Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Acidithiobacillus ferrooxidans (strain ATCC 53993) (Leptospirillum ferrooxidans (ATCC 53993))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei146 – 1461UniRule annotation
Active sitei586 – 5861UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciAFER380394:GHE0-1584-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Lferr_1558Imported
OrganismiAcidithiobacillus ferrooxidans (strain ATCC 53993) (Leptospirillum ferrooxidans (ATCC 53993))Imported
Taxonomic identifieri380394 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAcidithiobacillalesAcidithiobacillaceaeAcidithiobacillus
ProteomesiUP000001856 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi380394.Lferr_1558.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5EJA6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKKALNGKA LRNRVKLLGN LLGEVLREQA GHRVFNAVEQ LRQGYIRLHK
60 70 80 90 100
REDLRLRERL ARFIDALPQD DLVLVIRAFN TYFSLVNIAE EEFQHLHRRR
110 120 130 140 150
LLQKGSMLWT GSFEETFREL QGQGINPGQL QFLLDQIRYL PVFTAHPTES
160 170 180 190 200
KRRTVLHALR RIFVTSKMLD DSALNDEEEQ EVMDNLRAQI QILWETEEVR
210 220 230 240 250
TNKPQVQDEV ENGLFYFRDS LFEAVPLTYR AARRAARRVF ANADIDIPAF
260 270 280 290 300
IRFGSWIGGD RDGNPNVTAA ITGWALRTQS IEVLKEYQQR LSDLYQLLGH
310 320 330 340 350
SSRFCAISPV LLASLERDAD DFPELAEWVD QRFPSEPYRR KLRYMMTRLD
360 370 380 390 400
LRLRQLENGQ VLNESAGPAY AAAEDFLDDL LLVRDSLRGH NDGYIADNEV
410 420 430 440 450
QEIIWLVQTF GFHLANLDIR QESSVHSRTI AELFAGIPGF ANYVELSEEA
460 470 480 490 500
RMLALSDALR RPGPLVEQAP DLSPMAAETC AMFRCIAQLR REVSTAGFGN
510 520 530 540 550
YVISMTHEAS HIMEVLVLAK EFGLAGWSRQ GLYSEIAVTP LFETIHDLER
560 570 580 590 600
MDTVMSTLLD NPVYAKILGS QDDIQEVMLG YSDSCKDGGI LSSSWSLYQA
610 620 630 640 650
QLRLAALADK RKIRIRVFHG RGGSVGRGGG PTYEAILAQP PDTVRGQIKI
660 670 680 690 700
TEQGEVLSFK YANLETAVYE LTVGTAGLIK ASIGLVRSAS GDNPDHLKIM
710 720 730 740 750
AELTRTGEAV YRDLTEGTPG FMDYFYEATP LNEIAHMNIG SRPSHRQRGD
760 770 780 790 800
RSMSSIRAIP WIFAWAQSRH VLPAWYGLGS ALARWREDKP ERLQALQDMY
810 820 830 840 850
RHWPFFRALM GNIGMAMAKT DMAIAGEYAG LPNDRDAAIA IYRKIQAEFE
860 870 880 890 900
SSQAEMLAIV GADHLLADNP TLAFSLQRRN VYMEPLNHIQ LALLRRYRND
910 920
ETPPEFREIW LDPLLRTINA ISAGQRNTG
Length:929
Mass (Da):105,418
Last modified:October 14, 2008 - v1
Checksum:iF8443F969083CBD8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001132 Genomic DNA. Translation: ACH83780.1.
RefSeqiWP_012536819.1. NC_011206.1.
YP_002219987.1. NC_011206.1.

Genome annotation databases

EnsemblBacteriaiACH83780; ACH83780; Lferr_1558.
KEGGiafe:Lferr_1558.
PATRICi20660724. VBIAciFer6930_1565.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001132 Genomic DNA. Translation: ACH83780.1.
RefSeqiWP_012536819.1. NC_011206.1.
YP_002219987.1. NC_011206.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi380394.Lferr_1558.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACH83780; ACH83780; Lferr_1558.
KEGGiafe:Lferr_1558.
PATRICi20660724. VBIAciFer6930_1565.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciAFER380394:GHE0-1584-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Acidithiobacillus ferrooxidans ATCC 53993."
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Kuske C.R., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Borole A.P.
    Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 53993Imported.

Entry informationi

Entry nameiB5EJA6_ACIF5
AccessioniPrimary (citable) accession number: B5EJA6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 14, 2008
Last sequence update: October 14, 2008
Last modified: June 24, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.