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B5EJ55 (B5EJ55_GEOBB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
L-threonine 3-dehydrogenase HAMAP MF_00627
EC=1.1.1.103 HAMAP MF_00627
Gene names
Name:tdh HAMAP MF_00627
Ordered Locus Names:Gbem_0050
OrganismGeobacter bemidjiensis (strain Bem / ATCC BAA-1014 / DSM 16622) [Complete proteome] [HAMAP]
Taxonomic identifier404380 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter

Protein attributes

Sequence length347 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-threonine + NAD+ = L-2-amino-3-oxobutanoate + NADH. HAMAP MF_00627 SAAS SAAS002328

Cofactor

Binds 2 zinc ions per subunit By similarity. HAMAP MF_00627 SAAS SAAS002328

Pathway

Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 1/2. HAMAP MF_00627 SAAS SAAS002328

Subunit structure

Homotetramer By similarity. HAMAP MF_00627

Subcellular location

Cytoplasm By similarity HAMAP MF_00627 SAAS SAAS002328.

Sequence similarities

Belongs to the zinc-containing alcohol dehydrogenase family. HAMAP MF_00627 RuleBase RU000468

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding421Zinc 1; catalytic By similarity HAMAP MF_00627
Metal binding671Zinc 1; catalytic By similarity HAMAP MF_00627
Metal binding971Zinc 2 By similarity HAMAP MF_00627
Metal binding1001Zinc 2 By similarity HAMAP MF_00627
Metal binding1031Zinc 2 By similarity HAMAP MF_00627
Metal binding1111Zinc 2 By similarity HAMAP MF_00627
Metal binding1521Zinc 1; catalytic By similarity HAMAP MF_00627

Sequences

Sequence LengthMass (Da)Tools
B5EJ55 [UniParc].

Last modified October 14, 2008. Version 1.
Checksum: 20D4F6019DE00C2F

FASTA34738,091
        10         20         30         40         50         60 
MQKTMQALVK KYPKPGLWLD EVPVPEVGIN DVLIKVHKTA VCGTDLHIWD WNDWARKTIP 

        70         80         90        100        110        120 
VPMVVGHEFV GRVAAMGSNV ADLNIGDIVS GEGHIVCGRC RNCLAGRRHL CKDTNGVGVN 

       130        140        150        160        170        180 
RAGAFAEYIC IPVTNVWHAD PTIPMEILGI FDPFGNATHT TLAFPILGED VLITGAGPIG 

       190        200        210        220        230        240 
IMATAIARHA GARYIVVTDL NQYRLDLAKK MGATVALNVR EGTLAQVRQQ LGMKEGFDVG 

       250        260        270        280        290        300 
LEMSGNGDAF KEMLANMCHG GKIAMLGLPS GDLAVDWNQV IFNMLTIKGI YGREMYETWY 

       310        320        330        340 
LMQSLIKIGL DLTPVITHRM HYTEFEEAFR VMSTGNAGKV MLNWVEE

« Hide

References

[1]"Complete sequence of Geobacter bemidjiensis BEM."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Lykidis A., Lovley D., Richardson P.
Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bem / ATCC BAA-1014 / DSM 16622.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001124 Genomic DNA. Translation: ACH37081.1.
RefSeqYP_002136877.1. NC_011146.1.

3D structure databases

ProteinModelPortalB5EJ55.
ModBaseSearch...

Protein-protein interaction databases

STRINGB5EJ55.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6782868.
GenomeReviewsGene locus Gbem_0050 in contig CP001124_GR.
KEGGgbm:Gbem_0050.
PATRIC21983755. VBIGeoBem56306_0049.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG753318.
OMAGRCRNCL.
ProtClustDBPRK05396.

Family and domain databases

HAMAPMF_00627. Thr_dehydrog.
[Tree]
InterProIPR013149. ADH_C.
IPR013154. ADH_GroES-like.
IPR002085. ADH_SF_Zn-type.
IPR002328. ADH_Zn_CS.
IPR011032. GroES-like.
IPR004627. L-Threonine_3-DHase.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00060.
PANTHERPTHR11695. ADH_Sf_Zn. 1 hit.
PfamPF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
[Graphical view]
SUPFAMSSF50129. GroES_like. 1 hit.
TIGRFAMsTIGR00692. Tdh. 1 hit.
PROSITEPS00059. ADH_ZINC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB5EJ55_GEOBB
AccessionPrimary (citable) accession number: B5EJ55
Entry history
Integrated into UniProtKB/TrEMBL: October 14, 2008
Last sequence update: October 14, 2008
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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