Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B5EI63

- PNP_GEOBB

UniProt

B5EI63 - PNP_GEOBB

Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Geobacter bemidjiensis (strain Bem / ATCC BAA-1014 / DSM 16622)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (14 Oct 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

    Catalytic activityi

    RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi483 – 4831MagnesiumUniRule annotation
    Metal bindingi489 – 4891MagnesiumUniRule annotation

    GO - Molecular functioni

    1. 3'-5'-exoribonuclease activity Source: InterPro
    2. magnesium ion binding Source: UniProtKB-HAMAP
    3. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP
    4. RNA binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. mRNA catabolic process Source: UniProtKB-HAMAP
    2. RNA processing Source: InterPro

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Ligandi

    Magnesium, Metal-binding, RNA-binding

    Enzyme and pathway databases

    BioCyciGBEM404380:GHFR-1344-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
    Alternative name(s):
    Polynucleotide phosphorylaseUniRule annotation
    Short name:
    PNPaseUniRule annotation
    Gene namesi
    Name:pnpUniRule annotation
    Ordered Locus Names:Gbem_1308
    OrganismiGeobacter bemidjiensis (strain Bem / ATCC BAA-1014 / DSM 16622)
    Taxonomic identifieri404380 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
    ProteomesiUP000008825: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 696696Polyribonucleotide nucleotidyltransferasePRO_0000381898Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi404380.Gbem_1308.

    Structurei

    3D structure databases

    ProteinModelPortaliB5EI63.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini550 – 60960KHUniRule annotationAdd
    BLAST
    Domaini619 – 68769S1 motifUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation
    Contains 1 KH domain.UniRule annotation
    Contains 1 S1 motif domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1185.
    HOGENOMiHOG000218327.
    KOiK00962.
    OMAiHGNFKSN.
    OrthoDBiEOG6WT8CC.

    Family and domain databases

    Gene3Di1.10.10.400. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1370.10. 1 hit.
    3.30.230.70. 2 hits.
    HAMAPiMF_01595. PNPase.
    InterProiIPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR004087. KH_dom.
    IPR004088. KH_dom_type_1.
    IPR012340. NA-bd_OB-fold.
    IPR012162. PNPase.
    IPR027408. PNPase/RNase_PH_dom.
    IPR015848. PNPase_PH_RNA-bd_bac/org-type.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR022967. RNA-binding_domain_S1.
    [Graphical view]
    PANTHERiPTHR11252. PTHR11252. 1 hit.
    PfamiPF00013. KH_1. 1 hit.
    PF03726. PNPase. 1 hit.
    PF01138. RNase_PH. 2 hits.
    PF03725. RNase_PH_C. 2 hits.
    PF00575. S1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005499. PNPase. 1 hit.
    SMARTiSM00322. KH. 1 hit.
    SM00316. S1. 1 hit.
    [Graphical view]
    SUPFAMiSSF46915. SSF46915. 1 hit.
    SSF50249. SSF50249. 1 hit.
    SSF54211. SSF54211. 2 hits.
    SSF54791. SSF54791. 1 hit.
    SSF55666. SSF55666. 2 hits.
    TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
    PROSITEiPS50084. KH_TYPE_1. 1 hit.
    PS50126. S1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B5EI63-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVHTVQAECC GKTITIETGK IAKQASGAVM IKSGDTMVLV TAVAMKSAKE    50
    GQGFFPLTVN YQEKAYAGGR IPGSFFKREG RPSDNETLTC RLIDRPIRPL 100
    FPENFLNDTQ IMATVVSADK DNDPGILSMI GASAALMVSD VPFAGPIAGV 150
    KVGRVDGQFI ANPTAEQEEK SDLEIVIAAS QDAILMVEGS ACEVSEDDLL 200
    EAIFFGHKAV QPVLAAQLEL AKKVGTSKRE IPAPVVNEAL KARVSALAKE 250
    GMKQAVRIKT KVERHLAIDA IADETVAALS AEFEGSEKEI KGFIEDLEYD 300
    LVREHIIKDG QRIDGRDTKT IRAISTEVSL LPRAHGSALF TRGETQSIVA 350
    ATLGTSVDEQ RIDSLYGDSR KKFMLHYNFP PYSVGETSFR LAPGRREIGH 400
    GMLAERALQQ VLPKHDDFPY TIRIVSDITE SNGSSSMATV CGGSLSMMDA 450
    GIPIKAPVAG IAMGLIKEGD DFAILSDILG DEDHLGDMDF KVAGTAEGVT 500
    ALQMDIKIGG VTREIMSAAL AQAKAGRIHI LGEMAKTIGA SRGDLSAFAP 550
    RITTIWVKVD KIRDVIGSGG KNIRSVTEAT GVSIDIDDTG KINIASTNKE 600
    ACDLAIKMIR NLTAEAEEGK LYMGTVKKIM EFGAFVEIFP GTDGLVHVSE 650
    LDTERVKNVS DILKEGDKVL VKCIGIDKQG KIKLSRKEAL GLTFTE 696
    Length:696
    Mass (Da):74,701
    Last modified:October 14, 2008 - v1
    Checksum:i14A55B42966E28D8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001124 Genomic DNA. Translation: ACH38327.1.
    RefSeqiYP_002138123.1. NC_011146.1.

    Genome annotation databases

    EnsemblBacteriaiACH38327; ACH38327; Gbem_1308.
    GeneIDi6781295.
    KEGGigbm:Gbem_1308.
    PATRICi21986342. VBIGeoBem56306_1299.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001124 Genomic DNA. Translation: ACH38327.1 .
    RefSeqi YP_002138123.1. NC_011146.1.

    3D structure databases

    ProteinModelPortali B5EI63.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 404380.Gbem_1308.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACH38327 ; ACH38327 ; Gbem_1308 .
    GeneIDi 6781295.
    KEGGi gbm:Gbem_1308.
    PATRICi 21986342. VBIGeoBem56306_1299.

    Phylogenomic databases

    eggNOGi COG1185.
    HOGENOMi HOG000218327.
    KOi K00962.
    OMAi HGNFKSN.
    OrthoDBi EOG6WT8CC.

    Enzyme and pathway databases

    BioCyci GBEM404380:GHFR-1344-MONOMER.

    Family and domain databases

    Gene3Di 1.10.10.400. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1370.10. 1 hit.
    3.30.230.70. 2 hits.
    HAMAPi MF_01595. PNPase.
    InterProi IPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR004087. KH_dom.
    IPR004088. KH_dom_type_1.
    IPR012340. NA-bd_OB-fold.
    IPR012162. PNPase.
    IPR027408. PNPase/RNase_PH_dom.
    IPR015848. PNPase_PH_RNA-bd_bac/org-type.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR022967. RNA-binding_domain_S1.
    [Graphical view ]
    PANTHERi PTHR11252. PTHR11252. 1 hit.
    Pfami PF00013. KH_1. 1 hit.
    PF03726. PNPase. 1 hit.
    PF01138. RNase_PH. 2 hits.
    PF03725. RNase_PH_C. 2 hits.
    PF00575. S1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005499. PNPase. 1 hit.
    SMARTi SM00322. KH. 1 hit.
    SM00316. S1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46915. SSF46915. 1 hit.
    SSF50249. SSF50249. 1 hit.
    SSF54211. SSF54211. 2 hits.
    SSF54791. SSF54791. 1 hit.
    SSF55666. SSF55666. 2 hits.
    TIGRFAMsi TIGR03591. polynuc_phos. 1 hit.
    PROSITEi PS50084. KH_TYPE_1. 1 hit.
    PS50126. S1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bem / ATCC BAA-1014 / DSM 16622.

    Entry informationi

    Entry nameiPNP_GEOBB
    AccessioniPrimary (citable) accession number: B5EI63
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 1, 2009
    Last sequence update: October 14, 2008
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3