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Protein

Cobalt-precorrin-5B C(1)-methyltransferase

Gene

cbiD

Organism
Geobacter bemidjiensis (strain Bem / ATCC BAA-1014 / DSM 16622)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.UniRule annotation

Catalytic activityi

Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.UniRule annotation

Pathwayi: adenosylcobalamin biosynthesis

This protein is involved in step 6 of the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route).UniRule annotation
Proteins known to be involved in the 10 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
  6. Cobalt-precorrin-5B C(1)-methyltransferase (cbiD)
  7. no protein annotated in this organism
  8. no protein annotated in this organism
  9. no protein annotated in this organism
  10. Cobyrinate a,c-diamide synthase (cbiA)
This subpathway is part of the pathway adenosylcobalamin biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route), the pathway adenosylcobalamin biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

Cobalamin biosynthesis

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciGBEM404380:GHFR-3611-MONOMER.
UniPathwayiUPA00148; UER00227.

Names & Taxonomyi

Protein namesi
Recommended name:
Cobalt-precorrin-5B C(1)-methyltransferaseUniRule annotation (EC:2.1.1.195UniRule annotation)
Alternative name(s):
Cobalt-precorrin-6A synthaseUniRule annotation
Gene namesi
Name:cbiDUniRule annotation
Ordered Locus Names:Gbem_3544
OrganismiGeobacter bemidjiensis (strain Bem / ATCC BAA-1014 / DSM 16622)
Taxonomic identifieri404380 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
Proteomesi
  • UP000008825 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 356356Cobalt-precorrin-5B C(1)-methyltransferasePRO_1000133737Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi404380.Gbem_3544.

Family & Domainsi

Sequence similaritiesi

Belongs to the CbiD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EE8. Bacteria.
COG1903. LUCA.
HOGENOMiHOG000009126.
KOiK02188.
OMAiMMVHSKS.
OrthoDBiEOG6WX4M7.

Family and domain databases

HAMAPiMF_00787. CbiD.
InterProiIPR002748. CbiD.
[Graphical view]
PfamiPF01888. CbiD. 1 hit.
[Graphical view]
PIRSFiPIRSF026782. CbiD. 1 hit.
SUPFAMiSSF111342. SSF111342. 1 hit.
TIGRFAMsiTIGR00312. cbiD. 1 hit.

Sequencei

Sequence statusi: Complete.

B5EC81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGKELRYGF TTGACAAAAV KAAAQMLRDQ GMVHEVELML PCGIGASFQV
60 70 80 90 100
HGGVLRDNTA SCYVVKDAGD DPDVTNGAEI HVTASIEFFT KNRIVIEGGT
110 120 130 140 150
GIGRVTKPGL AVPVGEWAIN PVPRSMILEV VKEVFALRCI PATLTFNISI
160 170 180 190 200
PNGEELAKKT LNERLGIVGG LSILGTTGIV KPISAKAWTD TVDASVDVAL
210 220 230 240 250
ACGARTVVLA TGRSSEIVAQ KHLALSEEAF VMMGDHFGYA MRSCASKEVP
260 270 280 290 300
EVVVAGQFAK LVKIACGHEQ THVTSSQMDL DALAWWLREV PATAHLEQMA
310 320 330 340 350
REANTARHLL EASGYNQAVI ELVCSRVLKV CAEVAPWVKM RVMLAGYHGE

LLYFTP
Length:356
Mass (Da):38,031
Last modified:October 14, 2008 - v1
Checksum:iDC66983C0B8B7324
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001124 Genomic DNA. Translation: ACH40537.1.
RefSeqiWP_012531973.1. NC_011146.1.

Genome annotation databases

EnsemblBacteriaiACH40537; ACH40537; Gbem_3544.
KEGGigbm:Gbem_3544.
PATRICi21990710. VBIGeoBem56306_3457.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001124 Genomic DNA. Translation: ACH40537.1.
RefSeqiWP_012531973.1. NC_011146.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi404380.Gbem_3544.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACH40537; ACH40537; Gbem_3544.
KEGGigbm:Gbem_3544.
PATRICi21990710. VBIGeoBem56306_3457.

Phylogenomic databases

eggNOGiENOG4105EE8. Bacteria.
COG1903. LUCA.
HOGENOMiHOG000009126.
KOiK02188.
OMAiMMVHSKS.
OrthoDBiEOG6WX4M7.

Enzyme and pathway databases

UniPathwayiUPA00148; UER00227.
BioCyciGBEM404380:GHFR-3611-MONOMER.

Family and domain databases

HAMAPiMF_00787. CbiD.
InterProiIPR002748. CbiD.
[Graphical view]
PfamiPF01888. CbiD. 1 hit.
[Graphical view]
PIRSFiPIRSF026782. CbiD. 1 hit.
SUPFAMiSSF111342. SSF111342. 1 hit.
TIGRFAMsiTIGR00312. cbiD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bem / ATCC BAA-1014 / DSM 16622.

Entry informationi

Entry nameiCBID_GEOBB
AccessioniPrimary (citable) accession number: B5EC81
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 14, 2008
Last modified: November 11, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.