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B5EN79 (B5EN79_ACIF5) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonucleoside-diphosphate reductase subunit beta PIRNR PIRNR000355
EC=1.17.4.1 PIRNR PIRNR000355
Gene names
Ordered Locus Names:Lferr_2265
OrganismAcidithiobacillus ferrooxidans (strain ATCC 53993) (Leptospirillum ferrooxidans (ATCC 53993)) [Complete proteome] [HAMAP] EMBL ACH84468.1
Taxonomic identifier380394 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Acidithiobacillales › Acidithiobacillaceae › Acidithiobacillus ›

Protein attributes

Sequence length374 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides By similarity. PIRNR PIRNR000355

Catalytic activity

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. PIRNR PIRNR000355

Cofactor

Binds 2 iron ions per subunit By similarity. PIRNR PIRNR000355

Pathway

Genetic information processing; DNA replication. PIRNR PIRNR000355

Sequence similarities

Belongs to the ribonucleoside diphosphate reductase small chain family. PIRNR PIRNR000355

Sequences

Sequence LengthMass (Da)Tools
B5EN79 [UniParc].

Last modified October 14, 2008. Version 1.
Checksum: 3D698B1AFA042C0F

FASTA37443,331
        10         20         30         40         50         60 
MLSFEENLRK ESILNGPLAT RPEHVGGIEE TGMTSFERVR AEDKRIINGH ADVNQLVPFK 

        70         80         90        100        110        120 
YQWAWDKYLA ACANHWMPQE IQMSRDIALW KDPKGLTEDE RRIVKRNLGF FVTADSLAAN 

       130        140        150        160        170        180 
NIVLGTYRHI TAPECRQYML RQAFEEAIHT HAYQYIVESI GLDEGEIFNM YHEVPSVRDK 

       190        200        210        220        230        240 
DQFLMPFIDV LADPHFKTGT LENDQKLLRS LIVFAAIMEG TFFYVGFSQI LAMGRQNKMV 

       250        260        270        280        290        300 
GAAEQYQYIL RDESMHCNFG IDMANQIKVE NPQLWTEAFQ QEIIDLIRRG VELECAYADD 

       310        320        330        340        350        360 
TMPRGVLGLN APVFREYVKY IGNRRLVQLG LPQQYPGVQN PFPWMSEMMD LKKEKNFFET 

       370 
RVTEYQTGGA LSWE

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References

[1]"Complete sequence of Acidithiobacillus ferrooxidans ATCC 53993."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Kuske C.R., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Borole A.P.
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 53993.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001132 Genomic DNA. Translation: ACH84468.1.
RefSeqYP_002220675.1. NC_011206.1.

3D structure databases

ProteinModelPortalB5EN79.
ModBaseSearch...

Protein-protein interaction databases

STRING380394.Lferr_2265.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACH84468; ACH84468; Lferr_2265.
GeneID6878259.
KEGGafe:Lferr_2265.
PATRIC20662136. VBIAciFer6930_2254.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0208.
HOGENOMHOG000255976.
KOK00526.
OMAICNRRCQ.
ProtClustDBPRK07209.

Enzyme and pathway databases

BioCycAFER380394:GHE0-2310-MONOMER.
UniPathwayUPA00326.

Family and domain databases

Gene3D1.10.620.20. 1 hit.
InterProIPR009078. Ferritin-like_SF.
IPR012348. RNR-rel.
IPR026023. RNR_bsu_prok.
IPR000358. RNR_small.
[Graphical view]
PANTHERPTHR23409. PTHR23409. 1 hit.
PfamPF00268. Ribonuc_red_sm. 1 hit.
[Graphical view]
PIRSFPIRSF000355. NrdB. 1 hit.
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB5EN79_ACIF5
AccessionPrimary (citable) accession number: B5EN79
Entry history
Integrated into UniProtKB/TrEMBL: October 14, 2008
Last sequence update: October 14, 2008
Last modified: May 1, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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