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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Streptococcus pneumoniae serotype 19F (strain G54)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:SPG_0005
OrganismiStreptococcus pneumoniae serotype 19F (strain G54)
Taxonomic identifieri512566 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000929911 – 189Peptidyl-tRNA hydrolaseAdd BLAST189

Proteomic databases

PRIDEiB5E572

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB5E572
SMRiB5E572
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

B5E572-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKLLVGLGN PGDKYFETKH NVGFMLIDQL AKKQNVTFTH DKIFQADLAS
60 70 80 90 100
FFLNGEKIYL VKPTTFMNES GKAVHALLTY YGLDIDDLLI IYDDLDMEVG
110 120 130 140 150
KIRLRAKGSA GGHNGIKSII QHIGTQVFNR VKIGIGRPKN GMSVVHHVLS
160 170 180
KFDRDDYIGI LQSVDKVDDS VNYYLQEKNF EKTMQRYNG
Length:189
Mass (Da):21,391
Last modified:October 14, 2008 - v1
Checksum:i68BE01DCA04BEB12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001015 Genomic DNA Translation: ACF56061.1
RefSeqiWP_000163932.1, NC_011072.1

Genome annotation databases

EnsemblBacteriaiACF56061; ACF56061; SPG_0005
KEGGispx:SPG_0005

Similar proteinsi

Entry informationi

Entry nameiPTH_STRP4
AccessioniPrimary (citable) accession number: B5E572
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: October 14, 2008
Last modified: May 23, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

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