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Protein

Putative glutathione S-transferase C1183.02

Gene

SPBC460.02c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the oxidative stress response and detoxification.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative glutathione S-transferase C1183.02 (EC:2.5.1.18)
Gene namesi
ORF Names:SPBC460.02c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485 Componenti: Chromosome II, gap-filling sequence

Organism-specific databases

PomBaseiSPBC460.02c.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 220220Putative glutathione S-transferase C1183.02PRO_0000415923Add
BLAST

Proteomic databases

MaxQBiB5BP46.

Interactioni

Protein-protein interaction databases

STRINGi4896.SPBC460.02c.1.

Structurei

3D structure databases

ProteinModelPortaliB5BP46.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 8181GST N-terminalAdd
BLAST
Domaini89 – 216128GST C-terminalAdd
BLAST

Sequence similaritiesi

Belongs to the GST superfamily.Curated
Contains 1 GST C-terminal domain.Curated
Contains 1 GST N-terminal domain.Curated

Phylogenomic databases

InParanoidiB5BP46.
OMAiWRESHPE.
OrthoDBiEOG7RBZK2.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B5BP46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLGTIYSFK TNTRTPCLLE LAKRLDLQVD LVETYHHKFP TDLAAKFPLQ
60 70 80 90 100
KLPVFIGADG FELSEVIAIF KYFYEKGKHN DKEGLGPINE IEEAEMLKWM
110 120 130 140 150
CFINFDIVTP QIVRPWVDMF RGSVPYEDKA FKESAARAID SLKIINELVK
160 170 180 190 200
DRTYLVGDRF TLADLFFGSM LRRFFHSIID EKTRKELPHL TRYYVTMFHQ
210 220
AKLEAYYPLE LPLTVTVPNN
Length:220
Mass (Da):25,717
Last modified:October 14, 2008 - v1
Checksum:i9BC90C709E47BC91
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB325691 Genomic DNA. Translation: BAG68902.1.

Genome annotation databases

EnsemblFungiiSPBC460.02c.1; SPBC460.02c.1:pep; SPBC460.02c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB325691 Genomic DNA. Translation: BAG68902.1.

3D structure databases

ProteinModelPortaliB5BP46.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4896.SPBC460.02c.1.

Proteomic databases

MaxQBiB5BP46.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC460.02c.1; SPBC460.02c.1:pep; SPBC460.02c.

Organism-specific databases

PomBaseiSPBC460.02c.

Phylogenomic databases

InParanoidiB5BP46.
OMAiWRESHPE.
OrthoDBiEOG7RBZK2.

Miscellaneous databases

PROiB5BP46.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The gap-filling sequence on the left arm of chromosome 2 in fission yeast Schizosaccharomyces pombe."
    Sasaki M., Idiris A., Tada A., Kumagai H., Giga-Hama Y., Tohda H.
    Yeast 25:673-679(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiYP52_SCHPO
AccessioniPrimary (citable) accession number: B5BP46
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2012
Last sequence update: October 14, 2008
Last modified: June 24, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.