Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Mitochondrial ribonuclease P protein 3

Gene

Mrpp3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial ribonuclease P protein 3
Short name:
Mitochondrial RNase P protein 3
Gene namesi
Name:Mrpp3
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 6

Organism-specific databases

RGDi1305089. RGD1305089.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 4646MitochondrionSequence analysisAdd
BLAST
Chaini47 – 587541Mitochondrial ribonuclease P protein 3PRO_0000360398Add
BLAST

Proteomic databases

PaxDbiB5DF07.
PeptideAtlasiB5DF07.
PRIDEiB5DF07.

Expressioni

Gene expression databases

BgeeiENSRNOG00000007043.
GenevisibleiB5DF07. RN.

Interactioni

Subunit structurei

Interacts with MRPP1/TRMT10C and MRPP2/HSD17B10.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000009306.

Family & Domainsi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410IE4T. Eukaryota.
ENOG4111GT9. LUCA.
GeneTreeiENSGT00390000002201.
HOGENOMiHOG000294131.
HOVERGENiHBG099441.
InParanoidiB5DF07.
KOiK17655.
OMAiCVIDGLN.
OrthoDBiEOG091G0JTR.
PhylomeDBiB5DF07.
TreeFamiTF324726.

Family and domain databases

InterProiIPR033495. MRPP3.
IPR031595. PRORP_C.
[Graphical view]
PANTHERiPTHR13547:SF1. PTHR13547:SF1. 1 hit.
PfamiPF16953. PRORP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

B5DF07-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFYLSGFRS FLKLWKSNPY FELGPATSSA SFFLGVHCVI GNQQRWFSVK
60 70 80 90 100
PTTPPNSKIL NLLVTKARTL KKGNDSNKQA SSGPHYFAAG EAKKRSHLSG
110 120 130 140 150
NPQNQGHTLP VKSTVQLPTK PLNSEEWDKL KEDFKGKASF EDFVISQMTR
160 170 180 190 200
SCSSVDVAKS LLAWVAAKNN GIVGYNLLVK YLYLCVFHKQ TSEVIDVYEI
210 220 230 240 250
MKAKYKSLES GGYTLLIRGL IHSDRWREAL LLLEDIKKVM VPSKKNYGDC
260 270 280 290 300
IQGALLHQDV NVAWSLYQEL VGHNLIPLLE TLKAFFDHGK DMNDDQYSNQ
310 320 330 340 350
LLDILLYLRN NQLYPGESFA HSIKTWFESI PGRQWKGQFT TIQKSGQCSS
360 370 380 390 400
CGRAIESIHL SPEEYEFLKE TIMRDVIDGG DQYKKTTPQE LKRFERFVKS
410 420 430 440 450
CPPFDIVIDG LNVAKMFPKG RESQNLLGIV SQLAQQNLQL LVLGRKHMLR
460 470 480 490 500
PSSQWRKDEM EQVRKQAHCF FADNISEDDP FLLYATLNSG SHCKFITKDL
510 520 530 540 550
LRDHKACLPD ARAQRLFFKW QQGHQLAITK GFLKSKLTFQ HILSYDTVVQ
560 570 580
TTGDTWHIPY DEDLVPRSSC EVPTKWLCLQ RKTPAPC
Length:587
Mass (Da):67,008
Last modified:October 14, 2008 - v1
Checksum:iF065F7875751BC08
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH473947 Genomic DNA. Translation: EDM03424.1.
BC168878 mRNA. Translation: AAI68878.1.
RefSeqiNP_001100200.1. NM_001106730.2.
UniGeneiRn.35652.

Genome annotation databases

EnsembliENSRNOT00000009304; ENSRNOP00000009306; ENSRNOG00000007043.
GeneIDi299050.
KEGGirno:299050.
UCSCiRGD:1305089. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH473947 Genomic DNA. Translation: EDM03424.1.
BC168878 mRNA. Translation: AAI68878.1.
RefSeqiNP_001100200.1. NM_001106730.2.
UniGeneiRn.35652.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000009306.

Proteomic databases

PaxDbiB5DF07.
PeptideAtlasiB5DF07.
PRIDEiB5DF07.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000009304; ENSRNOP00000009306; ENSRNOG00000007043.
GeneIDi299050.
KEGGirno:299050.
UCSCiRGD:1305089. rat.

Organism-specific databases

CTDi299050.
RGDi1305089. RGD1305089.

Phylogenomic databases

eggNOGiENOG410IE4T. Eukaryota.
ENOG4111GT9. LUCA.
GeneTreeiENSGT00390000002201.
HOGENOMiHOG000294131.
HOVERGENiHBG099441.
InParanoidiB5DF07.
KOiK17655.
OMAiCVIDGLN.
OrthoDBiEOG091G0JTR.
PhylomeDBiB5DF07.
TreeFamiTF324726.

Miscellaneous databases

PROiB5DF07.

Gene expression databases

BgeeiENSRNOG00000007043.
GenevisibleiB5DF07. RN.

Family and domain databases

InterProiIPR033495. MRPP3.
IPR031595. PRORP_C.
[Graphical view]
PANTHERiPTHR13547:SF1. PTHR13547:SF1. 1 hit.
PfamiPF16953. PRORP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMRRP3_RAT
AccessioniPrimary (citable) accession number: B5DF07
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: October 14, 2008
Last modified: September 7, 2016
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.