Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B5DEG1

- B5DEG1_RAT

UniProt

B5DEG1 - B5DEG1_RAT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Protein Itga8

Gene

Itga8

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. brain development Source: RGD
  2. cell adhesion Source: UniProtKB-KW
  3. cell projection organization Source: Ensembl
  4. establishment of protein localization Source: Ensembl
  5. extracellular matrix organization Source: Ensembl
  6. inner ear morphogenesis Source: Ensembl
  7. integrin-mediated signaling pathway Source: UniProtKB-KW
  8. memory Source: Ensembl
  9. metanephros development Source: Ensembl
  10. positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation Source: Ensembl
  11. positive regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
  12. smooth muscle tissue development Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

IntegrinUniRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotation

Keywords - Biological processi

Cell adhesionUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiREACT_198592. Molecules associated with elastic fibres.
REACT_198757. ECM proteoglycans.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Itga8Imported
Submitted name:
RGD1564327 proteinImported
Gene namesi
Name:Itga8Imported
Synonyms:RGD1564327Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 17

Organism-specific databases

RGDi621634. Itga8.

Subcellular locationi

Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

GO - Cellular componenti

  1. apical part of cell Source: Ensembl
  2. dendritic spine membrane Source: RGD
  3. integrin complex Source: InterPro
  4. perikaryon Source: RGD
  5. postsynaptic density Source: RGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

GenevestigatoriB5DEG1.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000022713.

Family & Domainsi

Sequence similaritiesi

Belongs to the integrin alpha chain family.UniRule annotation
Contains FG-GAP repeats.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiNOG26407.
GeneTreeiENSGT00760000118782.
HOGENOMiHOG000231603.
HOVERGENiHBG006186.
KOiK06584.
OMAiCRQIPFD.
OrthoDBiEOG7HQN77.
TreeFamiTF105391.

Family and domain databases

InterProiIPR013517. FG-GAP.
IPR013519. Int_alpha_beta-p.
IPR000413. Integrin_alpha.
IPR013649. Integrin_alpha-2.
IPR018184. Integrin_alpha_C_CS.
[Graphical view]
PfamiPF01839. FG-GAP. 2 hits.
PF00357. Integrin_alpha. 1 hit.
PF08441. Integrin_alpha2. 1 hit.
[Graphical view]
PRINTSiPR01185. INTEGRINA.
SMARTiSM00191. Int_alpha. 6 hits.
[Graphical view]
PROSITEiPS51470. FG_GAP. 7 hits.
PS00242. INTEGRIN_ALPHA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5DEG1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSARTHRGPP ENWAPPFACL CCVSAVLGML WSPVSLAFNL DVDKLTVYSG
60 70 80 90 100
PEGSYFGYSL DFYIPDARTA SVLVGAPKAN TSQPDIVEGG AVYYCPWPAE
110 120 130 140 150
RSAQCKQIPF DTTNNRKIRV NGTKEPIEFK SNQWFGATVR AHKGKVVACA
160 170 180 190 200
PLYHWRTLKP NPAKDPVGTC YVAIQNFSAY AEHSPCRNSN VDPEGQGYCQ
210 220 230 240 250
AGFSLDFYKN GDLIVGGPGS FYWQGQVITV SVADIIANYS FKDILRKLAA
260 270 280 290 300
EKQTDVAPAS YDDSYLGYSV AAGEFTGDSL QELVAGIPRG AQNFGYVSII
310 320 330 340 350
NSTDMTFIQN FTGEQMASYF GYTVVVSDVN NDGMDDILVG APLFMEREFE
360 370 380 390 400
SNPREVGQVY LYLQVSALLF QDPQVLTGTE TFGRFGSSVA HLGDLNQDGY
410 420 430 440 450
NDIAIGVPFA GKDQRGKVLI YNGNARGLHS KPSQVLQGIW GSQTIPSGFG
460 470 480 490 500
FSLRGDADID KNDYPDLLVG AFGEGKVAVY RARPVVTVDA QLLLHPMIIN
510 520 530 540 550
LENKTCQIPE FPTPVACFSL RVCASIAGQS ISNTVALMAE VQLDFLKQKG
560 570 580 590 600
AIKRTLFLHN HQSHLIFPFV MRQQKSLHCQ DFMVYLRDET EFRDKLSPIN
610 620 630 640 650
VSLNYSLDDS TFEDGLEVKP ILNHYRENVV TEQAHILVDC GEDNLCVPDL
660 670 680 690 700
RLSARPDKQE IIIGDENHLM LIINARNEGE GAYEAELFVM IPEEADYVGI
710 720 730 740 750
ERNNKGLRLL SCEYKMENVT RMVVCDLGNP MVTGTNFSLG LRFAVPRLEK
760 770 780 790 800
TNMSINFDLQ IRSSNKDNPD SNFVSVQINV TAVAQVEIRG VSHPPQIVLP
810 820 830 840 850
IHNWEPAEEP HKEEEVGPLV EHIYELHNIG PSTISDSILE VGWPFSAREE
860 870 880 890 900
FLLYVFHLQT LGPLQCQTNP EINPQDIKPA ASPEDTPELS AFLRNATIPH
910 920 930 940 950
LVRKRDVPVV QPHRQSPAKI LNCTNIDCLQ ISCAVGRLGG GESAVLKVRS
960 970 980 990 1000
RLWAHTFLQR KNDPYALASL VSFEVKKIPY KEQPAKLPAG STAIKTSVIW
1010 1020 1030 1040 1050
ATPNVSFSIP LWVIILAILL GLLVLAILTL ALWKCGFFDR ARPPQDEMTD
1060
REQLTSDKTP EA
Length:1,062
Mass (Da):117,575
Last modified:October 14, 2008 - v1
Checksum:i24F33BC97E4B670C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06093120 Genomic DNA. No translation available.
AABR06093121 Genomic DNA. No translation available.
AABR06093122 Genomic DNA. No translation available.
AABR06093123 Genomic DNA. No translation available.
AABR06093124 Genomic DNA. No translation available.
AABR06093125 Genomic DNA. No translation available.
AABR06093126 Genomic DNA. No translation available.
AABR06093127 Genomic DNA. No translation available.
AABR06093128 Genomic DNA. No translation available.
AABR06093129 Genomic DNA. No translation available.
AABR06093130 Genomic DNA. No translation available.
AABR06093131 Genomic DNA. No translation available.
AABR06093132 Genomic DNA. No translation available.
AABR06093133 Genomic DNA. No translation available.
AABR06093134 Genomic DNA. No translation available.
AABR06093135 Genomic DNA. No translation available.
AABR06093136 Genomic DNA. No translation available.
AABR06093137 Genomic DNA. No translation available.
BC168655 mRNA. Translation: AAI68655.1.
RefSeqiNP_001167443.1. NM_001173972.1.
UniGeneiRn.69726.

Genome annotation databases

EnsembliENSRNOT00000022711; ENSRNOP00000022713; ENSRNOG00000016538.
GeneIDi364786.
KEGGirno:364786.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06093120 Genomic DNA. No translation available.
AABR06093121 Genomic DNA. No translation available.
AABR06093122 Genomic DNA. No translation available.
AABR06093123 Genomic DNA. No translation available.
AABR06093124 Genomic DNA. No translation available.
AABR06093125 Genomic DNA. No translation available.
AABR06093126 Genomic DNA. No translation available.
AABR06093127 Genomic DNA. No translation available.
AABR06093128 Genomic DNA. No translation available.
AABR06093129 Genomic DNA. No translation available.
AABR06093130 Genomic DNA. No translation available.
AABR06093131 Genomic DNA. No translation available.
AABR06093132 Genomic DNA. No translation available.
AABR06093133 Genomic DNA. No translation available.
AABR06093134 Genomic DNA. No translation available.
AABR06093135 Genomic DNA. No translation available.
AABR06093136 Genomic DNA. No translation available.
AABR06093137 Genomic DNA. No translation available.
BC168655 mRNA. Translation: AAI68655.1 .
RefSeqi NP_001167443.1. NM_001173972.1.
UniGenei Rn.69726.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000022713.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000022711 ; ENSRNOP00000022713 ; ENSRNOG00000016538 .
GeneIDi 364786.
KEGGi rno:364786.

Organism-specific databases

CTDi 8516.
RGDi 621634. Itga8.

Phylogenomic databases

eggNOGi NOG26407.
GeneTreei ENSGT00760000118782.
HOGENOMi HOG000231603.
HOVERGENi HBG006186.
KOi K06584.
OMAi CRQIPFD.
OrthoDBi EOG7HQN77.
TreeFami TF105391.

Enzyme and pathway databases

Reactomei REACT_198592. Molecules associated with elastic fibres.
REACT_198757. ECM proteoglycans.

Miscellaneous databases

NextBioi 686038.
PROi B5DEG1.

Gene expression databases

Genevestigatori B5DEG1.

Family and domain databases

InterProi IPR013517. FG-GAP.
IPR013519. Int_alpha_beta-p.
IPR000413. Integrin_alpha.
IPR013649. Integrin_alpha-2.
IPR018184. Integrin_alpha_C_CS.
[Graphical view ]
Pfami PF01839. FG-GAP. 2 hits.
PF00357. Integrin_alpha. 1 hit.
PF08441. Integrin_alpha2. 1 hit.
[Graphical view ]
PRINTSi PR01185. INTEGRINA.
SMARTi SM00191. Int_alpha. 6 hits.
[Graphical view ]
PROSITEi PS51470. FG_GAP. 7 hits.
PS00242. INTEGRIN_ALPHA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: LungImported.
  2. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiB5DEG1_RAT
AccessioniPrimary (citable) accession number: B5DEG1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 14, 2008
Last sequence update: October 14, 2008
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3