC_011206.1

Genome annotation databases

EnsemblBacteriaiACH84492; ACH84492; Lferr_2291
KEGGiafe:Lferr_2291

Similar proteinsi

Entry informationi

Entry nameiDNAK_ACIF5
AccessioniPrimary (citable) accession number: B5ENA3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 14, 2008
Last modified: February 28, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health