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Protein

Chaperone protein ClpB

Gene

clpB

Organism
Acidithiobacillus ferrooxidans (strain ATCC 53993) (Leptospirillum ferrooxidans (ATCC 53993))
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotationSAAS annotation
Biological processStress responseUniRule annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein ClpBUniRule annotation
Gene namesi
Name:clpBUniRule annotation
Ordered Locus Names:Lferr_1638Imported
OrganismiAcidithiobacillus ferrooxidans (strain ATCC 53993) (Leptospirillum ferrooxidans (ATCC 53993))Imported
Taxonomic identifieri380394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAcidithiobacilliaAcidithiobacillalesAcidithiobacillaceaeAcidithiobacillus
Proteomesi
  • UP000001856 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homohexamer. The oligomerization is ATP-dependent.SAAS annotation
Homohexamer; The oligomerization is ATP-dependent.UniRule annotation

Protein-protein interaction databases

STRINGi380394.Lferr_1638

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini198 – 343AAAInterPro annotationAdd BLAST146
Domaini602 – 757AAAInterPro annotationAdd BLAST156
Domaini771 – 860ClpB_D2-smallInterPro annotationAdd BLAST90

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili405 – 439UniRule annotationAdd BLAST35

Sequence similaritiesi

Belongs to the ClpA/ClpB family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilUniRule annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C2Z Bacteria
COG0542 LUCA
HOGENOMiHOG000218209
KOiK03695
OMAiHHKVRIK
OrthoDBiPOG091H019M

Family and domain databases

Gene3Di1.10.1780.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR017730 Chaperonin_ClpB
IPR019489 Clp_ATPase_C
IPR004176 Clp_N
IPR036628 Clp_N_dom_sf
IPR001270 ClpA/B
IPR018368 ClpA/B_CS1
IPR028299 ClpA/B_CS2
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00004 AAA, 1 hit
PF07724 AAA_2, 1 hit
PF02861 Clp_N, 2 hits
PF10431 ClpB_D2-small, 1 hit
PRINTSiPR00300 CLPPROTEASEA
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SM01086 ClpB_D2-small, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
SSF81923 SSF81923, 1 hit
TIGRFAMsiTIGR03346 chaperone_ClpB, 1 hit
PROSITEiView protein in PROSITE
PS00870 CLPAB_1, 1 hit
PS00871 CLPAB_2, 1 hit

Sequencei

Sequence statusi: Complete.

B5EJS9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTDKLTTKF QQAFQDAQSL ALAQDHQQME PIHLLAAFLD QEGGIARPLL
60 70 80 90 100
SKAGVRVDAL RNQLNRALES MPKVQGHPGE VQVGRDLTNM LNLADKIGQK
110 120 130 140 150
RGDTYISTEH FLLALMDDKG EAGRLLKEAG ATTKDLEQAV HDLHGGEKIN
160 170 180 190 200
DANAEEQRQA LEKYTIDYTE RASQGKLDPV IGRDDEIRRT IQVLLRRSKN
210 220 230 240 250
NPVLIGEPGV GKTAIVEGLA LRLINGEVPE SLRDKRLLGL DLGALIAGAK
260 270 280 290 300
FRGEFEERLK SLLNDLEKSE GKIILFIDEI HTLVGAGKAE GSMDAGNMLK
310 320 330 340 350
PALARGELHC IGATTLDEYR KYIEKDAALE RRFQRVLVDE PSVEDAIAIL
360 370 380 390 400
RGLKERYEAH HGVRITDPAL VAAVQLSHRY ITDRNLPDKA IDLMDEAASR
410 420 430 440 450
IKMEIDSKPQ ELDELERRII QLNIERVALE KEKDEASRKR LDILQAQIKE
460 470 480 490 500
SDRKYQELEE VWKGEKLAIE GTSQIQKELD RKRVELDTAR RANDLERMAE
510 520 530 540 550
LQYSSIPALE AQLHAAEIHA QSAGSGAKPT LLRTEVGEEE IAEVVARWTG
560 570 580 590 600
IPVSKMLEGE KEKLLKMEER LQARVVGQSE AVAAVSNAIR RSRAGLSDPK
610 620 630 640 650
RPNGSFLFLG PTGVGKTELT KALAEFLFDS EDHLVRIDMS EFMEKHSVAR
660 670 680 690 700
LIGAPPGYVG YEEGGYLTEA VRRKPYSVVL LDEVEKAHPE VFNILLQVLD
710 720 730 740 750
DGRLTDGQGR TVDFRNTVIV MTSNLGSDRI QEFSRKGEYD SMRVAVLDVV
760 770 780 790 800
QDHFRPEFLN RIDELVIFRP LTAVQLREIT GIQMGFLRSR LRERDMDLVL
810 820 830 840 850
SDGALDHLAE VGYDPVYGAR PLKRVIQREI ENPLAQKLLR GDFGPGEIIE
860
VVLEGDRFTF VGQRVH
Length:866
Mass (Da):97,058
Last modified:October 14, 2008 - v1
Checksum:i6487F0D147D1D7C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001132 Genomic DNA Translation: ACH83860.1
RefSeqiWP_012536875.1, NC_011206.1

Genome annotation databases

EnsemblBacteriaiACH83860; ACH83860; Lferr_1638
KEGGiafe:Lferr_1638

Similar proteinsi

Entry informationi

Entry nameiB5EJS9_ACIF5
AccessioniPrimary (citable) accession number: B5EJS9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 14, 2008
Last sequence update: October 14, 2008
Last modified: March 28, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health