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B5E4N6

- GLGA_STRP4

UniProt

B5E4N6 - GLGA_STRP4

Protein

Glycogen synthase

Gene

glgA

Organism
Streptococcus pneumoniae serotype 19F (strain G54)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (14 Oct 2008)
      Previous versions | rss
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    Functioni

    Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

    Catalytic activityi

    ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei15 – 151ADP-glucoseUniRule annotation

    GO - Molecular functioni

    1. starch synthase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycogen biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Glycogen biosynthesis

    Enzyme and pathway databases

    BioCyciSPNE512566:GCA3-1042-MONOMER.
    UniPathwayiUPA00164.

    Protein family/group databases

    CAZyiGT5. Glycosyltransferase Family 5.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
    Alternative name(s):
    Starch [bacterial glycogen] synthaseUniRule annotation
    Gene namesi
    Name:glgAUniRule annotation
    Ordered Locus Names:SPG_1042
    OrganismiStreptococcus pneumoniae serotype 19F (strain G54)
    Taxonomic identifieri512566 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000008334: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 477477Glycogen synthasePRO_1000126104Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi512566.SPG_1042.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0297.
    HOGENOMiHOG000294940.
    KOiK00703.
    OrthoDBiEOG6JTC6Z.

    Family and domain databases

    HAMAPiMF_00484. Glycogen_synth.
    InterProiIPR001296. Glyco_trans_1.
    IPR011835. Glycogen/starch_synth.
    IPR013534. Starch_synth_cat_dom.
    [Graphical view]
    PfamiPF08323. Glyco_transf_5. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02095. glgA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B5E4N6-1 [UniParc]FASTAAdd to Basket

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    MKILFVAAEG APFSKTGGLG DVIGALPKSL VKAGHEVAVI LPYYDMVEAK    50
    FGNQIEDVLH FEVSVGWRRQ YCGIKKTVLN GVTFYFIDNQ YYFFRGHVYG 100
    DFDDGERFAF FQLAAIEAME RIDFIPDLLH VHDYHTAMIP FLLKEKYRWI 150
    QAYEDIETVL TIHNLEFQGQ FSEGMLGDLF GVGLERYADG TLRWNNCLNW 200
    MKAGILYANR VSTVSPSYAH EIMTSQFGCN LDQILKMESG KVSGIVNGID 250
    ADLYNPQTDA LLDYHFNQED LSGKAKNKAK LQERVGLPVR XXXPLVGIVS 300
    RLTRQKGFDV VVESLHHILQ EDVQIVLLGT GDPAFEGAFS WFAQIYPDKL 350
    STNITFDVKL AQEIYAACDL FLMPSRFEPC GLSQMMAMRY GTLPLVHEVG 400
    GLRDTVRAFN PIEGSGTGFS FDNLSPYWLN WTFQTALDLY RNHPDIWRNL 450
    QKQAMESDFS WDTACKSYLD LYHSLVN 477
    Length:477
    Mass (Da):54,173
    Last modified:October 14, 2008 - v1
    Checksum:i66B823535EE87EE5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001015 Genomic DNA. Translation: ACF56202.1.
    RefSeqiWP_000697299.1. NC_011072.1.
    YP_002037752.1. NC_011072.1.

    Genome annotation databases

    EnsemblBacteriaiACF56202; ACF56202; SPG_1042.
    GeneIDi6480317.
    KEGGispx:SPG_1042.
    PATRICi19687691. VBIStrPne77426_1097.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001015 Genomic DNA. Translation: ACF56202.1 .
    RefSeqi WP_000697299.1. NC_011072.1.
    YP_002037752.1. NC_011072.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 512566.SPG_1042.

    Protein family/group databases

    CAZyi GT5. Glycosyltransferase Family 5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACF56202 ; ACF56202 ; SPG_1042 .
    GeneIDi 6480317.
    KEGGi spx:SPG_1042.
    PATRICi 19687691. VBIStrPne77426_1097.

    Phylogenomic databases

    eggNOGi COG0297.
    HOGENOMi HOG000294940.
    KOi K00703.
    OrthoDBi EOG6JTC6Z.

    Enzyme and pathway databases

    UniPathwayi UPA00164 .
    BioCyci SPNE512566:GCA3-1042-MONOMER.

    Family and domain databases

    HAMAPi MF_00484. Glycogen_synth.
    InterProi IPR001296. Glyco_trans_1.
    IPR011835. Glycogen/starch_synth.
    IPR013534. Starch_synth_cat_dom.
    [Graphical view ]
    Pfami PF08323. Glyco_transf_5. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02095. glgA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: G54.
    2. "Pneumococcal beta glucoside metabolism investigated by whole genome comparison."
      Mulas L., Trappetti C., Hakenbeck R., Iannelli F., Pozzi G., Davidsen T.M., Tettelin H., Oggioni M.
      Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: G54.

    Entry informationi

    Entry nameiGLGA_STRP4
    AccessioniPrimary (citable) accession number: B5E4N6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: October 14, 2008
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3