B5EH01 (B5EH01_GEOBB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
NH(3)-dependent NAD(+) synthetase RuleBase RU003812
EC=6.3.1.5 RuleBase RU003812

Gene names

Name:	nadE-2 EMBL ACH38103.1
Ordered Locus Names:	Gbem_1083

Organism

Geobacter bemidjiensis (strain Bem / ATCC BAA-1014 / DSM 16622) [Complete proteome] [HAMAP]

Taxonomic identifier

404380 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter

Protein attributes

Sequence length	328 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+. RuleBase RU003812 SAAS SAAS003694
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (ammonia route): step 1/1. SAAS SAAS003694 RuleBase RU004252
Sequence similarities	Belongs to the NAD synthetase family. RuleBase RU003811

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS003694 RuleBase RU003811 NAD SAAS SAAS003694 RuleBase RU003811 Nucleotide-binding
Molecular function	Ligase SAAS SAAS003694 RuleBase RU003811
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ synthase (glutamine-hydrolyzing) activity Inferred from electronic annotation. Source: InterPro NAD+ synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B5EH01 [UniParc]. Last modified October 14, 2008. Version 1. Checksum: 7DF3C99B9BDDCBFE	FASTA	328	36,564
	10 20 30 40 50 60 MNGGIFSKEV LRLDPEREVE RICARVKELM LTQVKRRGLV VALSGGIDSS VTAALAVRAI 70 80 90 100 110 120 GKERVIGLEM PERHSSGESQ KLSGKLAAAL GIETVLEEIS AALEAVGCYR KYDEAVRMVV 130 140 150 160 170 180 PGYGEGWKSK IVISNNMEHP GFTSFYLVAQ DGAQGTTRVR LPFKPYLQIV AATNFKQRIR 190 200 210 220 230 240 KMLEYYHADR LNFAVAGTPN RLEYDQGFFV KLGDGAADIK PIAHLYKSQV YQLAEYLGVP 250 260 270 280 290 300 EEIRRRTPTT DTYSLAQGQD EFYFSLPYPE MDLCLFAKNN GVAPESVAAA LGLTPEQVRL 310 320 VFQDIEVKRS STRYLHLPPL LVEAVDWQ

References

[1]

"Complete sequence of Geobacter bemidjiensis BEM." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Lykidis A., Lovley D., Richardson P. Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bem / ATCC BAA-1014 / DSM 16622.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001124 Genomic DNA. Translation: ACH38103.1.
RefSeq	YP_002137899.1. NC_011146.1.
3D structure databases
ProteinModelPortal	B5EH01.
ModBase	Search...
Protein-protein interaction databases
STRING	B5EH01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6781061.
GenomeReviews	Gene locus Gbem_1083 in contig CP001124_GR.
KEGG	gbm:Gbem_1083.
PATRIC	21985892. VBIGeoBem56306_1083.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG351567.
OMA	AHLYKSQ.
ProtClustDB	PRK00876.
Family and domain databases
HAMAP	MF_00193. NadE. [Tree]
InterPro	IPR022310. NAD/GMP_synthase. IPR003694. NAD_synthase. IPR022926. NH(3)-dep_NAD(+)_synth. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K01916.
Pfam	PF02540. NAD_synthase. 2 hits. [Graphical view]
TIGRFAMs	TIGR00552. NadE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B5EH01_GEOBB

Accession

Primary (citable) accession number: B5EH01

Entry history

Integrated into UniProtKB/TrEMBL:	October 14, 2008
Last sequence update:	October 14, 2008
Last modified:	December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)