B5E4I3 (B5E4I3_STRP4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
Short name=PEPC HAMAP-Rule MF_00595
Short name=PEPCase HAMAP-Rule MF_00595
EC=4.1.1.31 HAMAP-Rule MF_00595

Gene names

Name:	ppc HAMAP-Rule MF_00595 EMBL ACF55398.1
Ordered Locus Names:	SPG_0989 EMBL ACF55398.1

Organism

Streptococcus pneumoniae serotype 19F (strain G54) [Complete proteome] [HAMAP] EMBL ACF55398.1

Taxonomic identifier

512566 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus pneumoniae

Protein attributes

Sequence length	898 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595
Catalytic activity	Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595 SAAS SAAS018129
Cofactor	Magnesium By similarity. HAMAP-Rule MF_00595 SAAS SAAS018129
Subunit structure	Homotetramer By similarity. HAMAP-Rule MF_00595
Sequence similarities	Belongs to the PEPCase type 1 family. HAMAP-Rule MF_00595

Ontologies

Keywords
Biological process	Carbon dioxide fixation HAMAP-Rule MF_00595 SAAS SAAS018129
Ligand	Magnesium HAMAP-Rule MF_00595 SAAS SAAS018129 Pyruvate EMBL ACF55398.1
Molecular function	Lyase HAMAP-Rule MF_00595 SAAS SAAS018129 EMBL ACF55398.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbon fixation Inferred from electronic annotation. Source: HAMAP oxaloacetate metabolic process Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoenolpyruvate carboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	138	1	By similarity HAMAP-Rule MF_00595
	Active site	561	1	By similarity HAMAP-Rule MF_00595

Sequences

	Sequence		Length	Mass (Da)
	B5E4I3 [UniParc]. Last modified October 14, 2008. Version 1. Checksum: B5482C4DA6599CB7	FASTA	898	103,253
	10 20 30 40 50 60 MSLQKLENYS NKSVVKEEVL ILTELLEDIT KNMLAPETFE KIIQLKELST QEDYQGLNRL 70 80 90 100 110 120 VTSLSNDEMV YISRYFSILP LLINISEDVD LAYEINHQNN IDQDYLGKLS TTIKLVAEKE 130 140 150 160 170 180 NAVEILXHLN VVPVLTAHPT QVQRKSMLDL TNHIHSLLRK YRDVKLGLIN KDKWHNDLRR 190 200 210 220 230 240 YIEIIMQTDM IREKKLKVTN EITNAMEYYN SSFLKAVPHL TTEYKRLAQA HGLNLKQAKP 250 260 270 280 290 300 ITMGMWIGGD RDGNPFVTAK TLKQSALTQC EVIMNYYDKK IYQLYREFSL STSIVNVSKQ 310 320 330 340 350 360 VREMARQSKD NSIYREKELY RRALFDIQSK IQATKTYLIE DEEVGTRYET ANDFYKDLIA 370 380 390 400 410 420 IRDSLLENKG ESLISGDFVE LLQAVEIFGF YLASIDMRQD SSVYEACVAE LLKSAGIHSR 430 440 450 460 470 480 YSELSEEEKC DLLLKELEED PRILSATHAE KSELLAKELA IFKTARVLKD KLGDDVIRQT 490 500 510 520 530 540 IISHATSLSD MLELAILLKE VGLVDTERAR VQIVPLFETI EDLDHSEETM RKYLSLSLAK 550 560 570 580 590 600 KWIDSRNNYQ EIMLGYSDSN KDGGYLSSCW TLYKAQQQLT AIGDEFGVKV TFFHGRGGTV 610 620 630 640 650 660 GRGGGPTYEA ITSQPLKSIK DRIRLTEQGE VIGNKYGNKD AAYYNLEMLV SAAINRMITQ 670 680 690 700 710 720 KKSDTNTPNR YEAIMDQVVD RSYDIYRDLX FGNEHFYDYF FESSPIKAIS SFNIGSRPAA 730 740 750 760 770 780 RKTITEIGGL RAIPWVFSWS QSRVMFPGWY GVGSSFKEFI NKNPENIAIL RDMYQNWPFF 790 800 810 820 830 840 QSLLSNVDMV LSKSNMNIAF EYAKLCEDEQ VKAIYETILN EWQVTKNVIL AIEGHDELLA 850 860 870 880 890 DNPYLKASLD YRMPYFNILN YIQLELIKRQ RRGELSSDQE RLIHITINGI ATGLRNSG

References

[1]

"Annotated draft genomic sequence from a Streptococcus pneumoniae type 19F clinical isolate." Dopazo J., Mendoza A., Herrero J., Caldara F., Humbert Y., Friedli L., Guerrier M., Grand-Schenk E., Gandin C., de Francesco M., Polissi A., Buell G., Feger G., Garcia E., Peitsch M., Garcia-Bustos J.F. Microb. Drug Resist. 7:99-125(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: G54 EMBL ACF55398.1.

[2]

"Pneumococcal beta glucoside metabolism investigated by whole genome comparison." Mulas L., Trappetti C., Hakenbeck R., Iannelli F., Pozzi G., Davidsen T.M., Tettelin H., Oggioni M. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: G54 EMBL ACF55398.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001015 Genomic DNA. Translation: ACF55398.1.
RefSeq	YP_002037699.1. NC_011072.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	512566.SPG_0989.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACF55398; ACF55398; SPG_0989.
GeneID	6480017.
KEGG	spx:SPG_0989.
PATRIC	19687579. VBIStrPne77426_1042.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2352.
HOGENOM	HOG000238647.
KO	K01595.
OMA	AIPWVFG.
ProtClustDB	PRK00009.
Family and domain databases
HAMAP	MF_00595. PEPcase_type1.
InterPro	IPR021135. PEP_COase. IPR018129. PEP_COase_AS. IPR022805. PEP_COase_bac/pln-type. IPR015813. Pyrv/PenolPyrv_Kinase. [Graphical view]
Pfam	PF00311. PEPcase. 1 hit. [Graphical view]
PRINTS	PR00150. PEPCARBXLASE.
SUPFAM	SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
PROSITE	PS00781. PEPCASE_1. 1 hit. PS00393. PEPCASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B5E4I3_STRP4

Accession

Primary (citable) accession number: B5E4I3

Entry history

Integrated into UniProtKB/TrEMBL:	October 14, 2008
Last sequence update:	October 14, 2008
Last modified:	May 1, 2013
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)