Reviewed, UniProtKB/Swiss-Prot B5EJT1 (AROC_ACIF5)

Names and origin

Protein names

Recommended name:
    Chorismate synthase
    EC=4.2.3.5
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	Lferr_1640

Organism

Acidithiobacillus ferrooxidans (strain ATCC 53993) (Leptospirillum ferrooxidans (ATCC 53993)) [Complete proteome] [HAMAP]

Taxonomic identifier

380394 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Acidithiobacillales › Acidithiobacillaceae › Acidithiobacillus

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity.
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 363	363	Chorismate synthase HAMAP MF_00300		PRO_1000115321

Sequences

	Sequence		Length	Mass (Da)
	B5EJT1-1 [UniParc]. Last modified October 14, 2008. Version 1. Checksum: A8049DA2B3E73F01	FASTA	363	38,913
	10 20 30 40 50 60 MAGSSIGECF RVSTFGESHG PAIGCIVDGC PPGMTLSAAD IQTELDRRRP GRSRHTTQRQ 70 80 90 100 110 120 EADQVEILSG VFEGLTTGTP IGLLIRNTDQ RSQDYSKIKD LFRPGHADYT YLQKYGLRDY 130 140 150 160 170 180 RGGGRSSARE TAMRVAAGAI ARKFLRERLG VNIQAWMAQM GPIHAEDFDA AEISHNDFFC 190 200 210 220 230 240 PDAGAAIRMA DFLDGLRKEG DSIGARVDAR VSGMPVGLGE PVFDRLEADI AKAMMSINAV 250 260 270 280 290 300 KAIAVGDGFA VVEQRGSYHG DAMAATGFQS NHAGGVLGGI SSGQDLTLSV AIKPTSSIRI 310 320 330 340 350 360 PRQSIDVHGR PAEVITTGRH DPCVGIRAVP IVEAMLALVI MDHWMRHRAQ NADVQAPLPP IPA

References

[1]

"Complete sequence of Acidithiobacillus ferrooxidans ATCC 53993." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Kuske C.R., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Borole A.P. Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP001132 Genomic DNA. Translation: ACH83862.1.
RefSeq	YP_002220069.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	6877620.
GenomeReviews	Gene locus Lferr_1640 in contig CP001132_GR.
KEGG	afe:Lferr_1640.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	SRFTTQR.
Family and domain databases
HAMAP	MF_00300. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
TIGRFAMs	TIGR00033. aroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_ACIF5

Accession

Primary (citable) accession number: B5EJT1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	October 14, 2008
Last modified:	November 3, 2009
This is version 8 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)