B5BP46 (YP52_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative glutathione S-transferase C1183.02
EC=2.5.1.18

Gene names

ORF Names:

SPBC460.02c

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]

Taxonomic identifier

284812 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › Schizosaccharomyces pombe

Protein attributes

Sequence length	220 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the oxidative stress response and detoxification By similarity.
Catalytic activity	RX + glutathione = HX + R-S-glutathione.
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the GST superfamily. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	glutathione transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 220	220	Putative glutathione S-transferase C1183.02		PRO_0000415923
Regions
	Domain	1 – 81	81	GST N-terminal
	Domain	89 – 216	128	GST C-terminal

Sequences

	Sequence		Length	Mass (Da)
	B5BP46 [UniParc]. Last modified October 14, 2008. Version 1. Checksum: 9BC90C709E47BC91	FASTA	220	25,717
	10 20 30 40 50 60 MFLGTIYSFK TNTRTPCLLE LAKRLDLQVD LVETYHHKFP TDLAAKFPLQ KLPVFIGADG 70 80 90 100 110 120 FELSEVIAIF KYFYEKGKHN DKEGLGPINE IEEAEMLKWM CFINFDIVTP QIVRPWVDMF 130 140 150 160 170 180 RGSVPYEDKA FKESAARAID SLKIINELVK DRTYLVGDRF TLADLFFGSM LRRFFHSIID 190 200 210 220 EKTRKELPHL TRYYVTMFHQ AKLEAYYPLE LPLTVTVPNN

References

[1]

"The gap-filling sequence on the left arm of chromosome 2 in fission yeast Schizosaccharomyces pombe." Sasaki M., Idiris A., Tada A., Kumagai H., Giga-Hama Y., Tohda H. Yeast 25:673-679(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB325691 Genomic DNA. Translation: BAG68902.1.
3D structure databases
ProteinModelPortal	B5BP46.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SPBC460.02c.1; SPBC460.02c.1:pep; SPBC460.02c.
Organism-specific databases
PomBase	SPBC460.02c.
Family and domain databases
Gene3D	1.20.1050.10. 1 hit. 3.40.30.10. 1 hit.
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR012336. Thioredoxin-like_fold. [Graphical view]
Pfam	PF00043. GST_C. 1 hit. [Graphical view]
SUPFAM	SSF47616. GST_C_like. 1 hit. SSF52833. Thiordxn-like_fd. 1 hit.
PROSITE	PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YP52_SCHPO

Accession

Primary (citable) accession number: B5BP46

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 21, 2012
Last sequence update:	October 14, 2008
Last modified:	March 6, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program