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Protein

C4-dicarboxylate transport protein

Gene

dctA

Organism
Geobacter bemidjiensis (strain Bem / ATCC BAA-1014 / DSM 16622)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Symport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
C4-dicarboxylate transport proteinUniRule annotation
Gene namesi
Name:dctAUniRule annotation
Ordered Locus Names:Gbem_3225
OrganismiGeobacter bemidjiensis (strain Bem / ATCC BAA-1014 / DSM 16622)
Taxonomic identifieri404380 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
Proteomesi
  • UP000008825 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei9 – 29HelicalUniRule annotationAdd BLAST21
Transmembranei45 – 65HelicalUniRule annotationAdd BLAST21
Transmembranei80 – 100HelicalUniRule annotationAdd BLAST21
Transmembranei150 – 170HelicalUniRule annotationAdd BLAST21
Transmembranei186 – 206HelicalUniRule annotationAdd BLAST21
Transmembranei221 – 241HelicalUniRule annotationAdd BLAST21
Transmembranei291 – 311HelicalUniRule annotationAdd BLAST21
Transmembranei334 – 354HelicalUniRule annotationAdd BLAST21
Transmembranei357 – 377HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001652891 – 439C4-dicarboxylate transport proteinAdd BLAST439

Interactioni

Protein-protein interaction databases

STRINGi404380.Gbem_3225.

Structurei

3D structure databases

ProteinModelPortaliB5E9Q0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CK2. Bacteria.
COG1301. LUCA.
HOGENOMiHOG000208775.
KOiK11103.
OMAiYTAPGKM.
OrthoDBiPOG091H06ON.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
HAMAPiMF_01300. C4_dicarb_transport. 1 hit.
InterProiIPR023954. C4_dicarb_transport.
IPR001991. Na-dicarboxylate_symporter.
IPR018107. Na-dicarboxylate_symporter_CS.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 1 hit.
PROSITEiPS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5E9Q0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTKKFYQHL YFQVLTAISI GVAVGYYMPD TGTAMKPLGD GFIKMIKMII
60 70 80 90 100
TPIIFCTVVT GIAGMDDMKK VGRVGGKALL YFEAVSTLAL AIGLMVINVI
110 120 130 140 150
QPGVGMNADV TKLDTKGLAT YTATAAKSHS FADFALGIIP NSVVDAFAKG
160 170 180 190 200
EILQVLFFAI LFGLALSAMG EKGKPVYRMI DDVAHAFFGV VNIIMKFAPI
210 220 230 240 250
GAFGAMAFTI GKFGLGSLTK LGMLMGSFYL TCLLFIFVVL GTIGKLCGFN
260 270 280 290 300
IFKFISYIKE ELLIVLGTSS SESALPRLMA KLENLGCSKS VVGLVIPTGY
310 320 330 340 350
SFNLDGTSIY LTMAAVFVAQ ATNTPLDLTQ TLTILGVLML TSKGAAGVTG
360 370 380 390 400
SGFVTLAATF AAIPTIPVAG LALILGIDRF MSEARALTNL VGNGVATVVV
410 420 430
SRWENELNAT RMSQVLNKEL DEAAVEADLL MMDPEPEEA
Length:439
Mass (Da):46,549
Last modified:October 14, 2008 - v1
Checksum:iC3F4551415993188
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001124 Genomic DNA. Translation: ACH40224.1.
RefSeqiWP_012531656.1. NC_011146.1.

Genome annotation databases

EnsemblBacteriaiACH40224; ACH40224; Gbem_3225.
KEGGigbm:Gbem_3225.
PATRICi21990090. VBIGeoBem56306_3154.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001124 Genomic DNA. Translation: ACH40224.1.
RefSeqiWP_012531656.1. NC_011146.1.

3D structure databases

ProteinModelPortaliB5E9Q0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi404380.Gbem_3225.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACH40224; ACH40224; Gbem_3225.
KEGGigbm:Gbem_3225.
PATRICi21990090. VBIGeoBem56306_3154.

Phylogenomic databases

eggNOGiENOG4105CK2. Bacteria.
COG1301. LUCA.
HOGENOMiHOG000208775.
KOiK11103.
OMAiYTAPGKM.
OrthoDBiPOG091H06ON.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
HAMAPiMF_01300. C4_dicarb_transport. 1 hit.
InterProiIPR023954. C4_dicarb_transport.
IPR001991. Na-dicarboxylate_symporter.
IPR018107. Na-dicarboxylate_symporter_CS.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 1 hit.
PROSITEiPS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDCTA_GEOBB
AccessioniPrimary (citable) accession number: B5E9Q0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: October 14, 2008
Last modified: November 2, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.